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UBE4B-202 ,UBE4B ,O95155
  • Number of Interaction partner in intact: 11
  • Number of Interaction partner in biogrid: 53
  • Number of Interaction partner in hippie: 111
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AHCYL1-202 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 41 109 11 11 0
AMZ1-207 AMZ1 Q400G9 Archaemetzincin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 60 152 15 15 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
ATP6V1F-201 ATP6V1F Q16864 V-type proton ATPase subunit F chr7 Not Cancer Driver No 1 hippie, biogrid 8 12 1 1 0
ATXN3-251 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 intact, hippie 25 183 12 12 0
BTRC-202 BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 57 45 3 3 0
CASP3-201 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 19 64 1 1 0
CASP6-201 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 19 24 4 4 0
CASP7-203 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 28 75 7 7 0
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 84 513 44 44 4
CDC25A-201 CDC25A P30304 M-phase inducer phosphatase 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 45 314 27 27 0
CDC27-201 CDC27 P30260 Cell division cycle protein 27 homolog chr17 Not Cancer Driver No 1 hippie 70 289 26 26 0
CDKN2A-201 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 1 intact, hippie 151 83 81 81 30
CNTN2-201 CNTN2 Q02246 Contactin-2 chr1 Not Cancer Driver No 1 hippie 130 371 56 56 0
CTDP1-208 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 Not Cancer Driver No 1 intact, hippie 96 627 68 68 0
DNAJC7-203 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie 26 102 8 8 0
DUSP16-202 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 55 273 26 26 0
EDEM1-201 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 44 141 5 5 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ENST00000598884 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie, biogrid 14 104 10 10 0
ENST00000661438 NUSAP1 Q9BXS6 Nucleolar and spindle-associated protein 1 chr15 Not Cancer Driver No 1 hippie 34 420 30 30 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 92 198 19 19 2
EYA3-203 EYA3 Q99504 Eyes absent homolog 3 chr1 Not Cancer Driver No 1 hippie, biogrid 44 310 30 30 0
FBXW11-201 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 41 20 2 2 6
FEZ1-201 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 Not Cancer Driver No 1 hippie 47 278 37 37 0
FOXK1-201 FOXK1 P85037 Forkhead box protein K1 chr7 Not Cancer Driver No 1 hippie, biogrid 68 514 46 46 0
GZMB-201 GZMB P10144 Granzyme B chr14 Not Cancer Driver No 1 hippie 31 103 13 13 0
HDLBP-201 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie, biogrid 143 555 61 61 0
HGS-201 HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 83 535 62 62 0
HNRNPL-201 HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 61 283 23 23 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 129 16 2 2 10
IGBP1-202 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 32 194 18 18 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LRRC73-201 LRRC73 Q5JTD7 Leucine-rich repeat-containing protein 73 chr6 Not Cancer Driver No 1 hippie, biogrid 29 92 14 14 0
MAPK3-201 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 32 49 3 3 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
MRPL53-201 MRPL53 Q96EL3 Large ribosomal subunit protein mL53 chr2 Not Cancer Driver No 1 hippie, biogrid 19 22 1 1 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NDUFA2-201 NDUFA2 O43678 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 chr5 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 0
NDUFA7-201 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie, biogrid 14 104 10 10 0
NLRP10-202 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 Not Cancer Driver No 1 hippie, biogrid 156 96 24 24 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 133 57 8 8 23
NUDCD3-202 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 hippie 22 199 12 12 0
NUSAP1-208 NUSAP1 Q9BXS6 Nucleolar and spindle-associated protein 1 chr15 Not Cancer Driver No 1 hippie 34 416 30 30 0
OR7A5-201 OR7A5 Q15622 Olfactory receptor 7A5 chr19 Not Cancer Driver No 1 hippie, biogrid 52 1 0 0 0
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 25 34 3 3 0
PCDHA8-202 PCDHA8 Q9Y5H6 Protocadherin alpha-8 chr5 Not Cancer Driver No 1 hippie, biogrid 260 274 55 55 0
PCID2-202 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 34 13 2 2 0
PDE3A-201 PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A chr12 Not Cancer Driver No 1 hippie 215 530 95 95 3
PGAM5-203 PGAM5 Q96HS1 Serine/threonine-protein phosphatase PGAM5, mitochondrial chr12 Not Cancer Driver No 1 hippie 23 103 7 7 0
PGRMC1-201 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 23 74 11 11 0
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 46 99 8 8 24
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PPIF-201 PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 13 44 2 2 0
PPP3CA-203 PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 Compendium Yes 1 hippie 63 140 24 24 7
PRC1-202 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 44 236 17 17 0
PRMT1-202 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 37 18 0 0 0
PSMB1-201 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 hippie, biogrid 20 15 2 2 0
RAD23A-203 RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie 41 284 34 34 0
RAD23B-201 RAD23B P54727 UV excision repair protein RAD23 homolog B chr9 Not Cancer Driver No 2 hippie, biogrid 29 326 24 24 0
RAF1-201 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 intact 64 169 30 30 18
RBM12-203 RBM12 Q9NTZ6 RNA-binding protein 12 chr20 Not Cancer Driver No 1 hippie 35 618 22 22 0
RIPK4-202 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact 99 232 31 31 3
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RPTOR-201 RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 149 242 18 18 0
SARNP-201 SARNP P82979 SAP domain-containing ribonucleoprotein chr12 Not Cancer Driver No 1 hippie, biogrid 21 195 21 21 0
SBDS-201 SBDS Q9Y3A5 Ribosome maturation protein SBDS chr7 Census Yes 1 hippie, biogrid 26 12 1 1 2
SCO2-202 SCO2 O43819 Protein SCO2 homolog, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 23 52 4 4 9
SF3B4-201 SF3B4 Q15427 Splicing factor 3B subunit 4 chr1 Not Cancer Driver No 1 hippie, biogrid 16 273 6 6 0
SMAD4-201 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 172 195 16 16 6
SRPRB-206 SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 1 hippie, biogrid 22 23 3 3 0
STAM-202 STAM Q92783 Signal transducing adapter molecule 1 chr10 Not Cancer Driver No 1 hippie 50 361 26 26 0
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie, biogrid 29 113 11 11 11
SULT1A1-201 SULT1A1 P50225 Sulfotransferase 1A1 chr16 Not Cancer Driver No 1 hippie, biogrid 52 15 2 2 0
THY1-201 THY1 P04216 Thy-1 membrane glycoprotein chr11 Not Cancer Driver No 1 hippie, biogrid 23 5 0 0 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
TP63-201 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 198 398 120 120 21
TP73-208 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 hippie 67 446 45 45 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 67 431 32 32 0
TRIP12-201 TRIP12 Q14669 E3 ubiquitin-protein ligase TRIP12 chr2 Not Cancer Driver No 1 hippie 154 847 82 82 4
TRIP6-201 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 hippie, biogrid 48 270 14 14 0
TTC4-201 TTC4 O95801 Tetratricopeptide repeat protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 36 101 10 10 0
TTC9C-202 TTC9C Q8N5M4 Tetratricopeptide repeat protein 9C chr11 Not Cancer Driver No 1 hippie, biogrid 13 81 3 3 0
TTK-202 TTK P33981 Dual specificity protein kinase TTK chr6 Not Cancer Driver No 1 hippie 106 354 40 40 0
UBA6-201 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 Not Cancer Driver No 1 hippie, biogrid 106 90 7 7 0
UBE2C-204 UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 Not Cancer Driver No 1 hippie, biogrid 13 40 0 0 0
UBE2D1-201 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 Not Cancer Driver No 1 hippie, biogrid 9 14 0 0 0
UBE2D2-201 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 Compendium Yes 1 hippie 14 13 1 1 0
UBE2D3-210 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 Not Cancer Driver No 1 intact, hippie 15 13 3 3 0
UBE2L3-201 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 Not Cancer Driver No 1 hippie, biogrid 13 32 3 3 0
UBE2V1-203 UBE2V1 Q13404 Ubiquitin-conjugating enzyme E2 variant 1 chr20 Not Cancer Driver No 1 biogrid 10 52 2 2 0
UBE4B-202 UBE4B O95155 Ubiquitin conjugation factor E4 B chr1 Not Cancer Driver No 1 hippie 119 435 38 38 0
UBL7-202 UBL7 Q96S82 Ubiquitin-like protein 7 chr15 Not Cancer Driver No 5 hippie, biogrid 25 192 18 18 0
UBQLN1-202 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 2 hippie, biogrid 40 545 38 38 0
UBXN1-202 UBXN1 Q04323 UBX domain-containing protein 1 chr11 Not Cancer Driver No 1 intact, hippie 30 271 29 29 0
UBXN7-201 UBXN7 O94888 UBX domain-containing protein 7 chr3 Not Cancer Driver No 1 hippie, biogrid 43 327 25 25 0
UCHL3-201 UCHL3 P15374 Ubiquitin carboxyl-terminal hydrolase isozyme L3 chr13 Not Cancer Driver No 1 hippie, biogrid 20 61 1 1 0
UFM1-201 UFM1 P61960 Ubiquitin-fold modifier 1 chr13 Not Cancer Driver No 1 hippie, biogrid 7 0 0 0 1
USP34-201 USP34 Q70CQ2 Ubiquitin carboxyl-terminal hydrolase 34 chr2 Not Cancer Driver No 1 hippie, biogrid 313 726 64 64 0
USP9X-202 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 1 hippie, biogrid 243 405 33 33 1
VAV2-201 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 Not Cancer Driver No 1 intact, hippie 85 136 15 15 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 5 intact, hippie, biogrid 74 186 14 14 12
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
VPS26A-201 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 hippie, biogrid 21 45 3 3 0
VPS29-206 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie, biogrid 55 99 7 7 1
VPS36-201 VPS36 Q86VN1 Vacuolar protein-sorting-associated protein 36 chr13 Not Cancer Driver No 1 hippie, biogrid 27 94 9 9 0
VPS4B-201 VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 Not Cancer Driver No 1 hippie, biogrid 33 195 14 14 0
XPC-201 XPC Q01831 DNA repair protein complementing XP-C cells chr3 Census, Compendium Yes 1 hippie 64 484 34 34 2
ZFYVE19-203 ZFYVE19 Q96K21 Abscission/NoCut checkpoint regulator chr15 Not Cancer Driver No 1 hippie, biogrid 32 365 20 20 1
ZPR1-201 ZPR1 O75312 Zinc finger protein ZPR1 chr11 Not Cancer Driver No 1 hippie, biogrid 22 291 16 16 0
ZRANB2-202 ZRANB2 O95218 Zinc finger Ran-binding domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 19 257 11 11 0