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RER1-209 ,RER1 ,O15258
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 70
  • Number of Interaction partner in hippie: 104
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACKR2-201 ACKR2 O00590 Atypical chemokine receptor 2 chr3 Not Cancer Driver No 1 hippie, biogrid 51 25 4 4 0
APOB-201 APOB P04114 Apolipoprotein B-100 chr2 Not Cancer Driver No 1 hippie, biogrid 795 317 51 51 3
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 94 419 52 52 12
AQP3-201 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 25 12 0 0 0
ATG16L1-203 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 54 240 19 19 1
ATP13A3-202 ATP13A3 Q9H7F0 Polyamine-transporting ATPase 13A3 chr3 Not Cancer Driver No 1 hippie, biogrid 110 49 6 6 1
ATP1A3-214 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 151 116 21 21 41
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
ATP5F1A-202 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 48 23 3 3 2
ATP5ME-201 ATP5ME P56385 ATP synthase subunit e, mitochondrial chr4 Not Cancer Driver No 1 hippie 4 18 1 1 0
ATP5MG-201 ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 Not Cancer Driver No 1 hippie 15 0 0 0 0
ATP5PD-201 ATP5PD O75947 ATP synthase subunit d, mitochondrial chr17 Not Cancer Driver No 1 hippie 8 15 1 1 0
ATP5PO-201 ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 hippie 17 9 2 2 0
B3GAT1-201 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 59 93 24 24 0
BCAP31-201 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 27 104 13 13 0
C5AR1-201 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 52 0 0 0 0
CAV2-201 CAV2 P51636 Caveolin-2 chr7 Not Cancer Driver No 1 hippie, biogrid 13 5 2 2 0
CCR1-201 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 47 14 0 0 0
CCR6-201 CCR6 P51684 C-C chemokine receptor type 6 chr6 Not Cancer Driver No 1 hippie, biogrid 46 13 2 2 0
CD274-202 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 26 54 9 9 0
CHRNA9-201 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 Not Cancer Driver No 1 hippie, biogrid 55 23 3 3 0
CNR2-201 CNR2 P34972 Cannabinoid receptor 2 chr1 Not Cancer Driver No 1 intact, hippie 44 21 4 4 0
DPEP1-210 DPEP1 P16444 Dipeptidase 1 chr16 Not Cancer Driver No 2 hippie, biogrid 42 41 7 7 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 77 61 4 4 2
ENDOD1-201 ENDOD1 O94919 Endonuclease domain-containing 1 protein chr11 Not Cancer Driver No 1 hippie, biogrid 36 72 5 5 0
ENST00000644613 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 151 115 21 21 39
ERGIC1-202 ERGIC1 Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 27 26 0 0 0
ERGIC3-202 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 Not Cancer Driver No 1 hippie, biogrid 32 23 1 1 0
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FFAR1-201 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
FPR2-201 FPR2 P25090 N-formyl peptide receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 92 26 7 7 0
GJD3-201 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 2 80 0 0 0
GPR182-201 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 38 33 5 5 0
GPR84-201 GPR84 Q9NQS5 G-protein coupled receptor 84 chr12 Not Cancer Driver No 1 hippie, biogrid 51 89 11 11 0
HAP1-201 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 56 463 37 37 0
HBA1-201 HBA2 P69905 Hemoglobin subunit alpha chr16 Not Cancer Driver No 1 biogrid 4 4 0 0 0
HBA2-201 HBA2 P69905 Hemoglobin subunit alpha chr16 Not Cancer Driver No 1 biogrid 8 4 0 0 0
HBB-201 HBB P68871 Hemoglobin subunit beta chr11 Not Cancer Driver No 1 hippie, biogrid 32 7 1 1 5
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 517 971 113 113 1
HLA-DPA1-248 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 Not Cancer Driver No 1 hippie, biogrid 22 30 3 3 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie 129 16 2 2 10
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 23 25 3 3 0
HTR1B-201 HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 Not Cancer Driver No 1 hippie, biogrid 72 33 13 13 0
IFITM3-201 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 7 19 2 2 0
IMMT-204 IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 75 402 39 39 0
KCNK1-202 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 59 21 4 4 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 intact, hippie, biogrid 771 7 2 2 22
LAMP1-201 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 36 94 8 8 0
LAMP3-201 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 57 223 34 34 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
MFSD4A-201 MFSD4A Q8N468 Major facilitator superfamily domain-containing protein 4A chr1 Not Cancer Driver No 1 hippie 33 29 2 2 0
NEDD4-208 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 99 717 55 55 0
NIPAL1-201 NIPAL1 Q6NVV3 Magnesium transporter NIPA3 chr4 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
NPC1-201 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 113 25 0 0 135
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NUP155-201 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 128 221 17 17 1
P2RY2-203 P2RY2 P41231 P2Y purinoceptor 2 chr11 Not Cancer Driver No 1 hippie, biogrid 51 60 8 8 0
P2RY8-201 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX Census, Compendium Yes 1 hippie, biogrid 84 23 4 4 0
PAK1-202 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 36 300 19 19 2
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PMP22-201 PMP22 Q01453 Peripheral myelin protein 22 chr17 Not Cancer Driver No 1 hippie 17 0 0 0 32
POMK-201 POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 hippie, biogrid 40 30 7 7 3
PTBP3-204 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 39 114 8 8 0
RAB1A-203 RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 9 38 2 2 0
RAB5C-201 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 17 51 2 2 0
REEP5-202 REEP5 Q00765 Receptor expression-enhancing protein 5 chr5 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RNF130-205 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 Not Cancer Driver No 1 biogrid 32 43 2 2 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
RNF2-202 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 26 203 15 15 1
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
S1PR1-201 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 69 29 5 5 0
SCAND1-201 SCAND1 P57086 SCAN domain-containing protein 1 chr20 Not Cancer Driver No 1 intact, hippie 7 152 5 5 0
SEC62-201 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 12 211 9 9 0
SERINC2-201 SERINC2 Q96SA4 Serine incorporator 2 chr1 Not Cancer Driver No 1 hippie, biogrid 36 6 0 0 0
SH3GL3-202 SH3GL3 Q99963 Endophilin-A3 chr15 Not Cancer Driver No 1 hippie, biogrid 66 84 19 19 0
SIGMAR1-201 SIGMAR1 Q99720 Sigma non-opioid intracellular receptor 1 chr9 Not Cancer Driver No 1 hippie, biogrid 20 2 0 0 1
SLC11A2-229 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 47 39 4 4 3
SLC2A12-201 SLC2A12 Q8TD20 Solute carrier family 2, facilitated glucose transporter member 12 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 66 52 2 2 0
SLC30A2-201 SLC30A2 Q9BRI3 Proton-coupled zinc antiporter SLC30A2 chr1 Not Cancer Driver No 1 hippie, biogrid 48 47 5 5 2
SLC35F2-204 SLC35F2 Q8IXU6 Solute carrier family 35 member F2 chr11 Not Cancer Driver No 1 hippie, biogrid 37 12 0 0 0
SLC39A4-202 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 1 hippie, biogrid 58 116 9 9 9
SPPL2B-209 SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 0 101 0 0 0
STRA6-202 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 Not Cancer Driver No 1 hippie, biogrid 62 84 13 13 6
STX12-201 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 1 hippie, biogrid 13 156 6 6 0
SYCE3-202 SYCE3 A1L190 Synaptonemal complex central element protein 3 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 3 41 1 1 0
SYNGR1-203 SYNGR1 O43759 Synaptogyrin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 17 48 3 3 0
SYT16-206 SYT16 Q17RD7 Synaptotagmin-16 chr14 Not Cancer Driver No 1 intact, hippie 145 396 91 91 0
SYVN1-203 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 25 284 0 0 0
TCTN2-201 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 62 23 2 2 0
TCTN3-203 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 32 71 5 5 1
TMEM17-201 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 15 14 1 1 0
TMEM184A-201 TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 Not Cancer Driver No 1 hippie, biogrid 45 76 12 12 0
TMEM185A-207 TMEM185A Q8NFB2 Transmembrane protein 185A chrX Not Cancer Driver No 1 hippie, biogrid 19 19 0 0 0
TMEM216-203 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 7 0 0 0 5
TMEM72-201 TMEM72 A0PK05 Transmembrane protein 72 chr10 Not Cancer Driver No 1 hippie, biogrid 37 98 17 17 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TSPAN5-201 TSPAN5 P62079 Tetraspanin-5 chr4 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
TSPAN8-201 TSPAN8 P19075 Tetraspanin-8 chr12 Not Cancer Driver No 1 hippie, biogrid 37 0 0 0 0
UBL4A-202 UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 1 hippie 17 16 4 4 0
UNK-205 UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 60 513 33 33 0
UPK1A-201 UPK1A O00322 Uroplakin-1a chr19 Not Cancer Driver No 1 intact, hippie, biogrid 21 0 0 0 0
VDAC2-203 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 22 9 1 1 0
VIPR1-201 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 27 10 0 0 0
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 18 37 1 1 0
WIPF1-217 WIPF1 O43516 WAS/WASL-interacting protein family member 1 chr2 Not Cancer Driver No 1 intact, hippie 88 505 88 88 0