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TXNDC12-201 ,TXNDC12 ,O95881
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 106
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2-201 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 45 28 5 5 0
ABHD10-201 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 29 7 2 2 0
ABHD11-201 ABHD11 Q8NFV4 Protein ABHD11 chr7 Not Cancer Driver No 1 hippie, biogrid 33 72 5 5 0
ACADSB-201 ACADSB P45954 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 39 16 2 2 1
ACADVL-203 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 30 101 2 2 34
AK2-214 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 17 76 8 8 2
AK3-202 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 20 33 2 2 0
AK4-201 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 16 24 2 2 0
ARHGEF1-203 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 100 457 54 54 0
BRAF-220 BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 intact, hippie 755 311 30 30 35
C1orf198-201 C1orf198 Q9H425 Uncharacterized protein C1orf198 chr1 Not Cancer Driver No 1 hippie, biogrid 31 305 27 27 0
CAMLG-201 CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 Not Cancer Driver No 1 intact, hippie 23 158 13 13 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 intact, hippie 23 2 0 0 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 21 23 1 1 1
COA4-201 COA4 Q9NYJ1 Cytochrome c oxidase assembly factor 4 homolog, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 85 10 10 0
COMT-202 COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 hippie, biogrid 16 5 0 0 0
COX17-201 COX17 Q14061 Cytochrome c oxidase copper chaperone chr3 Not Cancer Driver No 1 hippie, biogrid 5 16 1 1 0
CTSB-202 CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 2 hippie, biogrid 36 7 2 2 0
CTSL-203 CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 36 34 5 5 0
CTSS-201 CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
CYB5R3-201 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 8
CYP51A1-201 CYP51A1 Q16850 Lanosterol 14-alpha demethylase chr7 Not Cancer Driver No 1 hippie, biogrid 31 7 0 0 0
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 26 181 19 19 0
DIAPH2-201 DIAPH2 O60879 Protein diaphanous homolog 2 chrX Not Cancer Driver No 1 hippie, biogrid 67 460 23 23 0
DPF2-205 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 intact, hippie 49 179 21 21 5
EFTUD2-202 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 100 179 22 22 3
ENO1-201 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie, biogrid 37 21 2 2 0
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 21 23 1 1 1
EPHA10-202 EPHA10 Q5JZY3 Ephrin type-A receptor 10 chr1 Not Cancer Driver No 1 intact, biogrid 129 226 36 36 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 92 198 19 19 2
FBP1-201 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 24 19 0 0 4
FKBP4-201 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie, biogrid 39 134 11 11 0
FKBP7-204 FKBP7 Q9Y680 Peptidyl-prolyl cis-trans isomerase FKBP7 chr2 Not Cancer Driver No 1 intact, hippie 19 52 8 8 0
FXN-203 FXN Q16595 Frataxin, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 17 75 1 1 8
GABARAPL2-201 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie, biogrid 4 2 1 1 0
GABRQ-201 GABRQ Q9UN88 Gamma-aminobutyric acid receptor subunit theta chrX Not Cancer Driver No 1 intact, hippie 124 175 44 44 0
GIMAP8-201 GIMAP8 Q8ND71 GTPase IMAP family member 8 chr7 Not Cancer Driver No 1 hippie, biogrid 152 139 21 21 0
GLRX5-201 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 5 23 0 0 2
GOT2-201 GOT2 P00505 Aspartate aminotransferase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 45 25 3 3 1
GUK1-209 GUK1 Q16774 Guanylate kinase chr1 Not Cancer Driver No 1 hippie, biogrid 17 73 6 6 0
H2AX-202 H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 1 intact 19 68 8 8 0
HADH-201 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 24 22 4 4 3
HCCS-202 HCCS P53701 Holocytochrome c-type synthase chrX Not Cancer Driver No 1 hippie, biogrid 46 117 24 24 1
HCK-202 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 intact, hippie 89 124 22 22 0
HINT1-201 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 1 hippie, biogrid 7 6 0 0 7
HMGCL-203 HMGCL P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 16 8 2 2 17
IQGAP2-201 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 Not Cancer Driver No 1 hippie, biogrid 159 257 36 36 0
KIF23-201 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 74 561 45 45 1
KLHL2-201 KLHL2 O95198 Kelch-like protein 2 chr4 Not Cancer Driver No 1 hippie 54 43 2 2 0
LAMTOR2-203 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 Not Cancer Driver No 1 hippie, biogrid 9 0 0 0 0
LYPLA1-201 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 14 12 0 0 0
MCF2L2-201 MCF2L2 Q86YR7 Probable guanine nucleotide exchange factor MCF2L2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 155 309 46 46 0
MPST-201 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 18 72 9 9 0
MSRB2-201 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 11 66 6 6 0
MSRB3-202 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 Not Cancer Driver No 1 hippie, biogrid 32 42 12 12 1
MTHFD2-201 MTHFD2 P13995 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 26 39 4 4 0
MTPN-201 MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 7 11 3 3 0
MX2-201 MX2 P20592 Interferon-induced GTP-binding protein Mx2 chr21 Not Cancer Driver No 1 hippie, biogrid 71 160 19 19 0
MZT2A-201 MZT2A Q6P582 Mitotic-spindle organizing protein 2A chr2 Not Cancer Driver No 2 hippie, biogrid 11 116 10 10 0
MZT2B-201 MZT2B Q6NZ67 Mitotic-spindle organizing protein 2B chr2 Not Cancer Driver No 2 intact, hippie, biogrid 9 113 9 9 0
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 9 36 4 4 0
NENF-201 NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 12 98 6 6 0
NME7-201 NME7 Q9Y5B8 Nucleoside diphosphate kinase 7 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 40 0 0 0 0
NOS2-201 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie, biogrid 147 201 26 26 0
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 25 249 19 19 0
PEBP1-201 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 17 77 11 11 0
PIH1D1-201 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 24 160 13 13 0
PKM-202 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 53 58 11 11 0
PMPCA-201 PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 48 23 3 3 4
PPA2-201 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 25 71 3 3 9
PRDX5-201 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
PRKD1-201 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 164 190 31 31 2
PRNP-201 PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 28 117 8 8 19
PSAP-201 PSAP P07602 Prosaposin chr10 Not Cancer Driver No 1 hippie, biogrid 46 28 2 2 7
PTPRO-201 PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 155 137 28 28 0
RAB11FIP5-201 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 52 533 44 44 0
RAB1A-203 RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 9 38 2 2 0
RAB7A-201 RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie, biogrid 19 11 0 0 4
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
SBF2-201 SBF2 Q86WG5 Myotubularin-related protein 13 chr11 Not Cancer Driver No 1 hippie 140 367 37 37 0
SGTA-201 SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 Not Cancer Driver No 1 intact, hippie 27 164 18 18 0
SGTB-201 SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 19 114 8 8 0
SH2D3C-201 SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 intact, hippie 81 443 52 52 0
SRI-201 SRI P30626 Sorcin chr7 Not Cancer Driver No 1 hippie, biogrid 8 32 0 0 0
SUMF2-208 SUMF2 Q8NBJ7 Inactive C-alpha-formylglycine-generating enzyme 2 chr7 Not Cancer Driver No 1 hippie, biogrid 23 105 8 8 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TBCA-202 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie, biogrid 7 30 2 2 0
TLN1-201 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 211 1110 90 90 0
TM2D3-201 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 Not Cancer Driver No 2 hippie, biogrid 26 13 3 3 0
TMEM106B-202 TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 22 57 4 4 1
TNIP2-201 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 28 318 21 21 0
TRIAP1-202 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 Not Cancer Driver No 1 hippie, biogrid 8 20 1 1 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TUBG1-201 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 2 intact, hippie, biogrid 42 44 9 9 3
TUBGCP2-201 TUBGCP2 Q9BSJ2 Gamma-tubulin complex component 2 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 91 94 11 11 0
TUBGCP3-201 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 2 hippie, biogrid 70 157 12 12 0
TUBGCP4-201 TUBGCP4 Q9UGJ1 Gamma-tubulin complex component 4 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 48 62 4 4 0
TUBGCP5-205 TUBGCP5 Q96RT8 Gamma-tubulin complex component 5 chr15 Not Cancer Driver No 2 hippie, biogrid 83 159 8 8 0
TUBGCP6-201 TUBGCP6 Q96RT7 Gamma-tubulin complex component 6 chr22 Not Cancer Driver No 2 hippie, biogrid 171 818 80 80 0
TXLNA-202 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 hippie, biogrid 55 481 46 46 0
TXN-202 TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie, biogrid 5 0 0 0 0
TXNRD2-204 TXNRD2 Q9NNW7 Thioredoxin reductase 2, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 51 47 4 4 0
UBQLN1-202 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 40 545 38 38 0
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 intact, hippie 64 581 61 61 8
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 77 141 19 19 0
VBP1-201 VBP1 P61758 Prefoldin subunit 3 chrX Not Cancer Driver No 1 hippie, biogrid 16 47 5 5 0
YTHDC1-201 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 intact, hippie 52 597 36 36 0
ZDHHC17-201 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 61 50 6 6 0