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TRAF5-201 ,TRAF5 ,O00463
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 7
  • Number of Interaction partner in hippie: 92
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AHCYL1-202 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 41 109 11 11 0
BEX3-203 BEX3 Q00994 Protein BEX3 chrX Not Cancer Driver No 1 hippie 15 98 13 13 0
CAMLG-201 CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 Not Cancer Driver No 1 hippie 23 158 13 13 0
CAPNS1-201 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 1 hippie 21 59 5 5 0
CCDC184-201 CCDC184 Q52MB2 Coiled-coil domain-containing protein 184 chr12 Not Cancer Driver No 1 hippie 15 185 15 15 0
CCDC40-204 CCDC40 Q4G0X9 Coiled-coil domain-containing protein 40 chr17 Not Cancer Driver No 2 hippie, biogrid 144 675 90 90 0
CD27-201 CD27 P26842 CD27 antigen chr12 Not Cancer Driver No 1 hippie 24 92 10 10 1
CD40-202 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 Not Cancer Driver No 1 hippie 32 57 6 6 2
CDC37-201 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 43 214 29 29 0
CDC40-201 CDC40 O60508 Pre-mRNA-processing factor 17 chr6 Not Cancer Driver No 1 hippie 56 214 18 18 1
CIB3-201 CIB3 Q96Q77 Calcium and integrin-binding family member 3 chr19 Not Cancer Driver No 1 hippie 42 3 1 1 0
COG5-201 COG5 Q9UP83 Conserved oligomeric Golgi complex subunit 5 chr7 Not Cancer Driver No 1 hippie 77 76 14 14 0
COG7-201 COG7 P83436 Conserved oligomeric Golgi complex subunit 7 chr16 Not Cancer Driver No 2 hippie, biogrid 71 60 6 6 0
COMMD3-201 COMMD3 Q9UBI1 COMM domain-containing protein 3 chr10 Not Cancer Driver No 1 hippie 12 2 0 0 0
DGKH-202 DGKH Q86XP1 Diacylglycerol kinase eta chr13 Not Cancer Driver No 1 hippie 105 329 37 37 0
DHX58-201 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 Not Cancer Driver No 1 hippie 50 84 7 7 0
EIF2AK2-201 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 1 hippie 36 188 15 15 1
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ENOX2-201 ENOX2 Q16206 Ecto-NOX disulfide-thiol exchanger 2 chrX Not Cancer Driver No 1 hippie 83 239 33 33 0
FAM9A-201 FAM9A Q8IZU1 Protein FAM9A chrX Not Cancer Driver No 1 hippie 35 333 35 35 0
FBXO28-201 FBXO28 Q9NVF7 F-box only protein 28 chr1 Not Cancer Driver No 2 hippie, biogrid 28 230 15 15 1
GAS8-201 GAS8 O95995 Dynein regulatory complex subunit 4 chr16 Not Cancer Driver No 1 hippie 39 234 23 23 1
GOLGA2-201 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie 84 859 71 71 0
GORASP2-201 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 hippie 42 288 24 24 0
HOMER1-202 HOMER1 Q86YM7 Homer protein homolog 1 chr5 Not Cancer Driver No 3 hippie, biogrid 32 243 28 28 0
HSD17B10-201 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 hippie 18 15 3 3 11
HSF2BP-201 HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 hippie 27 23 0 0 1
LAMP2-201 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie 29 55 4 4 1
LMO4-202 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 29 11 1 1 0
LNX1-201 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 90 261 33 33 0
LTBR-201 LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 Not Cancer Driver No 1 hippie 31 202 16 16 0
LZTS2-205 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie, biogrid 63 511 51 51 0
MAP3K14-201 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 hippie 0 543 0 0 0
MAP3K5-201 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 146 244 23 23 0
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 74 333 42 42 6
MAVS-202 MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie 55 415 44 44 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
MEOX2-201 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 hippie 59 275 53 53 0
NFATC2IP-201 NFATC2IP Q8NCF5 NFATC2-interacting protein chr16 Not Cancer Driver No 1 hippie 33 331 23 23 0
NGFR-201 NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 Not Cancer Driver No 1 hippie 46 174 23 23 0
NMI-201 NMI Q13287 N-myc-interactor chr2 Not Cancer Driver No 1 hippie 22 107 8 8 0
NUMBL-201 NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 1 hippie 34 468 20 20 0
ODF2-220 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 hippie 99 609 72 72 0
PHYH-201 PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 Not Cancer Driver No 1 hippie 34 41 2 2 14
PIAS2-204 PIAS2 O75928 E3 SUMO-protein ligase PIAS2 chr18 Not Cancer Driver No 1 hippie 57 209 19 19 0
PIBF1-201 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 Not Cancer Driver No 1 hippie 66 420 30 30 3
PICK1-201 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie 36 49 1 1 0
PSMA1-201 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 hippie 33 51 7 7 0
RAD23A-203 RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie 41 284 34 34 0
RIPK1-201 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 1 hippie 59 277 28 28 1
RIPK2-201 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 hippie 43 143 14 14 0
RNF111-202 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 Not Cancer Driver No 1 hippie 76 859 65 65 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RORC-201 RORC P51449 Nuclear receptor ROR-gamma chr1 Not Cancer Driver No 1 hippie 81 187 31 31 1
SDCBP-201 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 23 17 1 1 0
SEC13-202 SEC13 P55735 Protein SEC13 homolog chr3 Not Cancer Driver No 1 hippie 26 36 4 4 0
SERPINB9-201 SERPINB9 P50453 Serpin B9 chr6 Not Cancer Driver No 1 hippie 51 22 2 2 0
SPRED1-201 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie 53 195 28 28 2
SRSF1-201 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie 27 199 23 23 0
STIP1-201 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 54 270 28 28 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TANK-202 TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 2 hippie, biogrid 37 302 25 25 0
TBK1-201 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 hippie 68 42 4 4 12
TDP2-202 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 Not Cancer Driver No 1 hippie 38 80 4 4 0
THAP1-201 THAP1 Q9NVV9 THAP domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie 11 76 4 4 40
THAP7-201 THAP7 Q9BT49 THAP domain-containing protein 7 chr22 Not Cancer Driver No 1 hippie 27 215 21 21 0
TICAM1-201 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 Not Cancer Driver No 1 hippie 75 445 50 50 1
TNFRSF11A-202 TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 Not Cancer Driver No 1 hippie 61 286 33 33 5
TNFRSF12A-201 TNFRSF12A Q9NP84 Tumor necrosis factor receptor superfamily member 12A chr16 Not Cancer Driver No 1 hippie 7 0 0 0 0
TNFRSF13B-201 TNFRSF13B O14836 Tumor necrosis factor receptor superfamily member 13B chr17 Not Cancer Driver No 1 hippie 42 109 17 17 4
TNFRSF14-201 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 Census, Compendium Yes 1 hippie 26 54 4 4 0
TNFRSF17-201 TNFRSF17 Q02223 Tumor necrosis factor receptor superfamily member 17 chr16 Census Yes 1 hippie 17 1 0 0 0
TNFRSF19-202 TNFRSF19 Q9NS68 Tumor necrosis factor receptor superfamily member 19 chr13 Not Cancer Driver No 1 hippie 52 103 12 12 0
TNFRSF4-201 TNFRSF4 P43489 Tumor necrosis factor receptor superfamily member 4 chr1 Not Cancer Driver No 1 hippie 19 94 10 10 1
TNFRSF8-201 TNFRSF8 P28908 Tumor necrosis factor receptor superfamily member 8 chr1 Not Cancer Driver No 1 hippie 76 290 29 29 0
TNFRSF9-201 TNFRSF9 Q07011 Tumor necrosis factor receptor superfamily member 9 chr1 Not Cancer Driver No 1 hippie 34 29 9 9 0
TRAF2-201 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 hippie 51 4 1 1 0
TRAF3-202 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 1 hippie 49 101 8 8 1
TRAF3IP2-201 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 Not Cancer Driver No 1 hippie 47 413 34 34 2
TRAF5-201 TRAF5 O00463 TNF receptor-associated factor 5 chr1 Not Cancer Driver No 1 hippie 46 59 4 4 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 51 62 5 5 0
TRAIP-201 TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 Not Cancer Driver No 1 hippie 42 240 22 22 1
TRIM27-202 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 hippie 46 87 9 9 0
TRIM37-201 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 89 493 42 42 3
TRIM8-209 TRIM8 Q9BZR9 E3 ubiquitin-protein ligase TRIM8 chr10 Not Cancer Driver No 1 hippie 52 209 23 23 0
UBE2O-201 UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 hippie 94 717 54 54 0
USP25-201 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 Not Cancer Driver No 1 hippie 89 356 39 39 0
USP7-201 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 hippie 135 215 34 34 7
YPEL5-201 YPEL5 P62699 Protein yippee-like 5 chr2 Not Cancer Driver No 1 hippie 13 10 3 3 0
ZFAND6-201 ZFAND6 Q6FIF0 AN1-type zinc finger protein 6 chr15 Not Cancer Driver No 1 hippie 23 140 15 15 0
ZMYND11-203 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 Not Cancer Driver No 1 hippie 49 184 19 19 0
ZNF655-201 ZNF655 Q8N720 Zinc finger protein 655 chr7 Not Cancer Driver No 1 hippie 35 202 12 12 0