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TTF2-201 ,TTF2 ,Q9UNY4
  • Number of Interaction partner in intact: 48
  • Number of Interaction partner in biogrid: 61
  • Number of Interaction partner in hippie: 122
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAT1-201 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 29 32 1 1 10
ACTB-217 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 96 43 5 5 4
AKAP10-201 AKAP10 O43572 A-kinase anchor protein 10, mitochondrial chr17 Not Cancer Driver No 1 hippie 36 306 14 14 0
AMZ1-207 AMZ1 Q400G9 Archaemetzincin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 60 152 15 15 0
ASB13-201 ASB13 Q8WXK3 Ankyrin repeat and SOCS box protein 13 chr10 Not Cancer Driver No 1 hippie, biogrid 35 8 1 1 0
ATG7-226 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 Compendium Yes 1 hippie, biogrid 60 54 6 6 6
BAG2-201 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 13 112 7 7 0
BICD2-202 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 83 546 51 51 10
BRCA2-201 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 1 hippie 310 1545 152 152 46
BRD7-201 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 58 485 33 33 0
CCT8L2-201 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 196 104 41 41 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 60 621 46 46 0
CDKL3-201 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 Not Cancer Driver No 1 intact, hippie 43 278 25 25 0
CEP120-201 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 70 449 35 35 1
CEP128-209 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 139 902 117 117 0
CEP152-202 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 128 990 74 74 2
CEP162-202 CEP162 Q5TB80 Centrosomal protein of 162 kDa chr6 Not Cancer Driver No 1 intact, hippie 121 1061 97 97 0
CETN1-201 CETN1 Q12798 Centrin-1 chr18 Not Cancer Driver No 2 intact, hippie, biogrid 47 105 30 30 0
CETN2-201 CETN2 P41208 Centrin-2 chrX Not Cancer Driver No 1 intact, hippie 17 97 5 5 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CIB2-201 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 Not Cancer Driver No 1 hippie, biogrid 21 8 0 0 8
CIC-206 CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 216 1552 207 207 0
CLPB-201 CLPB Q9H078 Mitochondrial disaggregase chr11 Not Cancer Driver No 3 intact, hippie, biogrid 54 224 22 22 20
CNTRL-205 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 166 1560 115 115 0
CNTROB-202 CNTROB Q8N137 Centrobin chr17 Not Cancer Driver No 1 intact, hippie 72 843 71 71 0
COMMD1-201 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 17 17 0 0 0
CREB1-201 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 intact, hippie 14 278 13 13 0
CRYBB3-201 CRYBB3 P26998 Beta-crystallin B3 chr22 Not Cancer Driver No 1 hippie, biogrid 21 35 3 3 2
D2HGDH-201 D2HGDH Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 42 47 1 1 0
DCP1A-206 DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 Not Cancer Driver No 1 intact, hippie 38 385 27 27 0
DCTN1-226 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 2 intact, hippie, biogrid 129 818 84 84 9
DKK3-217 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 35 162 14 14 0
DNAI2-201 DNAI2 Q9GZS0 Dynein axonemal intermediate chain 2 chr17 Not Cancer Driver No 1 hippie, biogrid 100 210 32 32 0
DNAJA2-201 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie, biogrid 34 174 18 18 0
DR1-202 DR1 Q01658 Protein Dr1 chr1 Not Cancer Driver No 1 hippie 18 85 11 11 0
DRAP1-201 DRAP1 Q14919 Dr1-associated corepressor chr11 Not Cancer Driver No 1 hippie 10 170 4 4 0
EEF1AKMT3-201 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 16 34 1 1 0
EMD-202 EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 29 160 18 18 3
EMILIN1-201 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 hippie, biogrid 89 671 50 50 1
ENST00000647725 FOXP1 Q9H334 Forkhead box protein P1 chr3 Census, Compendium Yes 1 intact, hippie 83 449 54 54 3
ENTR1-202 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 Not Cancer Driver No 1 hippie 43 270 30 30 0
FAM131B-202 FAM131B Q86XD5 Protein FAM131B chr7 Census Yes 1 intact, hippie, biogrid 65 276 48 48 0
FKBP8-206 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 50 161 19 19 0
FLT3-201 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 Census, Compendium Yes 1 biogrid 153 64 19 19 0
FLT4-201 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 biogrid 203 259 33 33 14
FOXL2-201 FOXL2 P58012 Forkhead box protein L2 chr3 Census, Compendium Yes 1 intact, hippie 33 258 16 16 22
FOXN1-203 FOXN1 O15353 Forkhead box protein N1 chr17 Not Cancer Driver No 1 intact, hippie 83 485 62 62 2
FOXP1-254 FOXP1 Q9H334 Forkhead box protein P1 chr3 Census, Compendium Yes 1 intact, hippie 83 449 54 54 3
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 64 184 24 24 2
GMEB2-203 GMEB2 Q9UKD1 Glucocorticoid modulatory element-binding protein 2 chr20 Not Cancer Driver No 1 hippie 70 277 34 34 0
GOLGA1-202 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 68 585 51 51 0
GRHL1-201 GRHL1 Q9NZI5 Grainyhead-like protein 1 homolog chr2 Not Cancer Driver No 1 intact 72 261 29 29 0
HAVCR2-201 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 45 17 1 1 3
HDAC11-201 HDAC11 Q96DB2 Histone deacetylase 11 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 44 18 7 7 0
HDAC7-209 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 70 571 43 43 0
HINFP-201 HINFP Q9BQA5 Histone H4 transcription factor chr11 Not Cancer Driver No 1 hippie 49 156 20 20 0
HNRNPA1-202 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 intact, hippie 33 290 22 22 4
HNRNPA2B1-201 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 Census, Compendium Yes 1 intact, hippie 35 255 13 13 1
IL17RA-201 IL17RA Q96F46 Interleukin-17 receptor A chr22 Not Cancer Driver No 1 intact, hippie, biogrid 70 304 14 14 0
IMPDH2-201 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 52 6 1 1 0
IQCF1-201 IQCF1 Q8N6M8 IQ domain-containing protein F1 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 31 70 12 12 0
JUN-201 JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 26 283 17 17 0
KDF1-201 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie 43 279 35 35 0
KIF4A-201 KIF4A O95239 Chromosome-associated kinesin KIF4A chrX Not Cancer Driver No 1 intact, hippie 144 677 89 89 0
KLHL34-201 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 hippie, biogrid 79 77 12 12 0
KLK1-201 KLK1 P06870 Kallikrein-1 chr19 Not Cancer Driver No 1 hippie, biogrid 39 22 2 2 0
LAMTOR5-206 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 Not Cancer Driver No 1 hippie, biogrid 8 17 0 0 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
MAP2K2-201 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 Census Yes 1 hippie, biogrid 45 107 13 13 3
MAPRE3-201 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 24 120 11 11 0
MATR3-201 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 81 613 61 61 3
MRFAP1L1-201 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 8 59 4 4 0
MYB-205 MYB P10242 Transcriptional activator Myb chr6 Census Yes 1 hippie 69 528 57 57 0
MYBL2-201 MYBL2 P10244 Myb-related protein B chr20 Not Cancer Driver No 1 hippie 74 511 53 53 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NAA40-202 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 16 31 1 1 0
NFKB1-205 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 intact, hippie 62 345 30 30 0
NIN-202 NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 177 1402 121 121 2
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 intact, hippie 193 891 140 140 0
NRBP1-203 NRBP1 Q9UHY1 Nuclear receptor-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 44 190 19 19 0
NUBP2-201 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 Not Cancer Driver No 1 hippie, biogrid 28 14 1 1 0
NVL-201 NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 1 intact, hippie 78 270 26 26 0
OC90-201 OC90 Q02509 Otoconin-90 chr8 Not Cancer Driver No 1 hippie, biogrid 98 122 28 28 0
PCM1-201 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 1 intact, hippie 104 1673 94 94 0
PDCD6IP-201 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 Not Cancer Driver No 1 intact, hippie 58 275 17 17 0
PEX19-201 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 26 267 23 23 0
PFN1-201 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 13 7 1 1 3
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PPARD-203 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 Not Cancer Driver No 1 hippie, biogrid 51 70 5 5 0
PPM1M-202 PPM1M Q96MI6 Protein phosphatase 1M chr3 Not Cancer Driver No 1 hippie, biogrid 14 87 1 1 0
PPP6R1-201 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 60 473 36 36 0
PRDX4-202 PRDX4 Q13162 Peroxiredoxin-4 chrX Not Cancer Driver No 1 intact, hippie 31 29 2 2 0
PSMC4-201 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 Not Cancer Driver No 2 intact, hippie, biogrid 38 21 2 2 0
PTGES3-201 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 8 52 2 2 0
PUDP-201 PUDP Q08623 Pseudouridine-5'-phosphatase chrX Not Cancer Driver No 1 hippie 32 9 0 0 0
PYHIN1-203 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 139 293 81 81 0
RAB2B-201 RAB2B Q8WUD1 Ras-related protein Rab-2B chr14 Not Cancer Driver No 1 intact, hippie, biogrid 17 48 2 2 0
RABL2A-203 RABL2A Q9UBK7 Rab-like protein 2A chr2 Not Cancer Driver No 1 hippie, biogrid 13 44 3 3 0
RFXANK-201 RFXANK O14593 DNA-binding protein RFXANK chr19 Not Cancer Driver No 1 hippie, biogrid 13 122 4 4 1
RPGR-201 RPGR Q92834 X-linked retinitis pigmentosa GTPase regulator chrX Not Cancer Driver No 1 intact, hippie 59 643 29 29 20
S100B-201 S100B P04271 Protein S100-B chr21 Not Cancer Driver No 1 hippie, biogrid 8 14 0 0 0
SIRT3-201 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 25 60 2 2 0
SKAP1-201 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 58 132 24 24 0
SKIL-201 SKIL P12757 Ski-like protein chr3 Not Cancer Driver No 1 intact, hippie 55 359 24 24 0
SMAD1-201 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 Not Cancer Driver No 1 hippie 39 162 19 19 0
SMAD7-201 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 Not Cancer Driver No 1 intact, hippie 38 140 0 0 0
SOHLH1-201 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 36 255 29 29 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 41 271 24 24 30
SRF-201 SRF P11831 Serum response factor chr6 Not Cancer Driver No 1 intact, hippie 30 443 29 29 0
SULT1C4-201 SULT1C4 O75897 Sulfotransferase 1C4 chr2 Not Cancer Driver No 1 hippie, biogrid 39 22 4 4 0
TACC3-201 TACC3 Q9Y6A5 Transforming acidic coiled-coil-containing protein 3 chr4 Not Cancer Driver No 1 hippie 76 719 67 67 0
TCF12-201 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 1 intact, hippie 65 683 65 65 3
TCF4-202 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 105 662 104 104 10
TFAP4-201 TFAP4 Q01664 Transcription factor AP-4 chr16 Compendium Yes 1 hippie 49 287 41 41 0
THTPA-201 THTPA Q9BU02 Thiamine-triphosphatase chr14 Not Cancer Driver No 1 hippie, biogrid 18 56 4 4 0
TJP2-202 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 916 80 80 1
TNIP1-211 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 2 intact, hippie 62 628 60 60 0
TOP3A-201 TOP3A Q13472 DNA topoisomerase 3-alpha chr17 Not Cancer Driver No 1 hippie, biogrid 79 293 28 28 2
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TUBB-205 TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie, biogrid 29 63 5 5 5
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
UBXN6-201 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 50 135 21 21 0
VIM-209 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 67 316 45 45 1
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
XPO1-201 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 84 33 5 5 0
ZNG1A-202 ZNG1A Q9BRT8 Zinc-regulated GTPase metalloprotein activator 1A chr9 Not Cancer Driver No 1 intact 20 59 4 4 0
ZSCAN1-201 ZSCAN1 Q8NBB4 Zinc finger and SCAN domain-containing protein 1 chr19 Not Cancer Driver No 1 intact, hippie 105 299 76 76 0