Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA1-202 | ABCA1 | O95477 | Phospholipid-transporting ATPase ABCA1 | chr9 | Not Cancer Driver | No | 1 | hippie | 202 | 247 | 25 | 25 | 31 |
| ACE2-201 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 68 | 4 | 4 | 0 |
| ACP2-206 | ACP2 | P11117 | Lysosomal acid phosphatase | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 35 | 78 | 8 | 8 | 0 |
| ADPGK-202 | ADPGK | Q9BRR6 | ADP-dependent glucokinase | chr15 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 33 | 24 | 0 | 0 | 0 |
| ANKFY1-201 | ANKFY1 | Q9P2R3 | Rabankyrin-5 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 186 | 20 | 20 | 0 |
| ANXA11-203 | ANXA11 | P50995 | Annexin A11 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 244 | 6 | 6 | 2 |
| AQP6-201 | AQP6 | Q13520 | Aquaporin-6 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 22 | 4 | 4 | 0 |
| AQP8-201 | AQP8 | O94778 | Aquaporin-8 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 0 | 0 | 0 | 0 |
| ARF6-201 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 5 | 0 | 0 | 0 |
| ASPH-203 | ASPH | Q12797 | Aspartyl/asparaginyl beta-hydroxylase | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 374 | 33 | 33 | 1 |
| ATP4A-201 | ATP4A | P20648 | Potassium-transporting ATPase alpha chain 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 152 | 122 | 21 | 21 | 0 |
| ATP5MG-201 | ATP5MG | O75964 | ATP synthase subunit g, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 0 | 0 | 0 | 0 |
| ATP6V1B1-201 | ATP6V1B1 | P15313 | V-type proton ATPase subunit B, kidney isoform | chr2 | Not Cancer Driver | No | 1 | hippie | 60 | 67 | 7 | 7 | 9 |
| B3GAT1-201 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 93 | 24 | 24 | 0 |
| BCL2L13-201 | BCL2L13 | Q9BXK5 | Bcl-2-like protein 13 | chr22 | Not Cancer Driver | No | 1 | hippie | 32 | 291 | 18 | 18 | 0 |
| BET1-201 | BET1 | O15155 | BET1 homolog | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 7 | 2 | 2 | 0 |
| BIRC3-201 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 53 | 98 | 10 | 10 | 0 |
| BLOC1S6-201 | BLOC1S6 | Q9UL45 | Biogenesis of lysosome-related organelles complex 1 subunit 6 | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 10 | 111 | 10 | 10 | 0 |
| BNIP1-202 | BNIP1 | Q12981 | Vesicle transport protein SEC20 | chr5 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 31 | 57 | 7 | 7 | 0 |
| BZW2-201 | BZW2 | Q9Y6E2 | eIF5-mimic protein 1 | chr7 | Not Cancer Driver | No | 3 | hippie, biogrid | 31 | 59 | 6 | 6 | 0 |
| CACNA1C-220 | CACNA1C | Q13936 | Voltage-dependent L-type calcium channel subunit alpha-1C | chr12 | Not Cancer Driver | No | 1 | intact | 350 | 708 | 123 | 123 | 25 |
| CAV1-201 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 2 | 0 | 0 | 0 |
| CCDC138-201 | CCDC138 | Q96M89 | Coiled-coil domain-containing protein 138 | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 49 | 203 | 18 | 18 | 0 |
| CCR1-201 | CCR1 | P32246 | C-C chemokine receptor type 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 14 | 0 | 0 | 0 |
| CD79A-201 | CD79A | P11912 | B-cell antigen receptor complex-associated protein alpha chain | chr19 | Census | Yes | 1 | intact, hippie | 20 | 28 | 1 | 1 | 0 |
| CDC42-208 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| CFTR-201 | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | intact | 216 | 145 | 9 | 9 | 130 |
| CISD1-201 | CISD1 | Q9NZ45 | CDGSH iron-sulfur domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 4 | 18 | 0 | 0 | 0 |
| CISD2-201 | CISD2 | Q8N5K1 | CDGSH iron-sulfur domain-containing protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 6 | 7 | 0 | 0 | 0 |
| COG6-204 | COG6 | Q9Y2V7 | Conserved oligomeric Golgi complex subunit 6 | chr13 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 52 | 141 | 7 | 7 | 1 |
| DDR2-201 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | Census | Yes | 1 | biogrid | 129 | 120 | 25 | 25 | 7 |
| DNAJC5-201 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 46 | 5 | 5 | 1 |
| DPP4-201 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 8 | 0 | 0 | 0 |
| DTX2-206 | DTX2 | Q86UW9 | Probable E3 ubiquitin-protein ligase DTX2 | chr7 | Not Cancer Driver | No | 1 | hippie | 59 | 295 | 26 | 26 | 0 |
| EBP-205 | EBP | Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | chrX | Not Cancer Driver | No | 1 | intact, hippie | 22 | 9 | 0 | 0 | 7 |
| EEA1-201 | EEA1 | Q15075 | Early endosome antigen 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 104 | 1174 | 90 | 90 | 0 |
| EHD1-201 | EHD1 | Q9H4M9 | EH domain-containing protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 92 | 11 | 11 | 0 |
| EIF2B1-201 | EIF2B1 | Q14232 | Translation initiation factor eIF-2B subunit alpha | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 32 | 0 | 0 | 0 | 2 |
| EIF2B2-201 | EIF2B2 | P49770 | Translation initiation factor eIF-2B subunit beta | chr14 | Not Cancer Driver | No | 3 | hippie, biogrid | 34 | 83 | 9 | 9 | 9 |
| EIF2B3-201 | EIF2B3 | Q9NR50 | Translation initiation factor eIF-2B subunit gamma | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 38 | 28 | 7 | 7 | 5 |
| EIF2B4-201 | EIF2B4 | Q9UI10 | Translation initiation factor eIF-2B subunit delta | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 49 | 212 | 26 | 26 | 7 |
| EIF2B5-226 | EIF2B5 | Q13144 | Translation initiation factor eIF-2B subunit epsilon | chr3 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 49 | 179 | 9 | 9 | 21 |
| ELAVL1-201 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 54 | 43 | 5 | 5 | 0 |
| ENST00000498285 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 3 | 60 | 1 | 1 | 3 |
| ENST00000695856 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| EPB42-201 | EPB42 | P16452 | Protein 4.2 | chr15 | Not Cancer Driver | No | 1 | hippie | 65 | 113 | 8 | 8 | 4 |
| ERGIC3-202 | ERGIC3 | Q9Y282 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 | chr20 | Not Cancer Driver | No | 1 | hippie | 32 | 23 | 1 | 1 | 0 |
| EWSR1-206 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | hippie | 21 | 646 | 21 | 21 | 0 |
| F3-201 | F3 | P13726 | Tissue factor | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 61 | 4 | 4 | 0 |
| FAM234A-203 | FAM234A | Q9H0X4 | Protein FAM234A | chr16 | Not Cancer Driver | No | 2 | intact, hippie | 40 | 99 | 6 | 6 | 0 |
| FAM234B-201 | FAM234B | A2RU67 | Protein FAM234B | chr12 | Not Cancer Driver | No | 1 | hippie | 77 | 137 | 19 | 19 | 0 |
| FCER1G-201 | FCER1G | P30273 | High affinity immunoglobulin epsilon receptor subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 5 | 13 | 0 | 0 | 0 |
| FGFR1-214 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 92 | 231 | 26 | 26 | 69 |
| FHIP1B-202 | FHIP1B | Q8N612 | FHF complex subunit HOOK-interacting protein 1B | chr11 | Not Cancer Driver | No | 1 | intact | 97 | 420 | 42 | 42 | 0 |
| FHIP2A-202 | FHIP2A | Q5W0V3 | FHF complex subunit HOOK interacting protein 2A | chr10 | Not Cancer Driver | No | 1 | intact | 63 | 130 | 11 | 11 | 0 |
| FRMD5-202 | FRMD5 | Q7Z6J6 | FERM domain-containing protein 5 | chr15 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 48 | 134 | 14 | 14 | 2 |
| GATA3-201 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | Census, Compendium | Yes | 1 | intact | 99 | 368 | 79 | 79 | 2 |
| GJA1-201 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 111 | 20 | 20 | 43 |
| GJA8-201 | GJA8 | P48165 | Gap junction alpha-8 protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 111 | 173 | 41 | 41 | 9 |
| GOLGA2-201 | GOLGA2 | Q08379 | Golgin subfamily A member 2 | chr9 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 84 | 859 | 71 | 71 | 0 |
| GORAB-202 | GORAB | Q5T7V8 | RAB6-interacting golgin | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 285 | 35 | 35 | 0 |
| GORASP1-201 | GORASP1 | Q9BQQ3 | Golgi reassembly-stacking protein 1 | chr3 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 34 | 294 | 23 | 23 | 0 |
| GOSR1-201 | GOSR1 | O95249 | Golgi SNAP receptor complex member 1 | chr17 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 14 | 108 | 8 | 8 | 0 |
| GOSR2-232 | GOSR2 | O14653 | Golgi SNAP receptor complex member 2 | chr17 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 16 | 106 | 10 | 10 | 2 |
| HCN1-201 | HCN1 | O60741 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | chr5 | Not Cancer Driver | No | 1 | intact | 378 | 366 | 163 | 163 | 15 |
| HGS-201 | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | Not Cancer Driver | No | 1 | hippie | 83 | 535 | 62 | 62 | 0 |
| HOMER1-202 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 32 | 243 | 28 | 28 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | intact, hippie | 129 | 16 | 2 | 2 | 10 |
| HSCB-201 | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 25 | 3 | 3 | 0 |
| IFITM1-202 | IFITM1 | P13164 | Interferon-induced transmembrane protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 0 | 0 | 0 | 0 |
| IFITM3-201 | IFITM3 | Q01628 | Interferon-induced transmembrane protein 3 | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 7 | 19 | 2 | 2 | 0 |
| IL32-223 | IL32 | P24001 | Interleukin-32 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 70 | 8 | 8 | 0 |
| ITFG1-201 | ITFG1 | Q8TB96 | T-cell immunomodulatory protein | chr16 | Not Cancer Driver | No | 1 | hippie | 50 | 18 | 3 | 3 | 0 |
| KASH5-201 | KASH5 | Q8N6L0 | Protein KASH5 | chr19 | Not Cancer Driver | No | 1 | intact | 73 | 408 | 58 | 58 | 0 |
| KCNE3-201 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| KCNK3-201 | KCNK3 | O14649 | Potassium channel subfamily K member 3 | chr2 | Not Cancer Driver | No | 1 | intact | 44 | 61 | 6 | 6 | 6 |
| KDSR-212 | KDSR | Q06136 | 3-ketodihydrosphingosine reductase | chr18 | Census | Yes | 1 | hippie, biogrid | 26 | 35 | 3 | 3 | 1 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | intact, hippie, biogrid | 771 | 7 | 2 | 2 | 22 |
| LAMP1-201 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 94 | 8 | 8 | 0 |
| LAMP2-201 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 55 | 4 | 4 | 1 |
| LAMP3-201 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 223 | 34 | 34 | 0 |
| LAMTOR1-201 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 96 | 6 | 6 | 0 |
| LEPROTL1-201 | LEPROTL1 | O95214 | Leptin receptor overlapping transcript-like 1 | chr8 | Census | Yes | 1 | hippie | 0 | 0 | 0 | 0 | 0 |
| LGALS9-203 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 46 | 65 | 13 | 13 | 0 |
| LMBR1L-201 | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 4 | 0 | 0 | 0 |
| LMNA-205 | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 50 | 547 | 34 | 34 | 117 |
| LRRC4-201 | LRRC4 | Q9HBW1 | Leucine-rich repeat-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 111 | 10 | 10 | 0 |
| MAP1B-201 | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 169 | 1949 | 166 | 166 | 0 |
| MAP1LC3B-201 | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | hippie | 4 | 17 | 0 | 0 | 0 |
| MARCKS-201 | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 328 | 5 | 5 | 0 |
| MFSD6-202 | MFSD6 | Q6ZSS7 | Major facilitator superfamily domain-containing protein 6 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 58 | 252 | 15 | 15 | 0 |
| MMGT1-201 | MMGT1 | Q8N4V1 | ER membrane protein complex subunit 5 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 15 | 17 | 4 | 4 | 0 |
| MOSPD2-201 | MOSPD2 | Q8NHP6 | Motile sperm domain-containing protein 2 | chrX | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 39 | 143 | 10 | 10 | 0 |
| MOV10-203 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 90 | 103 | 6 | 6 | 0 |
| MYEF2-202 | MYEF2 | Q9P2K5 | Myelin expression factor 2 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 368 | 36 | 36 | 0 |
| MYH9-201 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | intact, hippie | 247 | 1124 | 126 | 126 | 13 |
| NAPA-201 | NAPA | P54920 | Alpha-soluble NSF attachment protein | chr19 | Not Cancer Driver | No | 4 | hippie, biogrid | 19 | 11 | 0 | 0 | 0 |
| NAPB-201 | NAPB | Q9H115 | Beta-soluble NSF attachment protein | chr20 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 20 | 29 | 2 | 2 | 0 |
| NAPG-201 | NAPG | Q99747 | Gamma-soluble NSF attachment protein | chr18 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 25 | 57 | 2 | 2 | 0 |
| NBAS-201 | NBAS | A2RRP1 | NBAS subunit of NRZ tethering complex | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 272 | 246 | 32 | 32 | 8 |
| NCAPD3-212 | NCAPD3 | P42695 | Condensin-2 complex subunit D3 | chr11 | Not Cancer Driver | No | 1 | hippie | 145 | 305 | 35 | 35 | 1 |
| NDUFS1-201 | NDUFS1 | P28331 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 40 | 3 | 3 | 2 |
| NEMP1-201 | NEMP1 | O14524 | Nuclear envelope integral membrane protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 22 | 36 | 3 | 3 | 0 |
| NMRAL1-201 | NMRAL1 | Q9HBL8 | NmrA-like family domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 28 | 14 | 2 | 2 | 0 |
| NOC4L-201 | NOC4L | Q9BVI4 | Nucleolar complex protein 4 homolog | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 50 | 41 | 2 | 2 | 0 |
| NOP14-203 | NOP14 | P78316 | Nucleolar protein 14 | chr4 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 70 | 522 | 37 | 37 | 0 |
| NPC1-201 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 113 | 25 | 0 | 0 | 135 |
| NRAS-201 | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 272 | 10 | 0 | 0 | 12 |
| NRSN1-204 | NRSN1 | Q8IZ57 | Neurensin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 18 | 6 | 6 | 0 |
| NSF-201 | NSF | P46459 | Vesicle-fusing ATPase | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 32 | 84 | 2 | 2 | 2 |
| NSG1-211 | NSG1 | P42857 | Neuronal vesicle trafficking-associated protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 25 | 29 | 6 | 6 | 0 |
| OPN4-201 | OPN4 | Q9UHM6 | Melanopsin | chr10 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 64 | 89 | 8 | 8 | 0 |
| OPTN-202 | OPTN | Q96CV9 | Optineurin | chr10 | Not Cancer Driver | No | 3 | hippie, biogrid | 47 | 475 | 40 | 40 | 6 |
| PDZK1IP1-201 | PDZK1IP1 | Q13113 | PDZK1-interacting protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 13 | 21 | 0 | 0 | 0 |
| PLEKHA4-201 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 115 | 690 | 110 | 110 | 0 |
| PLPPR2-201 | PLPPR2 | Q96GM1 | Phospholipid phosphatase-related protein type 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 32 | 55 | 2 | 2 | 0 |
| PMAIP1-202 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 2 | 23 | 1 | 1 | 0 |
| PRMT9-201 | PRMT9 | Q6P2P2 | Protein arginine N-methyltransferase 9 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 64 | 4 | 4 | 0 |
| PRNP-201 | PRNP | P04156 | Major prion protein | chr20 | Not Cancer Driver | No | 1 | hippie | 28 | 117 | 8 | 8 | 19 |
| RAB11A-201 | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 43 | 2 | 2 | 0 |
| RAB1A-203 | RAB1A | P62820 | Ras-related protein Rab-1A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 38 | 2 | 2 | 0 |
| RAB1B-201 | RAB1B | Q9H0U4 | Ras-related protein Rab-1B | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 40 | 3 | 3 | 0 |
| RAB35-201 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 26 | 1 | 1 | 0 |
| RAB3B-201 | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 26 | 6 | 6 | 0 |
| RAB4A-201 | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 32 | 8 | 8 | 0 |
| RAB5A-201 | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 67 | 9 | 9 | 0 |
| RAB5C-201 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 51 | 2 | 2 | 0 |
| RAB7A-201 | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 19 | 11 | 0 | 0 | 4 |
| RAB9A-202 | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 7 | 21 | 0 | 0 | 0 |
| RAC2-201 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 2 |
| RAC3-201 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 4 |
| RAP1B-201 | RAP1B | P61224 | Ras-related protein Rap-1b | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 14 | 2 | 2 | 0 |
| RER1-209 | RER1 | O15258 | Protein RER1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 15 | 1 | 1 | 0 |
| RHOA-202 | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 92 | 46 | 12 | 12 | 2 |
| RHOB-201 | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 20 | 1 | 1 | 0 |
| RHOH-201 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 32 | 12 | 3 | 3 | 0 |
| RHOJ-201 | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 0 |
| RHOQ-201 | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 19 | 0 | 0 | 0 | 0 |
| RHOU-201 | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 63 | 6 | 6 | 0 |
| RIC3-201 | RIC3 | Q7Z5B4 | Protein RIC-3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 284 | 41 | 41 | 0 |
| RND1-201 | RND1 | Q92730 | Rho-related GTP-binding protein Rho6 | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 9 | 1 | 1 | 0 |
| RNF13-203 | RNF13 | O43567 | E3 ubiquitin-protein ligase RNF13 | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 27 | 108 | 13 | 13 | 2 |
| RNF149-201 | RNF149 | Q8NC42 | E3 ubiquitin-protein ligase RNF149 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 30 | 103 | 12 | 12 | 0 |
| RNF4-201 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 9 | 120 | 5 | 5 | 0 |
| SCFD2-202 | SCFD2 | Q8WU76 | Sec1 family domain-containing protein 2 | chr4 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 72 | 24 | 3 | 3 | 0 |
| SCGN-201 | SCGN | O76038 | Secretagogin | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 12 | 1 | 1 | 0 |
| SEC11C-204 | SEC11C | Q9BY50 | Signal peptidase complex catalytic subunit SEC11C | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 3 | 0 | 0 | 0 |
| SEC22B-201 | SEC22B | O75396 | Vesicle-trafficking protein SEC22b | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 0 | 21 | 0 | 0 | 0 |
| SLC10A6-201 | SLC10A6 | Q3KNW5 | Sodium-dependent organic anion transporter | chr4 | Not Cancer Driver | No | 1 | hippie | 44 | 38 | 5 | 5 | 0 |
| SLC66A2-203 | SLC66A2 | Q8N2U9 | Solute carrier family 66 member 2 | chr18 | Not Cancer Driver | No | 1 | intact | 29 | 11 | 0 | 0 | 0 |
| SLC7A1-201 | SLC7A1 | P30825 | High affinity cationic amino acid transporter 1 | chr13 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 73 | 17 | 3 | 3 | 0 |
| SNAP23-201 | SNAP23 | O00161 | Synaptosomal-associated protein 23 | chr15 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 12 | 180 | 10 | 10 | 0 |
| SNAP25-201 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | Not Cancer Driver | No | 1 | hippie | 46 | 178 | 38 | 38 | 1 |
| SNAP29-201 | SNAP29 | O95721 | Synaptosomal-associated protein 29 | chr22 | Not Cancer Driver | No | 4 | hippie, biogrid | 19 | 249 | 19 | 19 | 0 |
| SNAP47-213 | SNAP47 | Q5SQN1 | Synaptosomal-associated protein 47 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 38 | 151 | 15 | 15 | 0 |
| STX10-204 | STX10 | O60499 | Syntaxin-10 | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 17 | 77 | 5 | 5 | 0 |
| STX18-201 | STX18 | Q9P2W9 | Syntaxin-18 | chr4 | Not Cancer Driver | No | 3 | hippie, biogrid | 23 | 176 | 12 | 12 | 0 |
| STX1A-201 | STX1A | Q16623 | Syntaxin-1A | chr7 | Not Cancer Driver | No | 1 | hippie | 29 | 138 | 11 | 11 | 0 |
| STX2-203 | STX2 | P32856 | Syntaxin-2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 32 | 142 | 19 | 19 | 0 |
| STX4-201 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 4 | hippie, biogrid | 39 | 153 | 16 | 16 | 0 |
| STX5-201 | STX5 | Q13190 | Syntaxin-5 | chr11 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 25 | 148 | 7 | 7 | 0 |
| STX6-201 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 25 | 78 | 9 | 9 | 0 |
| STX7-202 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 21 | 165 | 9 | 9 | 0 |
| STX8-201 | STX8 | Q9UNK0 | Syntaxin-8 | chr17 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 16 | 99 | 5 | 5 | 0 |
| STXBP5-201 | STXBP5 | Q5T5C0 | Syntaxin-binding protein 5 | chr6 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 99 | 345 | 40 | 40 | 0 |
| STXBP5L-209 | STXBP5L | Q9Y2K9 | Syntaxin-binding protein 5-like | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 276 | 293 | 81 | 81 | 0 |
| STXBP6-201 | STXBP6 | Q8NFX7 | Syntaxin-binding protein 6 | chr14 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 23 | 51 | 5 | 5 | 0 |
| TAF9-201 | TAF9 | Q16594 | Transcription initiation factor TFIID subunit 9 | chr5 | Not Cancer Driver | No | 1 | hippie | 19 | 203 | 14 | 14 | 0 |
| TBC1D15-217 | TBC1D15 | Q8TC07 | TBC1 domain family member 15 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 62 | 135 | 15 | 15 | 0 |
| TBC1D17-201 | TBC1D17 | Q9HA65 | TBC1 domain family member 17 | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 55 | 192 | 13 | 13 | 0 |
| TBK1-201 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 68 | 42 | 4 | 4 | 12 |
| TFRC-201 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 66 | 80 | 4 | 4 | 1 |
| TGOLN2-201 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 401 | 33 | 33 | 0 |
| TIMMDC1-208 | TIMMDC1 | Q9NPL8 | Complex I assembly factor TIMMDC1, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 37 | 51 | 4 | 4 | 0 |
| TLCD4-201 | TLCD4 | Q96MV1 | TLC domain-containing protein 4 | chr1 | Not Cancer Driver | No | 1 | intact | 21 | 0 | 0 | 0 | 0 |
| TM9SF4-202 | TM9SF4 | Q92544 | Transmembrane 9 superfamily member 4 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 39 | 3 | 3 | 0 |
| TMEM14B-202 | TMEM14B | Q9NUH8 | Transmembrane protein 14B | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 0 | 0 | 0 | 0 |
| TMEM167B-201 | TMEM167B | Q9NRX6 | Protein kish-B | chr1 | Not Cancer Driver | No | 1 | hippie | 5 | 0 | 0 | 0 | 0 |
| TMEM17-201 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 15 | 14 | 1 | 1 | 0 |
| TMEM216-203 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 7 | 0 | 0 | 0 | 5 |
| TMEM258-204 | TMEM258 | P61165 | Transmembrane protein 258 | chr11 | Not Cancer Driver | No | 1 | hippie | 9 | 0 | 0 | 0 | 0 |
| TMEM31-201 | TMEM31 | Q5JXX7 | Transmembrane protein 31 | chrX | Not Cancer Driver | No | 1 | hippie | 16 | 61 | 6 | 6 | 0 |
| TMEM86B-201 | TMEM86B | Q8N661 | Lysoplasmalogenase | chr19 | Not Cancer Driver | No | 1 | hippie | 14 | 1 | 0 | 0 | 0 |
| TMX2-201 | TMX2 | Q9Y320 | Thioredoxin-related transmembrane protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 34 | 40 | 5 | 5 | 3 |
| TNFRSF10B-201 | TNFRSF10B | O14763 | Tumor necrosis factor receptor superfamily member 10B | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 192 | 15 | 15 | 0 |
| TNFRSF10C-201 | TNFRSF10C | O14798 | Tumor necrosis factor receptor superfamily member 10C | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 120 | 13 | 13 | 0 |
| TRDN-201 | TRDN | Q13061 | Triadin | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 59 | 646 | 55 | 55 | 1 |
| TXLNA-202 | TXLNA | P40222 | Alpha-taxilin | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 55 | 481 | 46 | 46 | 0 |
| UBQLN2-201 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | Not Cancer Driver | No | 1 | hippie | 64 | 581 | 61 | 61 | 8 |
| USE1-201 | USE1 | Q9NZ43 | Vesicle transport protein USE1 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 27 | 102 | 19 | 19 | 0 |
| VAMP2-201 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 3 | 47 | 0 | 0 | 3 |
| VAMP3-201 | VAMP3 | Q15836 | Vesicle-associated membrane protein 3 | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 8 | 17 | 1 | 1 | 0 |
| VAMP4-201 | VAMP4 | O75379 | Vesicle-associated membrane protein 4 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 6 | 80 | 2 | 2 | 0 |
| VAMP5-201 | VAMP5 | O95183 | Vesicle-associated membrane protein 5 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 13 | 19 | 1 | 1 | 0 |
| VAMP7-202 | VAMP7 | P51809 | Vesicle-associated membrane protein 7 | chrX | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 18 | 4 | 1 | 1 | 0 |
| VAMP8-201 | VAMP8 | Q9BV40 | Vesicle-associated membrane protein 8 | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 7 | 27 | 1 | 1 | 0 |
| VDAC1-201 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 36 | 4 | 4 | 0 |
| VDAC2-203 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 9 | 1 | 1 | 0 |
| VDAC3-201 | VDAC3 | Q9Y277 | Voltage-dependent anion-selective channel protein 3 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
| VPS45-214 | VPS45 | Q9NRW7 | Vacuolar protein sorting-associated protein 45 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 58 | 3 | 3 | 2 |
| VPS50-202 | VPS50 | Q96JG6 | Syndetin | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 116 | 171 | 22 | 22 | 0 |
| VTI1A-201 | VTI1A | Q96AJ9 | Vesicle transport through interaction with t-SNAREs homolog 1A | chr10 | Census | Yes | 4 | intact, hippie, biogrid | 14 | 138 | 8 | 8 | 0 |
| VTI1B-204 | VTI1B | Q9UEU0 | Vesicle transport through interaction with t-SNAREs homolog 1B | chr14 | Not Cancer Driver | No | 3 | hippie, biogrid | 14 | 195 | 12 | 12 | 0 |
| YKT6-201 | YKT6 | O15498 | Synaptobrevin homolog YKT6 | chr7 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 11 | 21 | 1 | 1 | 0 |
| ZDHHC12-201 | ZDHHC12 | Q96GR4 | Palmitoyltransferase ZDHHC12 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 13 | 1 | 1 | 0 |
| ZKSCAN1-201 | ZKSCAN1 | P17029 | Zinc finger protein with KRAB and SCAN domains 1 | chr7 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 52 | 346 | 34 | 34 | 0 |
| ZNF219-201 | ZNF219 | Q9P2Y4 | Zinc finger protein 219 | chr14 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 32 | 629 | 28 | 28 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|