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SH2D1B-201 ,SH2D1B ,O14796
  • Uniprot Accession= O14796
  • Ensembl Transcript= ENST00000367929.3
  • Uniprot Name= SH2D1B
  • Name= SH2 domain-containing protein 1B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 12
  • Number of Interaction partner in hippie: 47
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABLIM1-211 ABLIM1 O14639 Actin-binding LIM protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 84 381 37 37 0
AGR2-203 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 14 20 1 1 1
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
AR-201 AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 116 443 38 38 144
BLK-201 BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 intact, hippie 78 75 17 17 0
CD244-202 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 Not Cancer Driver No 1 hippie 54 93 16 16 0
CD84-201 CD84 Q9UIB8 SLAM family member 5 chr1 Not Cancer Driver No 3 intact, hippie 63 52 8 8 0
DAPP1-203 DAPP1 Q9UN19 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide chr4 Not Cancer Driver No 1 intact, hippie 28 41 5 5 0
DDIT4L-201 DDIT4L Q96D03 DNA damage-inducible transcript 4-like protein chr4 Not Cancer Driver No 1 hippie 28 5 2 2 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 346 223 30 30 1
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 2 hippie, biogrid 249 315 32 32 1
ERBB3-201 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie, biogrid 265 398 59 59 3
ERBB4-202 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 hippie, biogrid 376 324 95 95 2
FOS-201 FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 37 247 28 28 0
GAB1-201 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 54 570 46 46 1
HSPA1A-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 20 200 10 10 0
HSPA1B-201 HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 19 200 7 7 0
INPP5D-204 INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 Not Cancer Driver No 1 intact, hippie 140 579 75 75 0
KIT-201 KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie, biogrid 186 84 24 24 15
LY9-201 LY9 Q9HBG7 T-lymphocyte surface antigen Ly-9 chr1 Not Cancer Driver No 1 hippie 109 250 39 39 0
MAGEB4-201 MAGEB4 O15481 Melanoma-associated antigen B4 chrX Not Cancer Driver No 1 hippie 72 187 33 33 0
MAPK8IP2-202 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 Not Cancer Driver No 1 hippie 42 574 25 25 0
MEOX2-201 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 intact, hippie 59 275 53 53 0
MET-202 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 intact, hippie, biogrid 161 62 10 10 16
NFKBID-201 NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 1 intact, hippie 41 125 16 16 0
NUTM1-201 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 hippie 156 975 137 137 0
OLIG1-201 OLIG1 Q8TAK6 Oligodendrocyte transcription factor 1 chr21 Not Cancer Driver No 1 intact, hippie 3 130 0 0 0
PECAM1-203 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 0 153 0 0 0
PLCG1-202 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 129 187 15 15 0
PLCG2-206 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 183 144 18 18 1
PRDX1-202 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 intact, hippie 23 40 7 7 0
PRMT3-202 PRMT3 O60678 Protein arginine N-methyltransferase 3 chr11 Not Cancer Driver No 1 hippie, biogrid 50 52 7 7 0
PTK2-228 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 intact, hippie 102 426 45 45 0
PTPN18-201 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 42 138 8 8 0
ROBO1-202 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 245 1125 158 158 0
SH2D1A-202 SH2D1A O60880 SH2 domain-containing protein 1A chrX Not Cancer Driver No 1 intact, hippie 28 24 6 6 19
SIRPA-202 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 1 hippie, biogrid 60 282 41 41 0
SLAMF1-201 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 Not Cancer Driver No 2 intact, hippie 54 64 8 8 0
SLAMF6-202 SLAMF6 Q96DU3 SLAM family member 6 chr1 Not Cancer Driver No 1 hippie 59 60 10 10 0
SLAMF7-203 SLAMF7 Q9NQ25 SLAM family member 7 chr1 Not Cancer Driver No 1 intact, hippie 43 53 10 10 0
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 40 130 10 10 1
STAT4-202 STAT4 Q14765 Signal transducer and activator of transcription 4 chr2 Not Cancer Driver No 1 intact, hippie 109 143 24 24 0
TCF12-201 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 1 intact, hippie 65 683 65 65 3
TGFB1I1-203 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 Not Cancer Driver No 1 intact, hippie 49 219 27 27 0
TNK2-201 TNK2 Q07912 Activated CDC42 kinase 1 chr3 Not Cancer Driver No 1 intact, hippie 103 598 66 66 0
TRIM54-202 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 2 intact, hippie 47 98 11 11 0
WFS1-201 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 78 205 11 11 40