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RPAP2-203 ,RPAP2 ,Q8IXW5
  • Number of Interaction partner in intact: 29
  • Number of Interaction partner in biogrid: 115
  • Number of Interaction partner in hippie: 135
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 96 43 5 5 4
APOC3-201 APOC3 P02656 Apolipoprotein C-III chr11 Not Cancer Driver No 1 intact, hippie, biogrid 10 13 2 2 1
ARMC5-201 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 Not Cancer Driver No 1 hippie, biogrid 96 268 22 22 14
ARMCX3-203 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 29 77 7 7 0
ASB6-201 ASB6 Q9NWX5 Ankyrin repeat and SOCS box protein 6 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 31 31 3 3 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
BRD1-202 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 117 424 47 47 0
CCNF-202 CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 77 221 16 16 3
CCT5-201 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 hippie, biogrid 65 72 8 8 1
CCT8L2-201 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 196 104 41 41 0
CDK19-202 CDK19 Q9BWU1 Cyclin-dependent kinase 19 chr6 Not Cancer Driver No 1 hippie, biogrid 46 191 18 18 6
CEP120-201 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 70 449 35 35 1
CEP43-202 CEP43 O95684 Centrosomal protein 43 chr6 Not Cancer Driver No 1 intact 32 274 27 27 0
CNTRL-205 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 166 1560 115 115 0
CPNE2-201 CPNE2 Q96FN4 Copine-2 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 45 32 3 3 0
CRCP-203 CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 Not Cancer Driver No 1 hippie, biogrid 8 114 4 4 0
DNM2-201 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie, biogrid 95 271 32 32 16
DXO-201 DXO O77932 Decapping and exoribonuclease protein chr6 Not Cancer Driver No 3 hippie, biogrid 31 143 11 11 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EHBP1-201 EHBP1 Q8NDI1 EH domain-binding protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 101 916 88 88 0
EIF4A2-201 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 Census Yes 1 hippie, biogrid 64 27 11 11 0
ENST00000684631 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
ENST00000705256 CEP43 O95684 Centrosomal protein 43 chr6 Not Cancer Driver No 1 intact 0 0 0 0 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
FAM168A-201 FAM168A Q92567 Protein FAM168A chr11 Not Cancer Driver No 1 hippie, biogrid 15 141 10 10 0
FGF11-201 FGF11 Q92914 Fibroblast growth factor 11 chr17 Not Cancer Driver No 1 hippie, biogrid 13 68 2 2 0
G3BP1-201 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 55 352 38 38 0
GPN1-211 GPN1 Q9HCN4 GPN-loop GTPase 1 chr2 Not Cancer Driver No 3 hippie, biogrid 25 117 8 8 0
GPN3-201 GPN3 Q9UHW5 GPN-loop GTPase 3 chr12 Not Cancer Driver No 5 intact, hippie, biogrid 13 19 0 0 0
GTF3C3-201 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 Not Cancer Driver No 1 hippie, biogrid 62 196 10 10 0
HELLS-201 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 Not Cancer Driver No 1 hippie, biogrid 52 228 16 16 0
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
INTS1-201 INTS1 Q8N201 Integrator complex subunit 1 chr7 Not Cancer Driver No 1 hippie, biogrid 184 370 35 35 1
INTS3-201 INTS3 Q68E01 Integrator complex subunit 3 chr1 Not Cancer Driver No 1 hippie, biogrid 91 213 19 19 0
INTS4-208 INTS4 Q96HW7 Integrator complex subunit 4 chr11 Not Cancer Driver No 1 hippie, biogrid 97 82 5 5 0
INTS7-203 INTS7 Q9NVH2 Integrator complex subunit 7 chr1 Not Cancer Driver No 1 hippie, biogrid 74 89 9 9 0
ITCH-201 ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 Not Cancer Driver No 1 hippie 75 335 33 33 0
KHDRBS2-201 KHDRBS2 Q5VWX1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 137 270 114 114 0
KHDRBS3-201 KHDRBS3 O75525 KH domain-containing, RNA-binding, signal transduction-associated protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 51 230 32 32 0
KRT8-218 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 49 225 23 23 3
KSR2-201 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 Not Cancer Driver No 1 intact, hippie 192 428 102 102 0
LMO2-202 LMO2 P25791 Rhombotin-2 chr11 Census Yes 2 intact, hippie, biogrid 24 14 0 0 0
LRCH2-201 LRCH2 Q5VUJ6 Leucine-rich repeat and calponin homology domain-containing protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 81 458 52 52 0
MAPRE3-201 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 24 120 11 11 0
MED1-201 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 3 hippie, biogrid 81 1104 50 50 0
MED10-201 MED10 Q9BTT4 Mediator of RNA polymerase II transcription subunit 10 chr5 Not Cancer Driver No 1 hippie, biogrid 15 13 3 3 0
MED13-201 MED13 Q9UHV7 Mediator of RNA polymerase II transcription subunit 13 chr17 Not Cancer Driver No 1 hippie, biogrid 207 906 90 90 2
MED13L-201 MED13L Q71F56 Mediator of RNA polymerase II transcription subunit 13-like chr12 Not Cancer Driver No 1 hippie, biogrid 128 1077 73 73 0
MED14-201 MED14 O60244 Mediator of RNA polymerase II transcription subunit 14 chrX Not Cancer Driver No 1 hippie, biogrid 129 318 35 35 0
MED15-201 MED15 Q96RN5 Mediator of RNA polymerase II transcription subunit 15 chr22 Not Cancer Driver No 1 hippie, biogrid 30 558 15 15 0
MED17-201 MED17 Q9NVC6 Mediator of RNA polymerase II transcription subunit 17 chr11 Not Cancer Driver No 3 hippie, biogrid 48 185 8 8 1
MED18-201 MED18 Q9BUE0 Mediator of RNA polymerase II transcription subunit 18 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 23 10 1 1 0
MED19-202 MED19 A0JLT2 Mediator of RNA polymerase II transcription subunit 19 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 7 230 5 5 0
MED20-201 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
MED21-201 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 8 46 2 2 0
MED22-201 MED22 Q15528 Mediator of RNA polymerase II transcription subunit 22 chr9 Not Cancer Driver No 1 hippie, biogrid 18 97 10 10 0
MED24-204 MED24 O75448 Mediator of RNA polymerase II transcription subunit 24 chr17 Not Cancer Driver No 1 hippie, biogrid 77 75 0 0 0
MED26-201 MED26 O95402 Mediator of RNA polymerase II transcription subunit 26 chr19 Not Cancer Driver No 2 hippie, biogrid 49 541 44 44 0
MED27-201 MED27 Q6P2C8 Mediator of RNA polymerase II transcription subunit 27 chr9 Not Cancer Driver No 1 hippie, biogrid 17 61 3 3 0
MED28-201 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 2 hippie, biogrid 24 101 17 17 0
MED30-201 MED30 Q96HR3 Mediator of RNA polymerase II transcription subunit 30 chr8 Not Cancer Driver No 1 hippie, biogrid 17 94 8 8 0
MED31-201 MED31 Q9Y3C7 Mediator of RNA polymerase II transcription subunit 31 chr17 Not Cancer Driver No 1 hippie, biogrid 9 15 1 1 0
MED4-201 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 2 hippie, biogrid 23 161 13 13 0
MED6-201 MED6 O75586 Mediator of RNA polymerase II transcription subunit 6 chr14 Not Cancer Driver No 1 hippie, biogrid 17 79 6 6 0
MED7-201 MED7 O43513 Mediator of RNA polymerase II transcription subunit 7 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 21 132 15 15 0
MED8-203 MED8 Q96G25 Mediator of RNA polymerase II transcription subunit 8 chr1 Not Cancer Driver No 1 hippie, biogrid 20 191 15 15 0
MED9-201 MED9 Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 chr17 Not Cancer Driver No 2 hippie, biogrid 13 127 12 12 0
NEDD4-208 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 99 717 55 55 0
NELFE-202 NELFE P18615 Negative elongation factor E chr6 Not Cancer Driver No 1 hippie, biogrid 39 352 37 37 0
NEURL4-202 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 145 753 83 83 0
OFD1-201 OFD1 O75665 Centriole and centriolar satellite protein OFD1 chrX Not Cancer Driver No 1 hippie 77 476 25 25 5
PDRG1-201 PDRG1 Q9NUG6 p53 and DNA damage-regulated protein 1 chr20 Not Cancer Driver No 2 hippie, biogrid 14 46 7 7 0
PFDN2-201 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 111 10 10 0
PFN1-201 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 13 7 1 1 3
PHRF1-201 PHRF1 Q9P1Y6 PHD and RING finger domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 180 1420 144 144 0
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 7 intact, hippie, biogrid 24 160 13 13 0
PLEKHF2-201 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 18 36 0 0 0
POLR1A-201 POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 hippie, biogrid 160 365 49 49 2
POLR1B-201 POLR1B Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 chr2 Not Cancer Driver No 1 hippie, biogrid 85 69 7 7 1
POLR1C-210 POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 28 1 1 12
POLR1D-201 POLR1D P0DPB6 DNA-directed RNA polymerases I and III subunit RPAC2 chr13 Not Cancer Driver No 1 hippie, biogrid 15 88 12 12 7
POLR1E-202 POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 28 87 5 5 0
POLR2A-210 POLR2A P24928 DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 3 intact, hippie, biogrid 138 847 36 36 2
POLR2B-201 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 116 173 17 17 0
POLR2C-201 POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 26 108 9 9 0
POLR2D-201 POLR2D O15514 DNA-directed RNA polymerase II subunit RPB4 chr2 Not Cancer Driver No 4 intact, hippie, biogrid 11 55 2 2 0
POLR2E-213 POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 22 36 3 3 0
POLR2F-205 POLR2F P61218 DNA-directed RNA polymerases I, II, and III subunit RPABC2 chr22 Not Cancer Driver No 3 hippie, biogrid 10 57 4 4 0
POLR2G-201 POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 Not Cancer Driver No 6 intact, hippie, biogrid 13 15 2 2 0
POLR2H-208 POLR2H P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 16 14 2 2 0
POLR2I-201 POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 16 22 3 3 0
POLR2J-201 POLR2J P52435 DNA-directed RNA polymerase II subunit RPB11-a chr7 Not Cancer Driver No 3 intact, hippie, biogrid 9 0 0 0 0
POLR2J3-220 POLR2J3 Q9H1A7 DNA-directed RNA polymerase II subunit RPB11-b2 chr7 Not Cancer Driver No 1 hippie, biogrid 2 0 0 0 0
POLR2K-201 POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 Not Cancer Driver No 1 hippie, biogrid 8 11 1 1 0
POLR2L-201 POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 2 hippie, biogrid 10 0 0 0 0
POLR2M-201 POLR2M P0CAP2 DNA-directed RNA polymerase II subunit GRINL1A chr15 Not Cancer Driver No 4 intact, hippie, biogrid 19 302 14 14 0
POLR3A-201 POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 2 hippie, biogrid 115 113 12 12 16
POLR3B-201 POLR3B Q9NW08 DNA-directed RNA polymerase III subunit RPC2 chr12 Not Cancer Driver No 2 hippie, biogrid 113 117 14 14 14
POLR3D-201 POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 Not Cancer Driver No 1 hippie, biogrid 29 306 21 21 0
POLR3E-201 POLR3E Q9NVU0 DNA-directed RNA polymerase III subunit RPC5 chr16 Not Cancer Driver No 2 hippie, biogrid 66 308 30 30 0
POLR3H-202 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 Not Cancer Driver No 1 hippie, biogrid 19 33 4 4 0
PPP1CA-203 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie, biogrid 31 27 6 6 0
PPP1CC-201 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 3 hippie, biogrid 19 23 3 3 0
PRPF31-201 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie, biogrid 37 213 9 9 2
RAMP1-201 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 14 0 0 0 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RECQL5-201 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 Not Cancer Driver No 1 hippie, biogrid 101 499 57 57 0
RFC4-201 RFC4 P35249 Replication factor C subunit 4 chr3 Not Cancer Driver No 1 hippie, biogrid 41 50 1 1 0
RNGTT-202 RNGTT O60942 mRNA-capping enzyme chr6 Not Cancer Driver No 2 hippie, biogrid 47 112 7 7 0
RPAP3-201 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 2 hippie, biogrid 34 334 20 20 0
RPRD1A-202 RPRD1A Q96P16 Regulation of nuclear pre-mRNA domain-containing protein 1A chr18 Not Cancer Driver No 2 intact, hippie, biogrid 34 86 14 14 0
RPRD1B-201 RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 Not Cancer Driver No 5 intact, hippie, biogrid 23 156 10 10 0
RPRD2-202 RPRD2 Q5VT52 Regulation of nuclear pre-mRNA domain-containing protein 2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 131 1226 111 111 0
RUNX1-202 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 1 hippie 62 361 46 46 2
RUVBL2-206 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 2 hippie, biogrid 52 100 11 11 0
RXRG-201 RXRG P48443 Retinoic acid receptor RXR-gamma chr1 Not Cancer Driver No 1 hippie, biogrid 85 162 37 37 0
SCAF1-201 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 Not Cancer Driver No 1 hippie, biogrid 58 1310 57 57 0
SCAF4-201 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 Not Cancer Driver No 1 hippie, biogrid 37 939 23 23 0
SIRT6-202 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 24 165 6 6 0
SPRR1B-201 SPRR1B P22528 Cornifin-B chr1 Not Cancer Driver No 1 intact, hippie, biogrid 14 74 11 11 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 41 271 24 24 30
SUPT6H-201 SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 146 761 56 56 0
SYDE1-201 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 2 hippie, biogrid 52 412 25 25 0
TCP1-201 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 34 55 7 7 0
TJP2-202 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 916 80 80 1
TNFAIP6-201 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 Not Cancer Driver No 1 hippie, biogrid 48 13 5 5 0
TNIP2-201 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 28 318 21 21 0
TOPBP1-201 TOPBP1 Q92547 DNA topoisomerase 2-binding protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 121 579 43 43 0
URI1-202 URI1 O94763 Unconventional prefoldin RPB5 interactor 1 chr19 Not Cancer Driver No 3 hippie, biogrid 60 389 50 50 0
UXT-201 UXT Q9UBK9 Protein UXT chrX Not Cancer Driver No 4 intact, hippie, biogrid 15 17 1 1 0
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 67 316 45 45 1
WWP1-202 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie, biogrid 104 432 55 55 0
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 2 hippie, biogrid 87 423 46 46 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
YBX1-201 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 31 312 31 31 0
ZFC3H1-201 ZFC3H1 O60293 Zinc finger C3H1 domain-containing protein chr12 Not Cancer Driver No 2 hippie, biogrid 157 1025 92 92 0
ZNHIT2-201 ZNHIT2 Q9UHR6 Zinc finger HIT domain-containing protein 2 chr11 Not Cancer Driver No 1 hippie 24 159 13 13 0