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SYNC-202 ,SYNC ,Q9H7C4
  • Number of Interaction partner in intact: 35
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 69
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA1-202 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 intact, hippie 63 48 13 13 67
APC-201 APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 2 intact, hippie, biogrid 295 2412 248 248 22
ARHGEF6-201 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 2 hippie, biogrid 106 224 28 28 0
ARHGEF7-206 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 67 302 30 30 0
ATP1A3-214 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie 151 116 21 21 41
BCR-201 BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie, biogrid 112 607 57 57 0
BICDL2-203 BICDL2 A1A5D9 BICD family-like cargo adapter 2 chr16 Not Cancer Driver No 1 hippie 34 446 33 33 0
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 31 213 13 13 0
CCDC102A-201 CCDC102A Q96A19 Coiled-coil domain-containing protein 102A chr16 Not Cancer Driver No 2 intact, hippie, biogrid 41 529 34 34 0
CCDC136-201 CCDC136 Q96JN2 Coiled-coil domain-containing protein 136 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 102 822 76 76 0
CEP250-202 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 192 1863 148 148 0
CEP55-201 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 2 hippie, biogrid 34 264 15 15 0
CPNE2-201 CPNE2 Q96FN4 Copine-2 chr16 Not Cancer Driver No 1 hippie, biogrid 45 32 3 3 0
DDX39A-201 DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 36 37 2 2 0
DES-201 DES P17661 Desmin chr2 Not Cancer Driver No 3 intact, hippie, biogrid 41 267 22 22 33
DTNA-205 DTNA Q9Y4J8 Dystrobrevin alpha chr18 Not Cancer Driver No 1 hippie 107 412 58 58 0
DUSP23-201 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 Not Cancer Driver No 1 hippie, biogrid 5 13 0 0 0
ENST00000644613 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie 151 115 21 21 39
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPS15-203 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 Census, Compendium Yes 1 hippie, biogrid 74 544 47 47 0
FGFR1OP2-201 FGFR1OP2 Q9NVK5 FGFR1 oncogene partner 2 chr12 Not Cancer Driver No 1 hippie, biogrid 18 188 15 15 0
GAN-203 GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 2 hippie, biogrid 48 33 3 3 20
GCC2-201 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 124 1000 80 80 0
GEMIN5-201 GEMIN5 Q8TEQ6 Gem-associated protein 5 chr5 Not Cancer Driver No 1 intact, hippie 108 420 36 36 4
GFAP-214 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 3 intact, hippie, biogrid 45 290 27 27 41
GIT1-201 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 48 434 26 26 0
GIT2-202 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 2 hippie, biogrid 59 494 36 36 0
GOLGA3-202 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 181 1283 156 156 0
GOLGA5-201 GOLGA5 Q8TBA6 Golgin subfamily A member 5 chr14 Census Yes 2 intact, hippie, biogrid 56 593 44 44 0
HSPE1-201 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 6 3 0 0 0
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 2 hippie, biogrid 5 301 4 4 21
INA-201 INA Q16352 Alpha-internexin chr10 Not Cancer Driver No 2 intact, hippie, biogrid 51 257 35 35 0
KIF15-201 KIF15 Q9NS87 Kinesin-like protein KIF15 chr3 Not Cancer Driver No 2 hippie, biogrid 104 820 70 70 0
KIF1B-214 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 intact, hippie 187 634 82 82 1
KLHL42-201 KLHL42 Q9P2K6 Kelch-like protein 42 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 38 57 4 4 0
KRT14-201 KRT14 P02533 Keratin, type I cytoskeletal 14 chr17 Not Cancer Driver No 1 hippie, biogrid 40 185 22 22 39
KRT16-201 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 hippie, biogrid 42 153 16 16 11
KRT23-201 KRT23 Q9C075 Keratin, type I cytoskeletal 23 chr17 Not Cancer Driver No 1 hippie, biogrid 54 260 41 41 0
KRT27-201 KRT27 Q7Z3Y8 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 1 hippie, biogrid 60 144 20 20 0
LMNA-205 LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie, biogrid 50 547 34 34 117
MAGEE1-201 MAGEE1 Q9HCI5 Melanoma-associated antigen E1 chrX Not Cancer Driver No 1 hippie, biogrid 169 529 85 85 0
MAML2-201 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 Census, Compendium Yes 1 hippie, biogrid 52 1159 54 54 0
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 74 333 42 42 6
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 2 intact, hippie, biogrid 104 593 69 69 0
NDC80-201 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 2 hippie, biogrid 58 313 34 34 0
NEFL-201 NEFL P07196 Neurofilament light polypeptide chr8 Not Cancer Driver No 2 hippie, biogrid 0 285 0 0 10
NEFM-201 NEFM P07197 Neurofilament medium polypeptide chr8 Not Cancer Driver No 2 intact, hippie, biogrid 75 768 49 49 0
NES-201 NES P48681 Nestin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 203 1485 189 189 0
PECAM1-203 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 0 153 0 0 0
PLD1-201 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 intact, hippie 126 133 21 21 1
PPA2-201 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 2 intact, hippie, biogrid 25 71 3 3 9
PPL-201 PPL O60437 Periplakin chr16 Not Cancer Driver No 1 hippie, biogrid 160 1143 100 100 0
PRPH-201 PRPH P41219 Peripherin chr12 Not Cancer Driver No 2 intact, hippie, biogrid 37 242 20 20 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 20 67 9 9 0
RABEP1-202 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 Census, Compendium Yes 2 hippie, biogrid 47 520 31 31 0
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 126 220 23 23 0
RUFY1-201 RUFY1 Q96T51 RUN and FYVE domain-containing protein 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 57 358 29 29 0
SLMAP-224 SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 Not Cancer Driver No 2 intact, hippie, biogrid 56 466 25 25 0
SPDL1-201 SPDL1 Q96EA4 Protein Spindly chr5 Not Cancer Driver No 1 hippie, biogrid 59 343 34 34 0
SYNM-202 SYNM O15061 Synemin chr15 Not Cancer Driver No 2 hippie, biogrid 110 1259 91 91 0
TAB1-201 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 62 233 23 23 0
THAP11-201 THAP11 Q96EK4 THAP domain-containing protein 11 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 19 208 15 15 0
TJAP1-204 TJAP1 Q5JTD0 Tight junction-associated protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 62 445 55 55 0
TNIP1-211 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 62 628 60 60 0
TRAF3IP1-201 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 Not Cancer Driver No 1 intact, hippie 46 512 33 33 3
TUBGCP5-205 TUBGCP5 Q96RT8 Gamma-tubulin complex component 5 chr15 Not Cancer Driver No 1 hippie, biogrid 83 159 8 8 0
UACA-201 UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 Not Cancer Driver No 2 intact, hippie, biogrid 110 867 67 67 0
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 4 intact, hippie, biogrid 67 316 45 45 1
WFS1-201 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 78 205 11 11 40