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TTC4-201 ,TTC4 ,O95801
  • Number of Interaction partner in intact: 31
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 85
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAD11-201 ACAD11 Q709F0 Acyl-CoA dehydrogenase family member 11 chr3 Not Cancer Driver No 1 intact, hippie 77 33 5 5 0
ACTR1A-201 ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie, biogrid 34 14 0 0 0
AHSA1-201 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie 33 147 14 14 0
APPL1-201 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 35 293 18 18 1
ATG2A-201 ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact 175 891 104 104 0
AURKA-208 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie, biogrid 25 180 17 17 0
BTBD2-201 BTBD2 Q9BX70 BTB/POZ domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 34 118 1 1 0
CDC37-201 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 intact, hippie 43 214 29 29 0
CDC37L1-201 CDC37L1 Q7L3B6 Hsp90 co-chaperone Cdc37-like 1 chr9 Not Cancer Driver No 1 intact, hippie 27 123 8 8 0
CDC6-201 CDC6 Q99741 Cell division control protein 6 homolog chr17 Not Cancer Driver No 1 intact, hippie 48 170 15 15 1
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CHAMP1-201 CHAMP1 Q96JM3 Chromosome alignment-maintaining phosphoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 72 628 53 53 0
CHORDC1-201 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 Not Cancer Driver No 2 hippie, biogrid 37 119 12 12 0
CHP1-201 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 Not Cancer Driver No 1 intact 22 70 13 13 0
CTPS1-217 CTPS1 P17812 CTP synthase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 43 83 4 4 0
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 54 102 2 2 0
DDI2-202 DDI2 Q5TDH0 Protein DDI1 homolog 2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 187 24 24 0
DIAPH1-201 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 Not Cancer Driver No 1 hippie, biogrid 46 692 20 20 1
DLD-201 DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 55 17 0 0 10
EDRF1-202 EDRF1 Q3B7T1 Erythroid differentiation-related factor 1 chr10 Not Cancer Driver No 4 intact, hippie, biogrid 91 270 19 19 0
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EP300-201 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 203 1792 84 84 1
EPB41L5-201 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 68 315 32 32 0
FAM120C-202 FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 127 511 66 66 0
FBXO32-203 FBXO32 Q969P5 F-box only protein 32 chr8 Not Cancer Driver No 1 hippie 31 0 0 0 1
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 25 27 3 3 0
FGFR3-205 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, biogrid 134 241 18 18 32
FKBP5-201 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 intact, hippie 47 150 15 15 0
GCC2-201 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 124 1000 80 80 0
GFER-201 GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 Not Cancer Driver No 1 biogrid 9 97 3 3 1
GIP-201 GIP P09681 Gastric inhibitory polypeptide chr17 Not Cancer Driver No 1 hippie, biogrid 33 68 14 14 0
GLE1-201 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 hippie 49 300 25 25 3
GRK6-201 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie, biogrid 43 68 8 8 0
HAT1-201 HAT1 O14929 Histone acetyltransferase type B catalytic subunit chr2 Not Cancer Driver No 1 hippie, biogrid 33 14 1 1 0
HDLBP-201 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie, biogrid 143 555 61 61 0
HGH1-201 HGH1 Q9BTY7 Protein HGH1 homolog chr8 Not Cancer Driver No 4 intact, hippie, biogrid 3 106 1 1 0
HGS-201 HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 83 535 62 62 0
HLA-A-203 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 intact 38 125 16 16 0
HPS5-201 HPS5 Q9UPZ3 BLOC-2 complex member HPS5 chr11 Not Cancer Driver No 1 hippie, biogrid 76 237 11 11 2
HSCB-201 HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 2 intact, hippie, biogrid 23 25 3 3 0
HSP90AA1-201 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 2 intact, hippie 44 258 15 15 0
HSP90AB1-203 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 2 intact, hippie 70 255 29 29 0
HSPA4L-201 HSPA4L O95757 Heat shock 70 kDa protein 4L chr4 Not Cancer Driver No 1 hippie, biogrid 57 268 19 19 0
HSPA8-224 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 82 252 28 28 0
KAT6A-201 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 Census, Compendium Yes 1 hippie 119 1424 67 67 0
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 76 95 12 12 1
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 50 223 18 18 1
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MFN2-201 MFN2 O95140 Mitofusin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 60 82 7 7 19
MTRF1L-203 MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 17 185 5 5 0
NEK8-201 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 intact, hippie 75 167 29 29 3
NOX5-201 NOX5 Q96PH1 NADPH oxidase 5 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 94 95 7 7 0
NPHP4-201 NPHP4 O75161 Nephrocystin-4 chr1 Not Cancer Driver No 1 intact, hippie 137 474 44 44 17
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie 272 10 0 0 12
NSMCE1-201 NSMCE1 Q8WV22 Non-structural maintenance of chromosomes element 1 homolog chr16 Not Cancer Driver No 1 biogrid 21 31 2 2 0
OGT-202 OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 111 90 9 9 2
PCID2-202 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 34 13 2 2 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PTGES3-201 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 8 52 2 2 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 105 612 54 54 1
RELCH-202 RELCH Q9P260 RAB11-binding protein RELCH chr18 Not Cancer Driver No 1 hippie 86 386 18 18 0
RET-202 RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 intact, biogrid 176 108 11 11 91
RXFP4-201 RXFP4 Q8TDU9 Relaxin-3 receptor 2 chr1 Not Cancer Driver No 1 intact, hippie 27 15 1 1 0
S100A9-201 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie, biogrid 16 76 8 8 0
SERPINB13-202 SERPINB13 Q9UIV8 Serpin B13 chr18 Not Cancer Driver No 2 intact, hippie, biogrid 55 55 9 9 0
SF3A3-201 SF3A3 Q12874 Splicing factor 3A subunit 3 chr1 Not Cancer Driver No 1 hippie, biogrid 51 182 16 16 0
SLC27A6-201 SLC27A6 Q9Y2P4 Long-chain fatty acid transport protein 6 chr5 Not Cancer Driver No 2 hippie, biogrid 134 2 1 1 0
SLK-202 SLK Q9H2G2 STE20-like serine/threonine-protein kinase chr10 Not Cancer Driver No 1 hippie 94 967 65 65 0
SNAPC1-201 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 Not Cancer Driver No 1 biogrid 24 159 11 11 0
SNAPC3-202 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 Not Cancer Driver No 1 intact, hippie 23 99 2 2 0
SRSF2-202 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 Census, Compendium Yes 1 hippie, biogrid 16 221 16 16 0
STK26-202 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 1 hippie, biogrid 44 119 14 14 0
TBK1-201 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 intact, hippie 68 42 4 4 12
TCOF1-207 TCOF1 Q13428 Treacle protein chr5 Not Cancer Driver No 1 intact, hippie 107 1462 109 109 1
TLN2-211 TLN2 Q9Y4G6 Talin-2 chr15 Not Cancer Driver No 1 hippie, biogrid 267 896 108 108 0
TMOD4-201 TMOD4 Q9NZQ9 Tropomodulin-4 chr1 Not Cancer Driver No 1 intact, hippie 24 219 13 13 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIM56-201 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 Not Cancer Driver No 1 hippie 79 221 31 31 0
TRIP13-201 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 49 30 5 5 1
TRMT6-201 TRMT6 Q9UJA5 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 chr20 Not Cancer Driver No 1 hippie, biogrid 32 209 12 12 0
TSN-201 TSN Q15631 Translin chr2 Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 0
TTC4-201 TTC4 O95801 Tetratricopeptide repeat protein 4 chr1 Not Cancer Driver No 1 biogrid 36 101 10 10 0
TUBA1A-202 TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 45 52 6 6 6
TUBA4A-201 TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie, biogrid 50 39 2 2 4
TULP3-202 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 54 218 26 26 1
TXLNG-201 TXLNG Q9NUQ3 Gamma-taxilin chrX Not Cancer Driver No 1 hippie, biogrid 33 376 25 25 0
UBE2S-201 UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 Not Cancer Driver No 1 hippie, biogrid 15 102 5 5 0
UBE4B-202 UBE4B O95155 Ubiquitin conjugation factor E4 B chr1 Not Cancer Driver No 1 hippie, biogrid 119 435 38 38 0
UPF1-207 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 hippie, biogrid 114 330 33 33 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12
VPS26A-201 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 2 hippie, biogrid 21 45 3 3 0
VPS29-206 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 2 hippie, biogrid 15 0 0 0 0
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 2 hippie, biogrid 55 99 7 7 1
VPS36-201 VPS36 Q86VN1 Vacuolar protein-sorting-associated protein 36 chr13 Not Cancer Driver No 1 hippie, biogrid 27 94 9 9 0
WWOX-214 WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 50 109 7 7 3