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SYT6-209 ,SYT6 ,Q5T7P8
  • Number of Interaction partner in intact: 25
  • Number of Interaction partner in biogrid: 81
  • Number of Interaction partner in hippie: 119
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AEN-201 AEN Q8WTP8 Apoptosis-enhancing nuclease chr15 Not Cancer Driver No 1 intact, hippie 26 185 17 17 0
AHCYL1-202 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 41 109 11 11 0
AHCYL2-201 AHCYL2 Q96HN2 Adenosylhomocysteinase 3 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 57 209 12 12 0
AK4-201 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 16 24 2 2 0
ALCAM-201 ALCAM Q13740 CD166 antigen chr3 Not Cancer Driver No 1 hippie, biogrid 66 97 12 12 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ARL8A-201 ARL8A Q96BM9 ADP-ribosylation factor-like protein 8A chr1 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
ATP6V0A2-201 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 Not Cancer Driver No 1 hippie, biogrid 65 36 5 5 0
BCAP31-201 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 27 104 13 13 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
CCDC136-201 CCDC136 Q96JN2 Coiled-coil domain-containing protein 136 chr7 Not Cancer Driver No 1 hippie 102 822 76 76 0
CCDC57-202 CCDC57 Q2TAC2 Coiled-coil domain-containing protein 57 chr17 Not Cancer Driver No 1 intact, hippie 79 604 44 44 0
CETN3-201 CETN3 O15182 Centrin-3 chr5 Not Cancer Driver No 1 hippie, biogrid 8 19 1 1 0
CKAP5-210 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 hippie, biogrid 149 634 48 48 0
CLPP-201 CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 15 83 7 7 3
CNTROB-202 CNTROB Q8N137 Centrobin chr17 Not Cancer Driver No 1 intact, hippie 72 843 71 71 0
CSE1L-201 CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie, biogrid 77 32 4 4 0
CSTF3-201 CSTF3 Q12996 Cleavage stimulation factor subunit 3 chr11 Not Cancer Driver No 1 hippie, biogrid 60 123 12 12 0
CTBP2-205 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 36 94 4 4 0
CYB5R3-201 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 8
DIS3-201 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 Compendium Yes 1 hippie, biogrid 72 236 18 18 0
DNM2-201 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie, biogrid 95 271 32 32 16
DVL3-201 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 Not Cancer Driver No 2 intact, hippie 58 437 31 31 0
EDC4-201 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 109 702 56 56 0
EHD4-201 EHD4 Q9H223 EH domain-containing protein 4 chr15 Not Cancer Driver No 1 hippie, biogrid 39 98 7 7 0
F11R-202 F11R Q9Y624 Junctional adhesion molecule A chr1 Not Cancer Driver No 1 hippie, biogrid 42 72 12 12 0
FAM162A-203 FAM162A Q96A26 Protein FAM162A chr3 Not Cancer Driver No 1 hippie, biogrid 10 53 4 4 0
FXR1-202 FXR1 P51114 RNA-binding protein FXR1 chr3 Not Cancer Driver No 1 intact, hippie 63 312 40 40 0
FXR2-201 FXR2 P51116 RNA-binding protein FXR2 chr17 Not Cancer Driver No 2 intact, hippie 45 388 29 29 0
GALE-216 GALE Q14376 UDP-glucose 4-epimerase chr1 Not Cancer Driver No 1 hippie, biogrid 25 24 2 2 16
GAPDH-201 GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie, biogrid 36 24 3 3 0
GLRX3-201 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 32 24 1 1 0
GMCL1-201 GMCL1 Q96IK5 Germ cell-less protein-like 1 chr2 Not Cancer Driver No 1 intact, hippie 23 80 2 2 0
GOLGA2-201 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 2 intact, hippie 84 859 71 71 0
GSTK1-201 GSTK1 Q9Y2Q3 Glutathione S-transferase kappa 1 chr7 Not Cancer Driver No 1 hippie, biogrid 28 30 3 3 0
HDGFL2-208 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 26 622 26 26 0
HDLBP-201 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie, biogrid 143 555 61 61 0
HMBOX1-201 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 36 319 28 28 0
HMOX2-208 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 17 74 5 5 0
HOOK2-202 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact, hippie 70 489 49 49 0
HTT-201 HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 261 668 51 51 2
IDH2-201 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 51 61 0 0 4
KANK2-201 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 88 534 59 59 3
KCTD9-201 KCTD9 Q7L273 BTB/POZ domain-containing protein KCTD9 chr8 Not Cancer Driver No 2 intact, hippie 32 27 0 0 0
KIF24-202 KIF24 Q5T7B8 Kinesin-like protein KIF24 chr9 Not Cancer Driver No 1 intact, hippie 95 903 62 62 0
KIFC3-201 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 1 intact, hippie 60 488 34 34 0
KRT40-201 KRT40 Q6A162 Keratin, type I cytoskeletal 40 chr17 Not Cancer Driver No 1 intact, hippie 50 7 2 2 0
LARS2-209 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 57 80 6 6 3
LETM1-201 LETM1 O95202 Mitochondrial proton/calcium exchanger protein chr4 Not Cancer Driver No 1 hippie, biogrid 52 289 19 19 4
LIG1-201 LIG1 P18858 DNA ligase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 99 400 50 50 3
LMNA-205 LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 50 547 34 34 117
LZTS1-202 LZTS1 Q9Y250 Leucine zipper putative tumor suppressor 1 chr8 Not Cancer Driver No 1 intact, hippie 90 471 69 69 0
MAD1L1-201 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie 82 526 55 55 0
MADD-201 MADD Q8WXG6 MAP kinase-activating death domain protein chr11 Not Cancer Driver No 3 intact, hippie, biogrid 164 726 65 65 4
MAP4K4-202 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 60 648 29 29 0
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie, biogrid 32 49 3 3 0
MCC-201 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 104 593 69 69 0
MCTS1-202 MCTS1 Q9ULC4 Malignant T-cell-amplified sequence 1 chrX Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
MIPEP-201 MIPEP Q99797 Mitochondrial intermediate peptidase chr13 Not Cancer Driver No 1 hippie, biogrid 57 40 1 1 3
MTUS2-206 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 hippie 308 1216 290 290 0
NAA15-201 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 Not Cancer Driver No 1 hippie, biogrid 61 115 15 15 0
NAA50-201 NAA50 Q9GZZ1 N-alpha-acetyltransferase 50 chr3 Not Cancer Driver No 1 hippie, biogrid 12 14 1 1 0
NCAPD2-201 NCAPD2 Q15021 Condensin complex subunit 1 chr12 Not Cancer Driver No 1 hippie, biogrid 88 345 26 26 0
NRXN1-209 NRXN1 Q9ULB1 Neurexin-1 chr2 Not Cancer Driver No 1 hippie 456 302 94 94 0
NSDHL-201 NSDHL Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating chrX Not Cancer Driver No 1 hippie, biogrid 46 39 5 5 3
PBK-201 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 Not Cancer Driver No 1 hippie, biogrid 16 92 6 6 0
PDS5A-201 PDS5A Q29RF7 Sister chromatid cohesion protein PDS5 homolog A chr4 Not Cancer Driver No 1 hippie, biogrid 101 295 28 28 0
PRKCB-201 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 153 148 26 26 0
PRPF40A-213 PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie, biogrid 39 695 29 29 0
PRPS1-204 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 16
PTGES2-202 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 Not Cancer Driver No 1 hippie, biogrid 25 30 1 1 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 36 141 17 17 0
PTPN11-201 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie, biogrid 92 260 27 27 44
PTRH2-201 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 7 19 1 1 1
PUS7-202 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 49 163 15 15 1
RAB14-201 RAB14 P61106 Ras-related protein Rab-14 chr9 Not Cancer Driver No 1 hippie, biogrid 10 41 3 3 0
RAB1B-201 RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 Not Cancer Driver No 1 hippie, biogrid 18 40 3 3 0
RAB21-201 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 Not Cancer Driver No 1 hippie, biogrid 15 59 4 4 0
RAP1B-201 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie, biogrid 20 14 2 2 0
RDH11-201 RDH11 Q8TC12 Retinol dehydrogenase 11 chr14 Not Cancer Driver No 1 hippie, biogrid 18 2 0 0 0
RMDN1-201 RMDN1 Q96DB5 Regulator of microtubule dynamics protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 19 17 0 0 0
RNF40-201 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 Not Cancer Driver No 1 hippie, biogrid 102 645 70 70 0
RPRD1B-201 RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 Not Cancer Driver No 1 hippie, biogrid 23 156 10 10 0
SAR1B-201 SAR1B Q9Y6B6 GTP-binding protein SAR1b chr5 Not Cancer Driver No 1 hippie, biogrid 13 4 0 0 5
SCARB2-201 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 46 13 3 3 1
SFXN1-201 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 21 29 0 0 0
SLC29A1-206 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 Not Cancer Driver No 1 hippie, biogrid 38 27 3 3 0
SND1-201 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie, biogrid 97 258 33 33 0
SRPRA-201 SRPRA P08240 Signal recognition particle receptor subunit alpha chr11 Not Cancer Driver No 1 hippie 76 233 33 33 0
STK25-201 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 hippie, biogrid 34 171 13 13 0
STXBP2-201 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 56 81 12 12 4
SUPT5H-204 SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 115 574 58 58 0
SYT10-201 SYT10 Q6XYQ8 Synaptotagmin-10 chr12 Not Cancer Driver No 1 hippie, biogrid 128 164 47 47 0
SYT3-206 SYT3 Q9BQG1 Synaptotagmin-3 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 101 268 37 37 0
SYT6-209 SYT6 Q5T7P8 Synaptotagmin-6 chr1 Not Cancer Driver No 1 hippie 63 137 12 12 0
TBRG4-201 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 56 61 1 1 0
TKFC-201 TKFC Q3LXA3 Triokinase/FMN cyclase chr11 Not Cancer Driver No 1 hippie 45 93 9 9 2
TMEM70-201 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 17 24 1 1 1
TMPRSS11E-201 TMPRSS11E Q9UL52 Transmembrane protease serine 11E chr4 Not Cancer Driver No 1 hippie, biogrid 81 35 8 8 0
TNIP1-211 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 1 intact, hippie 62 628 60 60 0
TNPO3-201 TNPO3 Q9Y5L0 Transportin-3 chr7 Not Cancer Driver No 1 hippie, biogrid 95 12 1 1 1
TNS2-201 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 intact, hippie 97 800 47 47 0
TOMM22-201 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 11 83 5 5 0
TRAF2-201 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 intact, hippie 51 4 1 1 0
TRIM27-202 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie 46 87 9 9 0
TRIM32-203 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 hippie 62 87 9 9 3
TSFM-212 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 21 74 4 4 2
TSGA10-203 TSGA10 Q9BZW7 Testis-specific gene 10 protein chr2 Not Cancer Driver No 1 hippie 81 478 57 57 0
TYMP-201 TYMP P19971 Thymidine phosphorylase chr22 Not Cancer Driver No 1 hippie, biogrid 21 144 6 6 5
UQCRQ-203 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 1 hippie, biogrid 8 12 1 1 1
USO1-204 USO1 O60763 General vesicular transport factor p115 chr4 Not Cancer Driver No 1 hippie, biogrid 51 370 19 19 0
VAMP3-201 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 8 17 1 1 0
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie, biogrid 55 99 7 7 1
VRK1-201 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 Not Cancer Driver No 1 hippie, biogrid 34 80 4 4 0
VTA1-202 VTA1 Q9NP79 Vacuolar protein sorting-associated protein VTA1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 33 152 19 19 0
YES1-201 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 48 63 9 9 0
ZBTB43-202 ZBTB43 O43298 Zinc finger and BTB domain-containing protein 43 chr9 Not Cancer Driver No 1 hippie 45 253 26 26 0
ZBTB8A-202 ZBTB8A Q96BR9 Zinc finger and BTB domain-containing protein 8A chr1 Not Cancer Driver No 1 intact, hippie 32 205 18 18 0
ZMPSTE24-201 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 46 23 0 0 3