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TP53BP2-201 ,TP53BP2 ,Q13625
  • Number of Interaction partner in intact: 118
  • Number of Interaction partner in biogrid: 53
  • Number of Interaction partner in hippie: 223
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 96 43 5 5 4
ADAMTS12-203 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 Not Cancer Driver No 1 intact, hippie 433 375 112 112 0
AFDN-211 AFDN P55196 Afadin chr6 Census Yes 1 hippie 162 1247 123 123 0
ALB-201 ALB P02768 Albumin chr4 Compendium Yes 1 intact 127 6 0 0 2
AMOT-203 AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 2 intact, hippie, biogrid 103 911 85 85 0
AMOTL2-202 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 69 744 68 68 0
ANXA1-201 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 intact, hippie 36 61 7 7 0
APC2-206 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 Not Cancer Driver No 1 hippie 86 1739 61 61 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 2 intact, hippie 94 419 52 52 12
APPL1-201 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 35 293 18 18 1
ARHGAP45-201 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 Not Cancer Driver No 1 intact 85 684 52 52 0
ARHGEF6-201 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 1 intact, hippie 106 224 28 28 0
ATG5-204 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 33 25 6 6 1
ATPAF2-206 ATPAF2 Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 chr17 Not Cancer Driver No 1 hippie 20 66 3 3 1
ATXN7-220 ATXN7 O15265 Ataxin-7 chr3 Not Cancer Driver No 1 hippie 65 802 53 53 0
AXIN1-201 AXIN1 O15169 Axin-1 chr16 Census, Compendium Yes 1 intact, hippie 91 623 69 69 4
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 13 112 7 7 0
BAG3-201 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 30 572 30 30 7
BAIAP2-202 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 1 hippie 60 332 43 43 0
BCAS2-201 BCAS2 O75934 Pre-mRNA-splicing factor SPF27 chr1 Not Cancer Driver No 1 hippie 23 55 4 4 0
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 Census, Compendium Yes 2 intact, hippie 21 73 5 5 0
BCL2L1-201 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 intact, hippie 22 55 2 2 0
BCL2L2-201 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 Not Cancer Driver No 1 hippie 14 34 2 2 0
BECN1-213 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 36 190 15 15 0
C1orf216-201 C1orf216 Q8TAB5 UPF0500 protein C1orf216 chr1 Not Cancer Driver No 1 intact 15 200 15 15 0
CCDC13-201 CCDC13 Q8IYE1 Coiled-coil domain-containing protein 13 chr3 Not Cancer Driver No 1 intact, hippie 84 588 71 71 0
CCDC57-202 CCDC57 Q2TAC2 Coiled-coil domain-containing protein 57 chr17 Not Cancer Driver No 1 intact, hippie 79 604 44 44 0
CCDC85A-201 CCDC85A Q96PX6 Coiled-coil domain-containing protein 85A chr2 Not Cancer Driver No 1 hippie, biogrid 114 403 92 92 0
CCDC85B-201 CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 Not Cancer Driver No 1 intact, hippie 3 81 2 2 0
CCDC85C-201 CCDC85C A6NKD9 Coiled-coil domain-containing protein 85C chr14 Not Cancer Driver No 1 intact, hippie 3 305 3 3 0
CCDC92-201 CCDC92 Q53HC0 Coiled-coil domain-containing protein 92 chr12 Not Cancer Driver No 1 hippie 46 301 37 37 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 60 621 46 46 0
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CENPJ-201 CENPJ Q9HC77 Centromere protein J chr13 Not Cancer Driver No 1 intact, hippie 120 1180 108 108 1
CEP104-202 CEP104 O60308 Centrosomal protein of 104 kDa chr1 Not Cancer Driver No 1 hippie 82 307 31 31 0
CEP120-201 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 70 449 35 35 1
CEP128-209 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 139 902 117 117 0
CEP135-201 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 hippie 93 693 52 52 0
CEP152-202 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 128 990 74 74 2
CEP162-202 CEP162 Q5TB80 Centrosomal protein of 162 kDa chr6 Not Cancer Driver No 1 intact, hippie 121 1061 97 97 0
CEP44-206 CEP44 Q9C0F1 Centrosomal protein of 44 kDa chr4 Not Cancer Driver No 1 hippie 34 143 13 13 0
CEP55-201 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 1 hippie 34 264 15 15 0
CEP89-201 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 1 hippie 67 542 44 44 0
CEP95-202 CEP95 Q96GE4 Centrosomal protein of 95 kDa chr17 Not Cancer Driver No 1 intact, hippie 69 528 46 46 0
CEP97-201 CEP97 Q8IW35 Centrosomal protein of 97 kDa chr3 Not Cancer Driver No 1 hippie 63 405 28 28 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CGN-201 CGN Q9P2M7 Cingulin chr1 Not Cancer Driver No 1 intact, hippie 113 1182 111 111 0
CNTRL-205 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 166 1560 115 115 0
CNTROB-202 CNTROB Q8N137 Centrobin chr17 Not Cancer Driver No 1 intact, hippie 72 843 71 71 0
CPVL-201 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 Not Cancer Driver No 1 intact, hippie 53 0 0 0 0
CREBBP-201 CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 217 1801 91 91 30
CRELD2-201 CRELD2 Q6UXH1 Protein disulfide isomerase CRELD2 chr22 Not Cancer Driver No 1 intact 33 34 5 5 0
CRK-201 CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 24 197 19 19 0
CSNK2B-203 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 18 19 0 0 3
CTNNA1-201 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie, biogrid 90 268 25 25 4
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 2 hippie, biogrid 363 288 291 291 11
CWF19L2-201 CWF19L2 Q2TBE0 CWF19-like protein 2 chr11 Not Cancer Driver No 1 hippie 97 619 64 64 0
DCUN1D1-201 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 Not Cancer Driver No 1 hippie 24 13 1 1 0
DDX6-206 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 intact, hippie 29 129 6 6 4
DIRAS1-201 DIRAS1 O95057 GTP-binding protein Di-Ras1 chr19 Not Cancer Driver No 1 intact, hippie 32 32 4 4 0
DYNLT1-203 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
EEF1A1-201 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 98 100 10 10 0
EFHC1-201 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 Not Cancer Driver No 1 intact, hippie 55 78 11 11 17
ELOA-204 ELOA Q14241 Elongin-A chr1 Not Cancer Driver No 1 intact, hippie 50 604 40 40 0
EMILIN1-201 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 hippie, biogrid 89 671 50 50 1
ENST00000648550 CCDC13 Q8IYE1 Coiled-coil domain-containing protein 13 chr3 Not Cancer Driver No 1 intact, hippie 85 610 74 74 0
ENTR1-202 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 Not Cancer Driver No 1 hippie 43 270 30 30 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPS15L1-201 EPS15L1 Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 chr19 Not Cancer Driver No 1 hippie, biogrid 82 603 57 57 0
FAM168A-201 FAM168A Q92567 Protein FAM168A chr11 Not Cancer Driver No 1 hippie, biogrid 15 141 10 10 0
FBF1-205 FBF1 Q8TES7 Fas-binding factor 1 chr17 Not Cancer Driver No 1 hippie 106 1072 101 101 0
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 intact, biogrid 92 231 26 26 69
FRMD6-201 FRMD6 Q96NE9 FERM domain-containing protein 6 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 80 196 25 25 0
GCC1-201 GCC1 Q96CN9 GRIP and coiled-coil domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 83 511 48 48 0
GEM-201 GEM P55040 GTP-binding protein GEM chr8 Not Cancer Driver No 1 hippie 52 97 14 14 0
GFAP-214 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 intact, hippie 45 290 27 27 41
GLI1-201 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 156 1018 138 138 0
GOLGA1-202 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 68 585 51 51 0
GPS2-201 GPS2 Q13227 G protein pathway suppressor 2 chr17 Not Cancer Driver No 1 intact, hippie 20 320 18 18 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 21 10 0 0 0
H1-2-201 H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 28 214 28 28 0
H2BC9-201 H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 30 79 10 10 0
HAP1-201 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 56 463 37 37 0
HHEX-201 HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 Not Cancer Driver No 1 hippie 13 193 12 12 0
HIF1AN-201 HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 24 78 5 5 0
HNRNPUL1-204 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie 59 535 22 22 0
HOMER1-202 HOMER1 Q86YM7 Homer protein homolog 1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 32 243 28 28 0
HSF2BP-201 HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 intact, hippie 27 23 0 0 1
HSPA2-201 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 68 286 30 30 0
HSPA4-201 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 intact, hippie 50 352 21 21 0
HSPH1-201 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 1 intact, hippie 69 323 31 31 0
INSYN2A-202 INSYN2A Q6ZSG2 Inhibitory synaptic factor 2A chr10 Not Cancer Driver No 1 intact 62 398 51 51 0
IQUB-201 IQUB Q8NA54 IQ and ubiquitin-like domain-containing protein chr7 Not Cancer Driver No 1 intact, hippie 110 156 25 25 0
IRS4-202 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 intact, hippie 98 801 80 80 0
ITCH-201 ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 Not Cancer Driver No 1 hippie 75 335 33 33 0
KDM1A-201 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 48 291 21 21 3
KIF5A-202 KIF5A Q12840 Kinesin heavy chain isoform 5A chr12 Not Cancer Driver No 1 hippie, biogrid 147 569 84 84 12
KRT19-201 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 Not Cancer Driver No 1 hippie, biogrid 42 165 18 18 0
LATS1-207 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 1 hippie, biogrid 122 790 74 74 0
LATS2-201 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 101 690 57 57 0
LHX4-201 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 Not Cancer Driver No 1 intact, hippie 57 220 33 33 4
LMNB1-201 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 intact, hippie 39 407 27 27 4
LMNB2-201 LMNB2 Q03252 Lamin-B2 chr19 Not Cancer Driver No 1 intact, hippie 50 428 32 32 5
LMO4-202 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 29 11 1 1 0
LURAP1-201 LURAP1 Q96LR2 Leucine rich adaptor protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 20 169 13 13 0
MAGI1-202 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 173 1181 140 140 0
MAPK8IP2-202 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 Not Cancer Driver No 1 hippie 42 574 25 25 0
MED4-201 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie 23 161 13 13 0
MIB1-201 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie 96 284 26 26 1
MOS-201 MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 Not Cancer Driver No 1 intact, hippie 69 16 2 2 0
MPDZ-202 MPDZ O75970 Multiple PDZ domain protein chr9 Not Cancer Driver No 1 hippie, biogrid 207 861 88 88 0
MRPL20-201 MRPL20 Q9BYC9 Large ribosomal subunit protein bL20m chr1 Not Cancer Driver No 1 intact, hippie, biogrid 16 0 0 0 0
MTMR14-201 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 45 150 6 6 2
MTURN-201 MTURN Q8N3F0 Maturin chr7 Not Cancer Driver No 1 intact, hippie 9 27 3 3 0
MYBPHL-201 MYBPHL A2RUH7 Myosin-binding protein H-like chr1 Not Cancer Driver No 1 intact 26 85 5 5 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NAE1-201 NAE1 Q13564 NEDD8-activating enzyme E1 regulatory subunit chr16 Not Cancer Driver No 1 hippie 27 69 2 2 0
NAP1L2-201 NAP1L2 Q9ULW6 Nucleosome assembly protein 1-like 2 chrX Not Cancer Driver No 1 intact 93 178 43 43 0
NDC80-201 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 2 hippie, biogrid 58 313 34 34 0
NEDD4-208 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 99 717 55 55 0
NFKB1-205 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 hippie 62 345 30 30 0
NHSL2-207 NHSL2 Q5HYW2 NHS-like protein 2 chrX Not Cancer Driver No 1 intact, hippie 90 1131 87 87 0
NIN-202 NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 177 1402 121 121 2
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 intact, hippie 193 891 140 140 0
NUP153-201 NUP153 P49790 Nuclear pore complex protein Nup153 chr6 Not Cancer Driver No 1 hippie 125 1149 101 101 0
NUTF2-201 NUTF2 P61970 Nuclear transport factor 2 chr16 Not Cancer Driver No 1 hippie 16 6 2 2 0
NUTM1-201 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 hippie 156 975 137 137 0
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OCLN-202 OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 44 244 18 18 1
ODF2-220 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 intact, hippie 99 609 72 72 0
OFD1-201 OFD1 O75665 Centriole and centriolar satellite protein OFD1 chrX Not Cancer Driver No 1 hippie 77 476 25 25 5
OTUB2-201 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 Not Cancer Driver No 1 hippie 22 0 0 0 0
P4HA3-201 P4HA3 Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 44 17 1 1 0
PALS1-201 PALS1 Q8N3R9 Protein PALS1 chr14 Not Cancer Driver No 1 intact 50 338 21 21 0
PARD3-208 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 3 intact, hippie, biogrid 148 1147 128 128 2
PARD6A-201 PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 Not Cancer Driver No 1 intact, hippie 23 178 11 11 0
PARD6B-201 PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 1 intact, hippie 41 166 18 18 0
PCM1-201 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 2 intact, hippie, biogrid 104 1673 94 94 0
PHF1-202 PHF1 O43189 PHD finger protein 1 chr6 Not Cancer Driver No 1 hippie 47 277 23 23 0
PIBF1-201 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 Not Cancer Driver No 1 intact, hippie 66 420 30 30 3
PLEC-201 PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 intact, hippie 336 2138 125 125 2
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PLEKHF2-201 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 18 36 0 0 0
PLEKHN1-203 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 Not Cancer Driver No 2 intact, hippie 51 376 35 35 0
PLK1-201 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 68 120 14 14 0
POLR2L-201 POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 1 hippie 10 0 0 0 0
PPHLN1-223 PPHLN1 Q8NEY8 Periphilin-1 chr12 Not Cancer Driver No 1 hippie 53 449 52 52 0
PPP1CA-203 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 10 intact, hippie, biogrid 31 27 6 6 0
PPP1CB-202 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 4 intact, hippie 33 25 4 4 4
PPP1CC-201 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 12 intact, hippie, biogrid 19 23 3 3 0
PPP1R2-206 PPP1R2 P41236 Protein phosphatase inhibitor 2 chr3 Not Cancer Driver No 1 intact, hippie 15 207 15 15 0
PPP1R3A-201 PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 Not Cancer Driver No 1 hippie 328 812 258 258 1
PPP1R7-201 PPP1R7 Q15435 Protein phosphatase 1 regulatory subunit 7 chr2 Not Cancer Driver No 1 hippie 37 78 17 17 0
PRAM1-201 PRAM1 Q96QH2 PML-RARA-regulated adapter molecule 1 chr19 Not Cancer Driver No 1 intact, hippie 82 637 82 82 0
PRKAB2-201 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 1 intact, hippie 20 111 8 8 0
PRKCI-201 PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie 79 120 12 12 0
PRPF19-201 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 43 110 12 12 0
PRPF31-201 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 37 213 9 9 2
PRPH-201 PRPH P41219 Peripherin chr12 Not Cancer Driver No 1 hippie, biogrid 37 242 20 20 0
PTN-201 PTN P21246 Pleiotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 27 51 6 6 0
PYGO1-201 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 Not Cancer Driver No 1 intact 40 364 36 36 0
RAB3C-201 RAB3C Q96E17 Ras-related protein Rab-3C chr5 Not Cancer Driver No 1 intact 38 54 11 11 0
RALBP1-202 RALBP1 Q15311 RalA-binding protein 1 chr18 Not Cancer Driver No 1 hippie 46 381 32 32 0
RAN-212 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 18 14 0 0 0
RASAL3-201 RASAL3 Q86YV0 RAS protein activator like-3 chr19 Not Cancer Driver No 1 intact, hippie 86 540 52 52 0
RASSF10-201 RASSF10 A6NK89 Ras association domain-containing protein 10 chr11 Not Cancer Driver No 2 intact, hippie 0 373 0 0 0
RASSF7-202 RASSF7 Q02833 Ras association domain-containing protein 7 chr11 Not Cancer Driver No 4 intact, hippie, biogrid 26 280 19 19 0
RASSF8-218 RASSF8 Q8NHQ8 Ras association domain-containing protein 8 chr12 Not Cancer Driver No 6 intact, hippie, biogrid 35 207 14 14 0
RASSF9-201 RASSF9 O75901 Ras association domain-containing protein 9 chr12 Not Cancer Driver No 1 hippie 58 131 17 17 0
RELA-202 RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 53 401 32 32 0
RGMA-201 RGMA Q96B86 Repulsive guidance molecule A chr15 Not Cancer Driver No 1 intact, hippie 40 105 12 12 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact 64 420 31 31 0
RPGRIP1-202 RPGRIP1 Q96KN7 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 chr14 Not Cancer Driver No 1 intact, hippie 142 683 74 74 6
RPGRIP1L-212 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 127 587 73 73 8
RPS6-204 RPS6 P62753 Small ribosomal subunit protein eS6 chr9 Not Cancer Driver No 1 hippie, biogrid 22 150 15 15 0
RXRB-201 RXRB P28702 Retinoic acid receptor RXR-beta chr6 Not Cancer Driver No 1 hippie 36 279 13 13 0
SCLT1-201 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 intact, hippie 72 401 49 49 0
SCNM1-202 SCNM1 Q9BWG6 Sodium channel modifier 1 chr1 Not Cancer Driver No 1 intact, hippie 24 173 17 17 1
SETD5-202 SETD5 Q9C0A6 Histone-lysine N-methyltransferase SETD5 chr3 Not Cancer Driver No 1 hippie 129 1131 103 103 1
SGF29-201 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 2 intact, hippie 25 132 12 12 0
SH3KBP1-205 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 intact, hippie 65 532 49 49 0
SH3RF1-201 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 Not Cancer Driver No 1 hippie 83 588 55 55 0
SHTN1-202 SHTN1 A0MZ66 Shootin-1 chr10 Census Yes 1 intact, hippie 52 471 42 42 0
SIAH1-203 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 Not Cancer Driver No 1 hippie 22 28 2 2 5
SIAH2-201 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 Not Cancer Driver No 1 hippie 34 68 2 2 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 41 271 24 24 30
SRGAP3-202 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 3 intact, hippie, biogrid 166 551 87 87 0
SSX2IP-201 SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 2 intact, hippie 48 265 17 17 0
STAM2-201 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 hippie, biogrid 49 292 25 25 0
STX4-201 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 39 153 16 16 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUMO3-201 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 6 86 4 4 0
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 hippie 37 302 25 25 0
TARS3-201 TARS3 A2RTX5 Threonine--tRNA ligase 2, cytoplasmic chr15 Not Cancer Driver No 1 intact 60 78 3 3 0
TBC1D22B-201 TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 3 intact, hippie 43 206 23 23 0
TCL1A-201 TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 Census Yes 1 hippie 28 5 1 1 0
TCTE1-202 TCTE1 Q5JU00 Dynein regulatory complex subunit 5 chr6 Not Cancer Driver No 1 hippie 73 126 16 16 0
TJP1-201 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie, biogrid 143 1350 113 113 0
TJP2-202 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 916 80 80 1
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 7 intact, hippie 2742 282 1364 1364 60
TP53BP2-201 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 Not Cancer Driver No 1 intact, hippie 106 866 83 83 0
TP63-201 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 intact, hippie 198 398 120 120 21
TP73-208 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 intact, hippie 67 446 45 45 0
TRAF4-201 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 Not Cancer Driver No 1 hippie 33 27 1 1 0
TROAP-201 TROAP Q12815 Tastin chr12 Not Cancer Driver No 1 intact, hippie 80 649 72 72 0
TSGA10-203 TSGA10 Q9BZW7 Testis-specific gene 10 protein chr2 Not Cancer Driver No 1 hippie 81 478 57 57 0
TXLNA-202 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 2 intact, hippie 55 481 46 46 0
TYK2-204 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 1 intact, hippie 118 213 20 20 0
UBASH3A-202 UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 Not Cancer Driver No 2 intact, hippie 87 27 7 7 0
UBASH3B-201 UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 intact, hippie 62 74 3 3 0
UBE3A-228 UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 intact, hippie 90 136 16 16 0
UBTD1-201 UBTD1 Q9HAC8 Ubiquitin domain-containing protein 1 chr10 Not Cancer Driver No 1 intact, hippie 22 125 5 5 0
UNC119-202 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 intact, hippie, biogrid 14 89 5 5 1
USP4-201 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 Not Cancer Driver No 1 hippie, biogrid 80 287 21 21 0
UTP14A-201 UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie, biogrid 63 629 56 56 0
VASP-201 VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 16 335 11 11 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WWP1-202 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie 104 432 55 55 0
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 2 hippie, biogrid 87 423 46 46 0
WWTR1-201 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 Census Yes 1 hippie 29 389 29 29 0
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 4 intact, hippie, biogrid 41 491 41 41 0
YES1-201 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 48 63 9 9 0
YOD1-201 YOD1 Q5VVQ6 Ubiquitin thioesterase OTU1 chr1 Not Cancer Driver No 1 intact, hippie 19 121 3 3 0
YWHAB-201 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 intact, hippie, biogrid 19 110 3 3 0
YWHAE-201 YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 2 intact, hippie 24 41 1 1 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 4 intact, hippie, biogrid 21 78 4 4 3
YWHAH-201 YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 5 intact, hippie, biogrid 10 55 0 0 0
YWHAQ-201 YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 intact, hippie 23 41 2 2 0
YWHAZ-207 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 4 intact, hippie 19 81 7 7 0
ZBTB4-202 ZBTB4 Q9P1Z0 Zinc finger and BTB domain-containing protein 4 chr17 Not Cancer Driver No 1 intact, hippie 90 792 70 70 0
ZFP91-201 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 Not Cancer Driver No 1 intact, hippie 74 384 52 52 0
ZFP91-CNTF-201 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 Not Cancer Driver No 1 intact, hippie 70 352 48 48 0
ZGPAT-201 ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 Not Cancer Driver No 3 intact, hippie 64 347 42 42 0
ZNF26-201 ZNF26 P17031 Zinc finger protein 26 chr12 Not Cancer Driver No 1 hippie 0 60 0 0 0
ZNF438-205 ZNF438 Q7Z4V0 Zinc finger protein 438 chr10 Not Cancer Driver No 1 intact, hippie 94 614 71 71 0
ZNF552-201 ZNF552 Q9H707 Zinc finger protein 552 chr19 Not Cancer Driver No 1 intact, hippie 36 99 4 4 0
ZNF575-201 ZNF575 Q86XF7 Zinc finger protein 575 chr19 Not Cancer Driver No 1 intact, hippie 10 157 7 7 0
ZYX-201 ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 49 385 29 29 0