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SIKE1-201 ,SIKE1 ,Q9BRV8
  • Number of Interaction partner in intact: 31
  • Number of Interaction partner in biogrid: 36
  • Number of Interaction partner in hippie: 60
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI2-203 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie, biogrid 46 377 30 30 0
AGGF1-201 AGGF1 Q8N302 Angiogenic factor with G patch and FHA domains 1 chr5 Not Cancer Driver No 1 hippie 68 583 60 60 1
ALDH7A1-201 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 Not Cancer Driver No 1 hippie, biogrid 41 26 0 0 8
APEX1-201 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 23 104 9 9 0
ASH1L-201 ASH1L Q9NR48 Histone-lysine N-methyltransferase ASH1L chr1 Not Cancer Driver No 1 hippie 298 1863 184 184 1
BTD-212 BTD P43251 Biotinidase chr3 Not Cancer Driver No 1 intact, hippie 42 14 2 2 7
CBFA2T2-205 CBFA2T2 O43439 Protein CBFA2T2 chr20 Not Cancer Driver No 1 intact, hippie 70 458 45 45 0
CCDC186-203 CCDC186 Q7Z3E2 Coiled-coil domain-containing protein 186 chr10 Not Cancer Driver No 1 hippie, biogrid 48 705 42 42 0
CCDC88C-203 CCDC88C Q9P219 Protein Daple chr14 Not Cancer Driver No 1 hippie, biogrid 183 1615 147 147 1
CDC42BPB-201 CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 Not Cancer Driver No 1 hippie, biogrid 148 697 74 74 2
CENPQ-201 CENPQ Q7L2Z9 Centromere protein Q chr6 Not Cancer Driver No 1 intact, hippie 23 183 16 16 0
CTAG1A-202 CTAG1B P78358 Cancer/testis antigen 1 chrX Not Cancer Driver No 1 hippie 0 98 0 0 0
CTAG1B-201 CTAG1B P78358 Cancer/testis antigen 1 chrX Not Cancer Driver No 1 hippie 0 98 0 0 0
ELL-201 ELL P55199 RNA polymerase II elongation factor ELL chr19 Census, Compendium Yes 1 intact, hippie 48 448 37 37 0
EMD-202 EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie 29 160 18 18 3
EXOC1-203 EXOC1 Q9NV70 Exocyst complex component 1 chr4 Not Cancer Driver No 1 hippie, biogrid 83 154 14 14 0
EXOC4-201 EXOC4 Q96A65 Exocyst complex component 4 chr7 Not Cancer Driver No 1 hippie, biogrid 128 133 24 24 0
FGFR1OP2-201 FGFR1OP2 Q9NVK5 FGFR1 oncogene partner 2 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 18 188 15 15 0
ICE2-201 ICE2 Q659A1 Little elongation complex subunit 2 chr15 Not Cancer Driver No 1 intact, hippie 78 399 31 31 0
IFT20-203 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
IKBKE-203 IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 hippie 90 76 10 10 0
ISCA2-204 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 38 0 0 1
KIF2B-201 KIF2B Q8N4N8 Kinesin-like protein KIF2B chr17 Not Cancer Driver No 2 hippie, biogrid 276 189 99 99 0
MAP4K4-202 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie 60 648 29 29 0
MOB4-202 MOB4 Q9Y3A3 MOB-like protein phocein chr2 Not Cancer Driver No 4 intact, hippie, biogrid 16 34 3 3 0
MRPL58-201 MRPL58 Q14197 Large ribosomal subunit protein mL62 chr17 Not Cancer Driver No 1 intact, hippie 26 106 11 11 0
NHSL2-207 NHSL2 Q5HYW2 NHS-like protein 2 chrX Not Cancer Driver No 2 hippie, biogrid 90 1131 87 87 0
NTAQ1-201 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 24 27 3 3 0
PDCD10-201 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 25 25 3 3 0
PLP1-223 PLP1 P60201 Myelin proteolipid protein chrX Not Cancer Driver No 1 hippie, biogrid 36 5 0 0 64
PPP2CA-203 PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 4 intact, hippie 32 12 1 1 7
PPP2CB-201 PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 5 intact, hippie, biogrid 27 12 0 0 0
PPP2R1A-201 PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 4 intact, hippie, biogrid 169 0 0 0 4
PPP2R1B-206 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 2 intact, hippie 45 17 1 1 0
PSMC5-201 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 2 hippie, biogrid 35 64 5 5 0
RABEP2-202 RABEP2 Q9H5N1 Rab GTPase-binding effector protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 71 443 59 59 0
RASIP1-201 RASIP1 Q5U651 Ras-interacting protein 1 chr19 Not Cancer Driver No 1 intact, hippie 59 506 39 39 0
RASSF3-203 RASSF3 Q86WH2 Ras association domain-containing protein 3 chr12 Not Cancer Driver No 1 intact, hippie 18 60 2 2 0
S100A6-201 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 hippie, biogrid 5 4 0 0 0
SIKE1-201 SIKE1 Q9BRV8 Suppressor of IKBKE 1 chr1 Not Cancer Driver No 2 intact, hippie 17 107 8 8 0
SLMAP-224 SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 Not Cancer Driver No 5 intact, hippie, biogrid 56 466 25 25 0
STK24-201 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 Not Cancer Driver No 4 intact, hippie, biogrid 42 118 13 13 0
STK25-201 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 34 171 13 13 0
STK26-202 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 3 intact, hippie, biogrid 44 119 14 14 0
STRIP1-201 STRIP1 Q5VSL9 Striatin-interacting protein 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 76 267 22 22 0
STRIP2-201 STRIP2 Q9ULQ0 Striatin-interacting protein 2 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 87 178 18 18 0
STRN-201 STRN O43815 Striatin chr2 Census, Compendium Yes 5 intact, hippie, biogrid 63 349 33 33 0
STRN3-202 STRN3 Q13033 Striatin-3 chr14 Not Cancer Driver No 5 intact, hippie, biogrid 62 366 25 25 0
STRN4-201 STRN4 Q9NRL3 Striatin-4 chr19 Not Cancer Driver No 2 hippie, biogrid 62 409 35 35 0
STX11-201 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 51 49 5 5 0
TBK1-201 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 hippie 68 42 4 4 12
TNFRSF1A-201 TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 2 hippie, biogrid 38 111 14 14 9
TNIK-204 TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie, biogrid 126 782 86 86 0
TRAF3IP3-203 TRAF3IP3 Q9Y228 TRAF3-interacting JNK-activating modulator chr1 Not Cancer Driver No 3 hippie, biogrid 75 353 54 54 0
TRIML2-208 TRIML2 Q8N7C3 Probable E3 ubiquitin-protein ligase TRIML2 chr4 Not Cancer Driver No 2 hippie, biogrid 137 78 21 21 0
TTC1-201 TTC1 Q99614 Tetratricopeptide repeat protein 1 chr5 Not Cancer Driver No 1 intact, hippie 21 213 18 18 0
TXLNA-202 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 intact, hippie 55 481 46 46 0
TXLNB-201 TXLNB Q8N3L3 Beta-taxilin chr6 Not Cancer Driver No 1 intact, hippie 94 551 82 82 0
ZC2HC1C-203 ZC2HC1C Q53FD0 Zinc finger C2HC domain-containing protein 1C chr14 Not Cancer Driver No 2 intact, hippie, biogrid 28 399 22 22 0
ZRANB1-201 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 65 158 16 16 0
ZYG11A-201 ZYG11A Q6WRX3 Protein zyg-11 homolog A chr1 Not Cancer Driver No 1 hippie, biogrid 24 7 0 0 0