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RUNX3-201 ,RUNX3 ,Q13761
  • Number of Interaction partner in intact: 9
  • Number of Interaction partner in biogrid: 5
  • Number of Interaction partner in hippie: 53
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
BRD2-201 BRD2 P25440 Bromodomain-containing protein 2 chr6 Not Cancer Driver No 1 intact, hippie 82 632 63 63 0
BRD4-213 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 143 1184 132 132 0
BTF3-202 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 20 192 18 18 0
CBFB-201 CBFB Q13951 Core-binding factor subunit beta chr16 Census, Compendium Yes 2 hippie, biogrid 29 95 9 9 0
CCND1-201 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 1 intact, hippie 47 32 25 25 0
CIC-206 CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 216 1552 207 207 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
DZIP3-201 DZIP3 Q86Y13 E3 ubiquitin-protein ligase DZIP3 chr3 Not Cancer Driver No 1 hippie 141 372 55 55 0
EGLN1-201 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 Not Cancer Driver No 1 hippie 22 206 4 4 2
EGLN2-201 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 Not Cancer Driver No 1 hippie 36 204 9 9 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EZH2-203 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 74 284 32 32 11
FANCD2-212 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 116 182 9 9 3
FANCI-202 FANCI Q9NVI1 Fanconi anemia group I protein chr15 Not Cancer Driver No 1 hippie 103 130 15 15 2
FBXW12-201 FBXW12 Q6X9E4 F-box/WD repeat-containing protein 12 chr3 Not Cancer Driver No 1 hippie, biogrid 44 0 0 0 0
GLI1-201 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 156 1018 138 138 0
GUCD1-204 GUCD1 Q96NT3 Protein GUCD1 chr22 Not Cancer Driver No 1 intact, hippie 22 11 0 0 0
HDAC1-201 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 30 135 5 5 0
HDAC2-205 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 34 145 11 11 0
HDAC4-201 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 2 intact, hippie 145 751 95 95 3
HDAC5-213 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 93 720 61 61 0
HDAC9-212 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie 222 631 140 140 0
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 54 436 28 28 0
IKZF1-201 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 1 hippie 106 328 72 72 4
IKZF3-203 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 89 286 52 52 1
IL17A-201 IL17A Q16552 Interleukin-17A chr6 Not Cancer Driver No 1 intact 45 56 16 16 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
MEX3B-201 MEX3B Q6ZN04 RNA-binding protein MEX3B chr15 Not Cancer Driver No 1 hippie 57 439 45 45 0
MYCN-201 MYCN P04198 N-myc proto-oncogene protein chr2 Census, Compendium Yes 1 hippie 65 415 59 59 2
NANOG-201 NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 35 171 28 28 0
NHLRC2-201 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 53 103 8 8 0
NOTCH1-204 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 312 690 71 71 3
PHB2-203 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 25 26 4 4 0
PIN1-201 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 13 116 11 11 0
PML-201 PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 87 312 28 28 0
RBPJ-206 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 32 151 10 10 2
RCBTB2-201 RCBTB2 O95199 RCC1 and BTB domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 61 37 3 3 0
RUNX2-212 RUNX2 Q13950 Runt-related transcription factor 2 chr6 Not Cancer Driver No 1 hippie, biogrid 50 447 44 44 30
RYBP-201 RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 23 202 22 22 0
SIRT2-201 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 Not Cancer Driver No 1 hippie 40 85 13 13 0
SMAD1-201 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 Not Cancer Driver No 1 hippie 39 162 19 19 0
SMAD2-201 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 58 137 11 11 3
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 80 113 15 15 5
SMAD5-211 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 Not Cancer Driver No 1 hippie 25 172 6 6 0
SMURF1-201 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 60 257 19 19 0
SMURF2-201 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 Not Cancer Driver No 1 hippie 63 244 19 19 0
SP110-203 SP110 Q9HB58 Sp110 nuclear body protein chr2 Not Cancer Driver No 1 hippie 49 374 28 28 0
SUFU-202 SUFU Q9UMX1 Suppressor of fused homolog chr10 Census Yes 1 hippie 48 200 15 15 2
SUV39H1-202 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 43 15 1 1 0
TCF7-201 TCF7 P36402 Transcription factor 7 chr5 Not Cancer Driver No 1 intact, hippie 26 307 23 23 0
TCF7L2-206 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 1 intact, hippie 76 517 62 62 0
TLE1-203 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 intact, hippie 86 385 39 39 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
XCL1-201 XCL1 P47992 Lymphotactin chr1 Not Cancer Driver No 1 intact 25 35 10 10 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 41 491 41 41 0