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RGS2-201 ,RGS2 ,P41220
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 23
  • Number of Interaction partner in hippie: 78
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADCY5-202 ADCY5 O95622 Adenylate cyclase type 5 chr3 Not Cancer Driver No 1 hippie 181 271 17 17 3
ADRA1A-204 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 Not Cancer Driver No 1 hippie 90 40 1 1 0
ADRB2-201 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 36 35 4 4 0
ARFGAP1-203 ARFGAP1 Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 46 265 31 31 0
BBS10-201 BBS10 Q8TAM1 Bardet-Biedl syndrome 10 protein chr12 Not Cancer Driver No 1 hippie 46 67 6 6 23
CALM1-201 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 12 115 10 10 6
CALM2-201 CALM1 P0DP23 Calmodulin-1 chr2 Not Cancer Driver No 1 hippie 13 115 8 8 6
CALM3-201 CALM1 P0DP23 Calmodulin-1 chr19 Not Cancer Driver No 1 hippie 13 115 8 8 6
CEP126-201 CEP126 Q9P2H0 Centrosomal protein of 126 kDa chr11 Not Cancer Driver No 1 hippie 146 820 112 112 0
CHD3-201 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 187 1017 92 92 17
CIAO1-203 CIAO1 O76071 Probable cytosolic iron-sulfur protein assembly protein CIAO1 chr2 Not Cancer Driver No 1 hippie 25 20 2 2 0
CLTA-201 CLTA P09496 Clathrin light chain A chr9 Not Cancer Driver No 1 hippie 17 194 10 10 0
COMT-202 COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 hippie 16 5 0 0 0
COPB1-202 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie 74 95 6 6 1
COPB2-201 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 1 hippie 70 114 18 18 0
CRMP1-202 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 1 hippie 102 96 12 12 0
CTSB-202 CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie 36 7 2 2 0
CUL4B-231 CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 83 207 23 23 2
DDR1-225 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie, biogrid 98 253 41 41 0
DUSP21-201 DUSP21 Q9H596 Dual specificity protein phosphatase 21 chrX Not Cancer Driver No 1 hippie 37 0 0 0 0
DYNLL1-201 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
EIF3E-201 EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 1 hippie 59 27 2 2 0
EIF3L-215 EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 1 hippie 45 41 1 1 0
ENST00000588705 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 Not Cancer Driver No 1 hippie 3 0 0 0 2
EPHX1-201 EPHX1 P07099 Epoxide hydrolase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 63 7 0 0 0
FBXO44-202 FBXO44 Q9H4M3 F-box only protein 44 chr1 Not Cancer Driver No 1 hippie 24 27 3 3 0
FZD5-201 FZD5 Q13467 Frizzled-5 chr2 Not Cancer Driver No 1 hippie 39 58 3 3 0
GDE1-201 GDE1 Q9NZC3 Glycerophosphodiester phosphodiesterase 1 chr16 Not Cancer Driver No 1 hippie 27 37 1 1 0
GIT1-201 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 1 hippie, biogrid 48 434 26 26 0
GNA15-201 GNA15 P30679 Guanine nucleotide-binding protein subunit alpha-15 chr19 Not Cancer Driver No 1 hippie 38 15 4 4 0
GNAI3-201 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie 36 12 0 0 1
GNAQ-201 GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 1 hippie 82 14 1 1 1
GNAS-214 GNAS Q5JWF2 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas chr20 Census, Compendium Yes 1 hippie 112 718 33 33 2
HAUS5-201 HAUS5 O94927 HAUS augmin-like complex subunit 5 chr19 Not Cancer Driver No 1 hippie 67 182 16 16 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie, biogrid 82 252 28 28 0
IBTK-201 IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 Not Cancer Driver No 1 hippie 107 364 33 33 0
IER3IP1-201 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 Not Cancer Driver No 1 hippie 3 0 0 0 2
KBTBD7-201 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 2 hippie, biogrid 63 107 6 6 0
KLK8-212 KLK8 O60259 Kallikrein-8 chr19 Not Cancer Driver No 1 hippie 46 77 13 13 0
LIG1-201 LIG1 P18858 DNA ligase 1 chr19 Not Cancer Driver No 1 hippie 99 400 50 50 3
LRFN1-201 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 77 278 31 31 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 402 91 13 13 20
MARCHF6-201 MARCHF6 O60337 E3 ubiquitin-protein ligase MARCHF6 chr5 Not Cancer Driver No 1 intact 87 114 10 10 0
MB-202 MB P02144 Myoglobin chr22 Not Cancer Driver No 1 hippie, biogrid 12 39 4 4 0
METAP2-202 METAP2 P50579 Methionine aminopeptidase 2 chr12 Not Cancer Driver No 2 hippie, biogrid 36 177 14 14 0
METTL18-202 METTL18 O95568 Histidine protein methyltransferase 1 homolog chr1 Not Cancer Driver No 1 hippie 26 126 7 7 0
MIPOL1-216 MIPOL1 Q8TD10 Mirror-image polydactyly gene 1 protein chr14 Not Cancer Driver No 2 hippie, biogrid 42 274 27 27 0
MTUS2-206 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 hippie 308 1216 290 290 0
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 3 hippie, biogrid 193 891 140 140 0
NIPSNAP1-201 NIPSNAP1 Q9BPW8 Protein NipSnap homolog 1 chr22 Not Cancer Driver No 1 hippie, biogrid 26 9 0 0 0
NISCH-201 NISCH Q9Y2I1 Nischarin chr3 Not Cancer Driver No 1 hippie, biogrid 127 421 33 33 0
PPP1R9A-207 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 1 hippie 159 891 128 128 0
PRKCA-202 PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 70 155 17 17 0
PRKCB-201 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 153 148 26 26 0
PRKCG-201 PRKCG P05129 Protein kinase C gamma type chr19 Not Cancer Driver No 1 hippie 141 152 36 36 4
PRKCSH-209 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 47 320 28 28 0
PRKG1-204 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 Not Cancer Driver No 1 hippie 129 93 18 18 1
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PTPN13-202 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 2 hippie, biogrid 213 1235 110 110 0
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie 15 58 3 3 0
RABAC1-201 RABAC1 Q9UI14 Prenylated Rab acceptor protein 1 chr19 Not Cancer Driver No 1 hippie 17 13 0 0 0
RAP1B-201 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie 20 14 2 2 0
REEP5-202 REEP5 Q00765 Receptor expression-enhancing protein 5 chr5 Not Cancer Driver No 1 hippie 23 0 0 0 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 64 420 31 31 0
SCN5A-202 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 Not Cancer Driver No 1 hippie 381 554 117 117 181
SERPINA10-201 SERPINA10 Q9UK55 Protein Z-dependent protease inhibitor chr14 Not Cancer Driver No 2 hippie, biogrid 94 75 17 17 0
STK26-202 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 2 hippie, biogrid 44 119 14 14 0
STRIP1-201 STRIP1 Q5VSL9 Striatin-interacting protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 76 267 22 22 0
STXBP4-201 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 Not Cancer Driver No 2 hippie, biogrid 58 212 20 20 0
TAF2-201 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 hippie, biogrid 83 242 21 21 1
TSPAN15-201 TSPAN15 O95858 Tetraspanin-15 chr10 Not Cancer Driver No 1 hippie 18 0 0 0 0
TUBB2B-201 TUBB2B Q9BVA1 Tubulin beta-2B chain chr6 Not Cancer Driver No 1 hippie 33 68 4 4 10
VPS29-206 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
WDR74-201 WDR74 Q6RFH5 WD repeat-containing protein 74 chr11 Not Cancer Driver No 1 hippie, biogrid 31 177 12 12 0
XRCC6-202 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 49 140 8 8 0
ZBTB48-202 ZBTB48 P10074 Telomere zinc finger-associated protein chr1 Not Cancer Driver No 1 hippie 40 237 15 15 0
ZNF579-201 ZNF579 Q8NAF0 Zinc finger protein 579 chr19 Not Cancer Driver No 1 hippie 23 451 13 13 0
ZYX-201 ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie 49 385 29 29 0