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THBS3-201 ,THBS3 ,P49746
  • Number of Interaction partner in intact: 36
  • Number of Interaction partner in biogrid: 68
  • Number of Interaction partner in hippie: 75
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APBB1-220 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 80 400 43 43 0
ARHGEF1-203 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 100 457 54 54 0
ASCC3-204 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 202 87 7 7 0
BBS2-201 BBS2 Q9BXC9 Bardet-Biedl syndrome 2 protein chr16 Not Cancer Driver No 1 hippie, biogrid 60 76 8 8 20
BBS7-201 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 Not Cancer Driver No 1 hippie, biogrid 69 56 4 4 4
BDH1-203 BDH1 Q02338 D-beta-hydroxybutyrate dehydrogenase, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 35 15 1 1 0
BLVRA-201 BLVRA P53004 Biliverdin reductase A chr7 Not Cancer Driver No 3 intact, hippie, biogrid 27 6 1 1 0
BORA-202 BORA Q6PGQ7 Protein aurora borealis chr13 Not Cancer Driver No 1 hippie, biogrid 39 390 23 23 0
C5orf34-201 C5orf34 Q96MH7 Uncharacterized protein C5orf34 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 46 109 11 11 0
CALR-201 CALR P27797 Calreticulin chr19 Census Yes 1 hippie 28 245 16 16 0
CCT2-201 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 intact, hippie, biogrid 51 46 4 4 0
CCT7-201 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie, biogrid 45 36 3 3 0
CCZ1-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 3 hippie, biogrid 24 43 0 0 0
CCZ1B-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 3 hippie, biogrid 18 43 2 2 0
CORO7-201 CORO7 P57737 Coronin-7 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 82 347 29 29 0
CORO7-PAM16-202 CORO7 P57737 Coronin-7 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 101 397 37 37 0
CPS1-201 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 300 73 18 18 123
CWF19L1-201 CWF19L1 Q69YN2 CWF19-like protein 1 chr10 Not Cancer Driver No 2 hippie, biogrid 34 70 4 4 0
DDX11-229 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 95 282 32 32 1
DIP2A-202 DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 Not Cancer Driver No 3 intact, hippie, biogrid 139 399 36 36 0
DLST-202 DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie 33 192 23 23 1
DNAJA3-201 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 44 152 19 19 0
DNM3-201 DNM3 Q9UQ16 Dynamin-3 chr1 Not Cancer Driver No 1 hippie, biogrid 112 257 21 21 0
FANCB-206 FANCB Q8NB91 Fanconi anemia group B protein chrX Not Cancer Driver No 3 intact, hippie, biogrid 71 24 3 3 0
FDXR-201 FDXR P22570 NADPH:adrenodoxin oxidoreductase, mitochondrial chr17 Not Cancer Driver No 3 intact, hippie, biogrid 56 104 10 10 4
GTPBP6-201 GTPBP6 O43824 Putative GTP-binding protein 6 chrX Not Cancer Driver No 2 hippie, biogrid 25 117 1 1 0
HASPIN-201 HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 46 376 13 13 0
HPS3-201 HPS3 Q969F9 BLOC-2 complex member HPS3 chr3 Not Cancer Driver No 1 hippie, biogrid 83 51 5 5 1
HSPD1-202 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 45 83 1 1 2
INTS11-208 INTS11 Q5TA45 Integrator complex subunit 11 chr1 Not Cancer Driver No 1 hippie 57 24 1 1 0
IQSEC2-218 IQSEC2 Q5JU85 IQ motif and SEC7 domain-containing protein 2 chrX Not Cancer Driver No 3 intact, hippie, biogrid 119 1140 69 69 5
LRWD1-201 LRWD1 Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 46 133 9 9 0
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 74 333 42 42 6
MCM9-209 MCM9 Q9NXL9 DNA helicase MCM9 chr6 Not Cancer Driver No 3 hippie, biogrid 39 525 8 8 0
METTL13-201 METTL13 Q8N6R0 eEF1A lysine and N-terminal methyltransferase chr1 Not Cancer Driver No 1 biogrid 80 77 14 14 0
MKS1-202 MKS1 Q9NXB0 Tectonic-like complex member MKS1 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 59 153 18 18 2
MTO1-201 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 Not Cancer Driver No 3 hippie, biogrid 51 61 2 2 1
MTPAP-201 MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 Not Cancer Driver No 3 intact, hippie, biogrid 50 138 14 14 1
NDUFA3-214 NDUFA3 O95167 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 chr19 Not Cancer Driver No 1 hippie, biogrid 4 27 2 2 0
NEK7-202 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 1 intact, hippie 18 23 0 0 0
NOL11-201 NOL11 Q9H8H0 Nucleolar protein 11 chr17 Not Cancer Driver No 1 hippie, biogrid 53 54 6 6 0
NSUN2-201 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 Not Cancer Driver No 1 hippie, biogrid 73 222 13 13 1
PC-203 PC P11498 Pyruvate carboxylase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 144 172 20 20 9
PCCA-202 PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 78 42 8 8 16
PDE7A-203 PDE7A Q13946 High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A chr8 Not Cancer Driver No 3 intact, hippie, biogrid 33 30 5 5 0
PEX1-201 PEX1 O43933 Peroxisomal ATPase PEX1 chr7 Not Cancer Driver No 1 hippie, biogrid 98 304 22 22 17
PEX6-202 PEX6 Q13608 Peroxisomal ATPase PEX6 chr6 Not Cancer Driver No 3 hippie, biogrid 59 178 8 8 9
PIK3C2A-206 PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 Not Cancer Driver No 1 hippie, biogrid 119 351 24 24 0
PKN2-203 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 Not Cancer Driver No 1 hippie, biogrid 76 415 29 29 0
PLD2-201 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie, biogrid 71 98 5 5 0
PPOX-202 PPOX P50336 Protoporphyrinogen oxidase chr1 Not Cancer Driver No 1 hippie, biogrid 32 34 4 4 49
RAD21-201 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 3 intact, hippie, biogrid 84 421 56 56 3
RAD51C-201 RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 Not Cancer Driver No 1 hippie, biogrid 39 18 2 2 6
RFC1-202 RFC1 P35251 Replication factor C subunit 1 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 80 676 42 42 0
RIC8B-203 RIC8B Q9NVN3 Synembryn-B chr12 Not Cancer Driver No 1 hippie, biogrid 43 118 14 14 0
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 99 232 31 31 3
RPL23-206 RPL23 P62829 Large ribosomal subunit protein uL14 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 11 29 2 2 0
RTEL1-205 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 Not Cancer Driver No 1 hippie, biogrid 106 479 50 50 15
SH3BP4-202 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 Not Cancer Driver No 3 hippie, biogrid 114 243 36 36 0
SLC25A6-201 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 intact, hippie, biogrid 29 0 0 0 0
SMG8-201 SMG8 Q8ND04 Nonsense-mediated mRNA decay factor SMG8 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 110 415 45 45 1
TBC1D2B-201 TBC1D2B Q9UPU7 TBC1 domain family member 2B chr15 Not Cancer Driver No 1 hippie, biogrid 77 420 31 31 0
THBS1-201 THBS1 P07996 Thrombospondin-1 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 153 321 50 50 0
THBS2-206 THBS2 P35442 Thrombospondin-2 chr6 Not Cancer Driver No 1 hippie 197 320 53 53 0
THBS3-201 THBS3 P49746 Thrombospondin-3 chr1 Not Cancer Driver No 1 hippie 79 283 15 15 0
THBS4-201 THBS4 P35443 Thrombospondin-4 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 99 282 33 33 0
TIGD5-201 TIGD5 Q53EQ6 Tigger transposable element-derived protein 5 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 40 350 19 19 0
TOP2A-201 TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 3 intact, hippie, biogrid 115 509 46 46 0
TRMT44-201 TRMT44 Q8IYL2 Probable tRNA (uracil-O(2)-)-methyltransferase chr4 Not Cancer Driver No 2 hippie, biogrid 43 261 11 11 0
TRO-201 TRO Q12816 Trophinin chrX Not Cancer Driver No 3 hippie, biogrid 152 593 43 43 0
TTLL5-202 TTLL5 Q6EMB2 Tubulin polyglutamylase TTLL5 chr14 Not Cancer Driver No 1 hippie, biogrid 127 694 65 65 1
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 2 intact, hippie, biogrid 45 52 6 6 6
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 3 intact, hippie, biogrid 50 39 2 2 4
TUBB3-201 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 2 intact, hippie, biogrid 51 54 6 6 10
TUBB8-206 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 3 intact, hippie, biogrid 77 53 13 13 14
UTP4-201 UTP4 Q969X6 U3 small nucleolar RNA-associated protein 4 homolog chr16 Not Cancer Driver No 1 hippie 43 34 4 4 0