Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1-207 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | Census, Compendium | Yes | 1 | intact, hippie | 37 | 360 | 28 | 28 | 0 |
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | Census, Compendium | Yes | 1 | hippie | 106 | 609 | 53 | 53 | 2 |
| ACTA1-202 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 63 | 48 | 13 | 13 | 67 |
| ADAM10-201 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 156 | 18 | 18 | 4 |
| ADD1-206 | ADD1 | P35611 | Alpha-adducin | chr4 | Not Cancer Driver | No | 1 | hippie | 63 | 440 | 39 | 39 | 0 |
| AGR2-203 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 14 | 20 | 1 | 1 | 1 |
| ANK1-205 | ANK1 | P16157 | Ankyrin-1 | chr8 | Census | Yes | 1 | hippie | 315 | 813 | 131 | 131 | 3 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 94 | 419 | 52 | 52 | 12 |
| BCKDK-201 | BCKDK | O14874 | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 44 | 39 | 2 | 2 | 3 |
| BRIP1-201 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | Census | Yes | 1 | hippie | 118 | 399 | 41 | 41 | 6 |
| BTK-201 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | Census, Compendium | Yes | 1 | hippie | 109 | 114 | 21 | 21 | 83 |
| C21orf58-201 | C21orf58 | P58505 | Uncharacterized protein C21orf58 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 306 | 22 | 22 | 0 |
| CBL-201 | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | Census, Compendium | Yes | 1 | hippie | 84 | 513 | 44 | 44 | 4 |
| CCDC185-201 | CCDC185 | Q8N715 | Coiled-coil domain-containing protein 185 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 85 | 594 | 82 | 82 | 0 |
| CEP250-202 | CEP250 | Q9BV73 | Centrosome-associated protein CEP250 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 192 | 1863 | 148 | 148 | 0 |
| CLEC4G-201 | CLEC4G | Q6UXB4 | C-type lectin domain family 4 member G | chr19 | Not Cancer Driver | No | 1 | intact | 32 | 35 | 3 | 3 | 0 |
| CUL4A-202 | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 54 | 102 | 2 | 2 | 0 |
| DCAF15-201 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 1 | hippie | 35 | 173 | 14 | 14 | 0 |
| DGCR6L-201 | DGCR6L | Q9BY27 | Protein DGCR6L | chr22 | Not Cancer Driver | No | 1 | hippie | 15 | 76 | 7 | 7 | 0 |
| EMD-202 | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 1 | hippie | 29 | 160 | 18 | 18 | 3 |
| ENAH-204 | ENAH | Q8N8S7 | Protein enabled homolog | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 27 | 514 | 27 | 27 | 0 |
| ENST00000640655 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 721 | 45 | 45 | 0 |
| EPB41L3-201 | EPB41L3 | Q9Y2J2 | Band 4.1-like protein 3 | chr18 | Not Cancer Driver | No | 1 | hippie | 240 | 697 | 165 | 165 | 0 |
| ERCC1-202 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | Not Cancer Driver | No | 1 | hippie | 36 | 107 | 14 | 14 | 1 |
| ERCC2-204 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | Census, Compendium | Yes | 1 | hippie | 103 | 5 | 0 | 0 | 30 |
| ERCC3-201 | ERCC3 | P19447 | General transcription and DNA repair factor IIH helicase subunit XPB | chr2 | Census, Compendium | Yes | 1 | hippie | 67 | 208 | 14 | 14 | 2 |
| ERCC4-201 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | Census | Yes | 1 | hippie | 81 | 226 | 19 | 19 | 15 |
| ERCC5-212 | ERCC5 | P28715 | DNA excision repair protein ERCC-5 | chr13 | Census | Yes | 1 | hippie | 115 | 819 | 78 | 78 | 6 |
| ERCC6-201 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | Not Cancer Driver | No | 1 | hippie | 142 | 837 | 82 | 82 | 9 |
| EVL-202 | EVL | Q9UI08 | Ena/VASP-like protein | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 339 | 34 | 34 | 0 |
| EXOSC5-201 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 32 | 2 | 2 | 3 |
| EZR-202 | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | hippie | 51 | 296 | 26 | 26 | 0 |
| FANCA-202 | FANCA | O15360 | Fanconi anemia group A protein | chr16 | Census, Compendium | Yes | 1 | hippie | 121 | 157 | 13 | 13 | 26 |
| FANCC-201 | FANCC | Q00597 | Fanconi anemia group C protein | chr9 | Census, Compendium | Yes | 1 | hippie | 38 | 13 | 0 | 0 | 3 |
| FANCD2-212 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 116 | 182 | 9 | 9 | 3 |
| FANCF-201 | FANCF | Q9NPI8 | Fanconi anemia group F protein | chr11 | Census, Compendium | Yes | 1 | hippie | 23 | 51 | 2 | 2 | 0 |
| FANCG-201 | FANCG | O15287 | Fanconi anemia group G protein | chr9 | Census | Yes | 1 | hippie | 43 | 48 | 1 | 1 | 1 |
| FASLG-202 | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 94 | 15 | 15 | 1 |
| GADD45GIP1-201 | GADD45GIP1 | Q8TAE8 | Large ribosomal subunit protein mL64 | chr19 | Not Cancer Driver | No | 1 | hippie | 9 | 193 | 9 | 9 | 0 |
| GAN-203 | GAN | Q9H2C0 | Gigaxonin | chr16 | Not Cancer Driver | No | 1 | hippie | 48 | 33 | 3 | 3 | 20 |
| GJA1-201 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie | 62 | 111 | 20 | 20 | 43 |
| H3-4-201 | H3-4 | Q16695 | Histone H3.1t | chr1 | Not Cancer Driver | No | 1 | intact | 25 | 53 | 7 | 7 | 0 |
| HNRNPA2B1-201 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | hippie | 35 | 255 | 13 | 13 | 1 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 129 | 16 | 2 | 2 | 10 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie | 771 | 7 | 2 | 2 | 22 |
| KRT75-201 | KRT75 | O95678 | Keratin, type II cytoskeletal 75 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 78 | 145 | 23 | 23 | 1 |
| LMNA-205 | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 50 | 547 | 34 | 34 | 117 |
| MRE11-201 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | Not Cancer Driver | No | 1 | hippie | 61 | 292 | 28 | 28 | 1 |
| MYBL2-201 | MYBL2 | P10244 | Myb-related protein B | chr20 | Not Cancer Driver | No | 1 | hippie | 74 | 511 | 53 | 53 | 0 |
| NCOA3-202 | NCOA3 | Q9Y6Q9 | Nuclear receptor coactivator 3 | chr20 | Not Cancer Driver | No | 1 | hippie | 134 | 1231 | 119 | 119 | 0 |
| NRAS-201 | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie | 272 | 10 | 0 | 0 | 12 |
| ODF3B-201 | ODF3B | A8MYP8 | Outer dense fiber protein 3B | chr22 | Not Cancer Driver | No | 1 | hippie | 9 | 184 | 3 | 3 | 0 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 88 | 322 | 28 | 28 | 0 |
| PKP2-201 | PKP2 | Q99959 | Plakophilin-2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 139 | 435 | 77 | 77 | 8 |
| PLEC-201 | PLEC | Q15149 | Plectin | chr8 | Not Cancer Driver | No | 1 | hippie | 336 | 2138 | 125 | 125 | 2 |
| PML-201 | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie | 87 | 312 | 28 | 28 | 0 |
| PTEN-201 | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | Census, Compendium | Yes | 1 | hippie | 425 | 76 | 5 | 5 | 37 |
| PTPN22-201 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | Not Cancer Driver | No | 1 | hippie | 107 | 344 | 44 | 44 | 4 |
| PTPRO-201 | PTPRO | Q16827 | Receptor-type tyrosine-protein phosphatase O | chr12 | Not Cancer Driver | No | 1 | hippie | 155 | 137 | 28 | 28 | 0 |
| RAD23B-201 | RAD23B | P54727 | UV excision repair protein RAD23 homolog B | chr9 | Not Cancer Driver | No | 1 | hippie | 29 | 326 | 24 | 24 | 0 |
| RAD50-201 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 106 | 730 | 50 | 50 | 0 |
| RAD51-201 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 27 | 48 | 3 | 3 | 3 |
| RPA1-201 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 98 | 7 | 7 | 1 |
| RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | Not Cancer Driver | No | 1 | hippie | 20 | 117 | 12 | 12 | 0 |
| RPSA-201 | RPSA | P08865 | Small ribosomal subunit protein uS2 | chr3 | Not Cancer Driver | No | 1 | hippie | 16 | 95 | 1 | 1 | 4 |
| SHC1-202 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 58 | 400 | 41 | 41 | 0 |
| SLC4A1-201 | SLC4A1 | P02730 | Band 3 anion transport protein | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 124 | 131 | 19 | 19 | 32 |
| SLC9A2-201 | SLC9A2 | Q9UBY0 | Sodium/hydrogen exchanger 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 136 | 221 | 48 | 48 | 0 |
| SMARCA2-203 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | Not Cancer Driver | No | 1 | hippie | 178 | 1015 | 100 | 100 | 36 |
| SMARCA4-201 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | Census, Compendium | Yes | 1 | hippie | 300 | 1078 | 163 | 163 | 5 |
| SNIP1-201 | SNIP1 | Q8TAD8 | Smad nuclear-interacting protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 45 | 286 | 32 | 32 | 1 |
| SPTA1-208 | SPTA1 | P02549 | Spectrin alpha chain, erythrocytic 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 888 | 714 | 248 | 248 | 17 |
| SPTB-202 | SPTB | P11277 | Spectrin beta chain, erythrocytic | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 263 | 567 | 45 | 45 | 7 |
| SPTBN1-202 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 218 | 877 | 86 | 86 | 16 |
| SPTBN2-208 | SPTBN2 | O15020 | Spectrin beta chain, non-erythrocytic 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 233 | 879 | 90 | 90 | 2 |
| SPTBN4-210 | SPTBN4 | Q9H254 | Spectrin beta chain, non-erythrocytic 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 264 | 871 | 75 | 75 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2742 | 282 | 1364 | 1364 | 60 |
| TSHZ2-201 | TSHZ2 | Q9NRE2 | Teashirt homolog 2 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 276 | 785 | 203 | 203 | 0 |
| TXN2-201 | TXN2 | Q99757 | Thioredoxin, mitochondrial | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 34 | 4 | 4 | 0 |
| UBASH3B-201 | UBASH3B | Q8TF42 | Ubiquitin-associated and SH3 domain-containing protein B | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 74 | 3 | 3 | 0 |
| UBE2A-202 | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | Compendium | Yes | 1 | hippie | 23 | 67 | 11 | 11 | 2 |
| USP11-201 | USP11 | P51784 | Ubiquitin carboxyl-terminal hydrolase 11 | chrX | Not Cancer Driver | No | 1 | hippie | 104 | 211 | 21 | 21 | 0 |
| VASP-201 | VASP | P50552 | Vasodilator-stimulated phosphoprotein | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 16 | 335 | 11 | 11 | 0 |
| XPA-201 | XPA | P23025 | DNA repair protein complementing XP-A cells | chr9 | Census | Yes | 1 | hippie | 12 | 121 | 6 | 6 | 5 |
| XRCC2-201 | XRCC2 | O43543 | DNA repair protein XRCC2 | chr7 | Not Cancer Driver | No | 1 | hippie | 27 | 9 | 0 | 0 | 2 |
| XRCC5-201 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | Not Cancer Driver | No | 1 | hippie | 53 | 119 | 6 | 6 | 0 |
| XRCC6-202 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 49 | 140 | 8 | 8 | 0 |
| YWHAQ-201 | YWHAQ | P27348 | 14-3-3 protein theta | chr2 | Not Cancer Driver | No | 1 | hippie | 23 | 41 | 2 | 2 | 0 |
| ZNF326-201 | ZNF326 | Q5BKZ1 | DBIRD complex subunit ZNF326 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 491 | 27 | 27 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|