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SIPA1L2-206 ,SIPA1L2 ,Q9P2F8
  • Number of Interaction partner in intact: 2
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 106
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 96 43 5 5 4
ACTR3-201 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 24 16 2 2 0
AFDN-211 AFDN P55196 Afadin chr6 Census Yes 1 hippie 162 1247 123 123 0
AMOT-203 AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 103 911 85 85 0
ANAPC2-201 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie, biogrid 81 147 22 22 0
ANKFY1-201 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 70 186 20 20 0
AP3M1-201 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 Not Cancer Driver No 1 hippie 33 19 1 1 0
APOBEC3D-201 APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 Not Cancer Driver No 2 hippie, biogrid 28 3 0 0 0
BICD1-210 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 105 661 70 70 0
BORCS6-201 BORCS6 Q96GS4 BLOC-1-related complex subunit 6 chr17 Not Cancer Driver No 1 hippie 16 270 11 11 0
C6orf141-206 C6orf141 Q5SZD1 Uncharacterized protein C6orf141 chr6 Not Cancer Driver No 2 hippie, biogrid 7 227 6 6 0
CCDC96-201 CCDC96 Q2M329 Coiled-coil domain-containing protein 96 chr4 Not Cancer Driver No 1 hippie, biogrid 45 309 22 22 0
CCZ1-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 24 43 0 0 0
CCZ1B-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 18 43 2 2 0
CELA1-201 CELA1 Q9UNI1 Chymotrypsin-like elastase family member 1 chr12 Not Cancer Driver No 2 hippie, biogrid 30 21 0 0 0
CEP128-209 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 139 902 117 117 0
CEP135-201 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 2 hippie, biogrid 93 693 52 52 0
CEP250-202 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 192 1863 148 148 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie, biogrid 363 288 291 291 11
DDX6-206 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 2 intact, hippie, biogrid 29 129 6 6 4
DENND6A-201 DENND6A Q8IWF6 Protein DENND6A chr3 Not Cancer Driver No 1 hippie, biogrid 39 70 1 1 0
DNAJB13-201 DNAJB13 P59910 DnaJ homolog subfamily B member 13 chr11 Not Cancer Driver No 1 hippie, biogrid 42 42 11 11 1
DPPA4-201 DPPA4 Q7L190 Developmental pluripotency-associated protein 4 chr3 Not Cancer Driver No 1 hippie 76 183 39 39 0
DUSP16-202 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 55 273 26 26 0
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 3 447 1 1 0
DYRK1B-201 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 Not Cancer Driver No 2 hippie, biogrid 67 319 31 31 2
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
ENST00000381568 APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 Not Cancer Driver No 2 hippie, biogrid 28 3 0 0 0
ESR2-202 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 69 92 10 10 1
FAM184A-201 FAM184A Q8NB25 Protein FAM184A chr6 Not Cancer Driver No 1 hippie, biogrid 135 784 89 89 0
FBXW11-201 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 41 20 2 2 6
FBXW8-204 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 1 hippie 48 121 4 4 0
FERMT2-201 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 Not Cancer Driver No 1 hippie 44 102 8 8 0
FLOT1-201 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 122 10 10 0
GFAP-214 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 hippie, biogrid 45 290 27 27 41
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 62 111 20 20 43
HOOK1-201 HOOK1 Q9UJC3 Protein Hook homolog 1 chr1 Not Cancer Driver No 1 hippie 73 427 45 45 0
KCNE3-201 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 771 7 2 2 22
KRT18-201 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie, biogrid 46 179 17 17 4
KRT2-201 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie, biogrid 77 337 32 32 10
KRT8-218 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 49 225 23 23 3
LARP1-204 LARP1 Q6PKG0 La-related protein 1 chr5 Not Cancer Driver No 1 hippie 100 815 75 75 0
LATS1-207 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 2 hippie, biogrid 122 790 74 74 0
LATS2-201 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 101 690 57 57 0
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 76 95 12 12 1
LZTS1-202 LZTS1 Q9Y250 Leucine zipper putative tumor suppressor 1 chr8 Not Cancer Driver No 1 hippie, biogrid 90 471 69 69 0
LZTS2-205 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 3 hippie, biogrid 63 511 51 51 0
LZTS3-202 LZTS3 O60299 Leucine zipper putative tumor suppressor 3 chr20 Not Cancer Driver No 1 hippie, biogrid 59 569 50 50 0
MARS2-201 MARS2 Q96GW9 Methionine--tRNA ligase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 56 34 5 5 1
MAST1-201 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 160 1081 99 99 1
N4BP3-201 N4BP3 O15049 NEDD4-binding protein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 51 476 44 44 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NANOG-201 NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 35 171 28 28 0
NIN-202 NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 177 1402 121 121 2
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 193 891 140 140 0
NRSN1-204 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 41 18 6 6 0
OBSL1-204 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 168 556 38 38 0
OCLN-202 OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 44 244 18 18 1
ODF2-220 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 hippie 99 609 72 72 0
ORC5-201 ORC5 O43913 Origin recognition complex subunit 5 chr7 Not Cancer Driver No 1 hippie 27 16 2 2 0
PARD3-208 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 148 1147 128 128 2
PATL1-201 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 hippie 51 500 31 31 0
PCGF1-201 PCGF1 Q9BSM1 Polycomb group RING finger protein 1 chr2 Not Cancer Driver No 1 hippie 22 8 1 1 0
PDLIM7-202 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie, biogrid 30 247 14 14 0
PFN1-201 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 13 7 1 1 3
POMGNT2-201 POMGNT2 Q8NAT1 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 46 23 3 3 3
POU5F1-201 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 27 186 8 8 0
PRG2-201 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 3 hippie, biogrid 37 66 13 13 0
PROZ-202 PROZ P22891 Vitamin K-dependent protein Z chr13 Not Cancer Driver No 2 hippie, biogrid 35 13 4 4 0
PTPN18-201 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 42 138 8 8 0
PXN-201 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie, biogrid 41 342 14 14 0
RACGAP1-201 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 54 255 20 20 2
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 50 20 1 1 0
RNF20-202 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 Not Cancer Driver No 1 hippie, biogrid 83 563 43 43 0
RPGRIP1L-212 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 hippie 127 587 73 73 8
RPL28-201 RPL28 P46779 Large ribosomal subunit protein eL28 chr19 Not Cancer Driver No 1 hippie, biogrid 20 115 16 16 0
SAMD4B-212 SAMD4B Q5PRF9 Protein Smaug homolog 2 chr19 Not Cancer Driver No 1 hippie 68 467 47 47 0
SASS6-201 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 61 332 26 26 1
SF3B2-201 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 hippie 84 804 80 80 0
SIPA1-209 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 56 671 41 41 0
SIPA1L1-211 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 231 1176 166 166 0
SIPA1L3-201 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 228 1266 160 160 0
SNX5-201 SNX5 Q9Y5X3 Sorting nexin-5 chr20 Not Cancer Driver No 1 hippie, biogrid 22 93 8 8 0
SSX2IP-201 SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 hippie 48 265 17 17 0
STIL-202 STIL Q15468 SCL-interrupting locus protein chr1 Census, Compendium Yes 1 hippie, biogrid 106 735 64 64 1
STX7-202 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 21 165 9 9 0
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
TCEANC-208 TCEANC Q8N8B7 Transcription elongation factor A N-terminal and central domain-containing protein chrX Not Cancer Driver No 1 intact, hippie 21 140 5 5 0
TGM2-201 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 Not Cancer Driver No 1 hippie 82 108 19 19 0
TOMM22-201 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 11 83 5 5 0
TRIM52-205 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 Not Cancer Driver No 1 hippie, biogrid 11 147 5 5 0
TRIM66-208 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 32 773 20 20 0
TSPYL1-201 TSPYL1 Q9H0U9 Testis-specific Y-encoded-like protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 43 243 29 29 0
UBR1-201 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 Not Cancer Driver No 1 hippie, biogrid 122 165 13 13 17
UNC119-202 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 hippie, biogrid 14 89 5 5 1
UNC119B-201 UNC119B A6NIH7 Protein unc-119 homolog B chr12 Not Cancer Driver No 1 hippie, biogrid 25 71 2 2 0
VASP-201 VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 16 335 11 11 0
VCL-201 VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie, biogrid 83 680 60 60 2
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 67 316 45 45 1
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 hippie, biogrid 19 110 3 3 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 hippie, biogrid 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 10 55 0 0 0
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 hippie, biogrid 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 hippie, biogrid 19 81 7 7 0
ZYX-201 ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 49 385 29 29 0