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RPRD2-202 ,RPRD2 ,Q5VT52
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 72
  • Number of Interaction partner in hippie: 112
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTC1-201 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 90 48 14 14 11
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 116 443 38 38 144
B9D2-201 B9D2 Q9BPU9 B9 domain-containing protein 2 chr19 Not Cancer Driver No 1 intact, hippie 32 4 4 4 1
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 13 112 7 7 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CNOT9-201 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 32 30 0 0 0
CRCP-203 CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 Not Cancer Driver No 1 hippie, biogrid 8 114 4 4 0
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 intact, hippie 47 75 6 6 4
CTDSP1-201 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 Not Cancer Driver No 1 hippie 30 46 1 1 0
CTR9-201 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 intact, hippie 109 385 29 29 0
DCPS-201 DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 32 55 5 5 1
DGCR8-201 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 Census, Compendium Yes 1 hippie, biogrid 77 466 43 43 0
DHX8-201 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 Not Cancer Driver No 1 hippie, biogrid 92 490 40 40 0
DYNC1H1-201 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 intact, hippie 371 495 47 47 21
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ENST00000684631 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
GPN1-211 GPN1 Q9HCN4 GPN-loop GTPase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 25 117 8 8 0
GPN3-201 GPN3 Q9UHW5 GPN-loop GTPase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 13 19 0 0 0
H1-5-201 H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 13 226 13 13 0
HDAC2-205 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 34 145 11 11 0
HIF1AN-201 HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 2 hippie, biogrid 24 78 5 5 0
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 20 200 10 10 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 19 200 7 7 0
HSPA2-201 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 68 286 30 30 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie, biogrid 82 252 28 28 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
LEO1-201 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 intact, hippie 57 611 53 53 0
LIN28A-202 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 Not Cancer Driver No 1 intact 30 86 11 11 0
LMO2-202 LMO2 P25791 Rhombotin-2 chr11 Census Yes 2 intact, hippie, biogrid 24 14 0 0 0
MDC1-201 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 175 1829 156 156 0
MED1-201 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 1 hippie, biogrid 81 1104 50 50 0
MED10-201 MED10 Q9BTT4 Mediator of RNA polymerase II transcription subunit 10 chr5 Not Cancer Driver No 1 hippie, biogrid 15 13 3 3 0
MED14-201 MED14 O60244 Mediator of RNA polymerase II transcription subunit 14 chrX Not Cancer Driver No 1 hippie, biogrid 129 318 35 35 0
MED17-201 MED17 Q9NVC6 Mediator of RNA polymerase II transcription subunit 17 chr11 Not Cancer Driver No 1 hippie, biogrid 48 185 8 8 1
MED19-202 MED19 A0JLT2 Mediator of RNA polymerase II transcription subunit 19 chr11 Not Cancer Driver No 1 hippie, biogrid 7 230 5 5 0
MED20-201 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
MED21-201 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 1 hippie, biogrid 8 46 2 2 0
MED26-201 MED26 O95402 Mediator of RNA polymerase II transcription subunit 26 chr19 Not Cancer Driver No 1 hippie, biogrid 49 541 44 44 0
MED27-201 MED27 Q6P2C8 Mediator of RNA polymerase II transcription subunit 27 chr9 Not Cancer Driver No 1 hippie, biogrid 17 61 3 3 0
MED28-201 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 1 hippie, biogrid 24 101 17 17 0
MED4-201 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie, biogrid 23 161 13 13 0
MED8-203 MED8 Q96G25 Mediator of RNA polymerase II transcription subunit 8 chr1 Not Cancer Driver No 1 hippie, biogrid 20 191 15 15 0
MPG-201 MPG P29372 DNA-3-methyladenine glycosylase chr16 Not Cancer Driver No 1 hippie 31 143 18 18 0
MTNR1B-201 MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 1 intact, hippie 80 8 1 1 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NCBP1-202 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact, hippie 66 89 7 7 0
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 193 891 140 140 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUP50-201 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 hippie, biogrid 43 335 30 30 0
PDRG1-201 PDRG1 Q9NUG6 p53 and DNA damage-regulated protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 14 46 7 7 0
PFDN2-201 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 111 10 10 0
PHRF1-201 PHRF1 Q9P1Y6 PHD and RING finger domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 180 1420 144 144 0
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 24 160 13 13 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
POLR1A-201 POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 hippie, biogrid 160 365 49 49 2
POLR1B-201 POLR1B Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 chr2 Not Cancer Driver No 1 hippie, biogrid 85 69 7 7 1
POLR1C-210 POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 28 1 1 12
POLR1D-201 POLR1D P0DPB6 DNA-directed RNA polymerases I and III subunit RPAC2 chr13 Not Cancer Driver No 1 hippie, biogrid 15 88 12 12 7
POLR1E-202 POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 28 87 5 5 0
POLR2A-210 POLR2A P24928 DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie, biogrid 138 847 36 36 2
POLR2B-201 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 1 hippie, biogrid 116 173 17 17 0
POLR2C-201 POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 26 108 9 9 0
POLR2D-201 POLR2D O15514 DNA-directed RNA polymerase II subunit RPB4 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 11 55 2 2 0
POLR2E-213 POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 22 36 3 3 0
POLR2F-205 POLR2F P61218 DNA-directed RNA polymerases I, II, and III subunit RPABC2 chr22 Not Cancer Driver No 1 hippie, biogrid 10 57 4 4 0
POLR2G-201 POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 Not Cancer Driver No 5 intact, hippie, biogrid 13 15 2 2 0
POLR2H-208 POLR2H P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 chr3 Not Cancer Driver No 1 hippie, biogrid 16 14 2 2 0
POLR2I-201 POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 Not Cancer Driver No 1 hippie, biogrid 16 22 3 3 0
POLR2J-201 POLR2J P52435 DNA-directed RNA polymerase II subunit RPB11-a chr7 Not Cancer Driver No 2 hippie, biogrid 9 0 0 0 0
POLR2K-201 POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 Not Cancer Driver No 1 hippie, biogrid 8 11 1 1 0
POLR2L-201 POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 2 hippie, biogrid 10 0 0 0 0
POLR2M-201 POLR2M P0CAP2 DNA-directed RNA polymerase II subunit GRINL1A chr15 Not Cancer Driver No 2 intact, hippie, biogrid 19 302 14 14 0
POLR3A-201 POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 hippie, biogrid 115 113 12 12 16
POLR3B-201 POLR3B Q9NW08 DNA-directed RNA polymerase III subunit RPC2 chr12 Not Cancer Driver No 1 hippie, biogrid 113 117 14 14 14
POLR3D-201 POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 Not Cancer Driver No 1 hippie, biogrid 29 306 21 21 0
POLR3E-201 POLR3E Q9NVU0 DNA-directed RNA polymerase III subunit RPC5 chr16 Not Cancer Driver No 1 hippie, biogrid 66 308 30 30 0
POLR3H-202 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 Not Cancer Driver No 1 hippie, biogrid 19 33 4 4 0
POLR3K-201 POLR3K Q9Y2Y1 DNA-directed RNA polymerase III subunit RPC10 chr16 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 1
POTEI-201 POTEI P0CG38 POTE ankyrin domain family member I chr2 Not Cancer Driver No 1 hippie, biogrid 0 452 0 0 0
PPP1CA-203 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact, hippie 31 27 6 6 0
PPP1CC-201 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 19 23 3 3 0
RECQL5-201 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 Not Cancer Driver No 1 hippie, biogrid 101 499 57 57 0
RNGTT-202 RNGTT O60942 mRNA-capping enzyme chr6 Not Cancer Driver No 1 hippie, biogrid 47 112 7 7 0
RPA1-201 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 45 98 7 7 1
RPA2-203 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 20 117 12 12 0
RPA3-201 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 10 4 1 1 0
RPAP2-203 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 43 294 23 23 0
RPAP3-201 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 34 334 20 20 0
RPRD1A-202 RPRD1A Q96P16 Regulation of nuclear pre-mRNA domain-containing protein 1A chr18 Not Cancer Driver No 1 intact, hippie, biogrid 34 86 14 14 0
RPRD1B-201 RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 Not Cancer Driver No 4 intact, hippie, biogrid 23 156 10 10 0
RPS6KL1-216 RPS6KL1 Q9Y6S9 Ribosomal protein S6 kinase-like 1 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 53 162 15 15 0
S100A2-202 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 12 6 0 0 0
S100A4-204 S100A4 P26447 Protein S100-A4 chr1 Not Cancer Driver No 1 hippie, biogrid 6 6 1 1 0
S100A6-201 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 hippie, biogrid 5 4 0 0 0
SCAF1-201 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 Not Cancer Driver No 1 hippie, biogrid 58 1310 57 57 0
SCAF4-201 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 Not Cancer Driver No 1 hippie, biogrid 37 939 23 23 0
SIRT6-202 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 24 165 6 6 0
SMG7-201 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie 95 664 67 67 0
SP7-202 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 46 332 32 32 0
SPOP-206 SPOP O43791 Speckle-type POZ protein chr17 Census, Compendium Yes 1 hippie 136 25 1 1 6
SPTB-202 SPTB P11277 Spectrin beta chain, erythrocytic chr14 Not Cancer Driver No 1 hippie, biogrid 263 567 45 45 7
STRAP-202 STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 2 hippie, biogrid 33 40 4 4 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUPT5H-204 SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 115 574 58 58 0
SUPT6H-201 SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 146 761 56 56 0
TRIM37-201 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 89 493 42 42 3
UPF1-207 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 intact, hippie 114 330 33 33 0
URI1-202 URI1 O94763 Unconventional prefoldin RPB5 interactor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 60 389 50 50 0
UXT-201 UXT Q9UBK9 Protein UXT chrX Not Cancer Driver No 1 hippie, biogrid 15 17 1 1 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 intact, hippie 50 109 7 7 3
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
XRCC6-202 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 49 140 8 8 0