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UQCRH-201 ,UQCRH ,P07919
  • Number of Interaction partner in intact: 41
  • Number of Interaction partner in biogrid: 85
  • Number of Interaction partner in hippie: 123
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR10-201 ACTR10 Q9NZ32 Actin-related protein 10 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 35 29 2 2 0
ACTR1B-201 ACTR1B P42025 Beta-centractin chr2 Not Cancer Driver No 2 intact, hippie, biogrid 38 17 4 4 0
ADCK5-201 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 hippie 39 5 2 2 0
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 61 166 20 20 10
ALDOA-206 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 intact 36 65 7 7 3
APOE-201 APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 1 hippie, biogrid 20 124 5 5 10
ARL8A-201 ARL8A Q96BM9 ADP-ribosylation factor-like protein 8A chr1 Not Cancer Driver No 2 intact, hippie 22 0 0 0 0
ARMCX3-203 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 29 77 7 7 0
ASPH-203 ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 Not Cancer Driver No 1 hippie, biogrid 80 374 33 33 1
ATG16L1-203 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 54 240 19 19 1
ATP13A3-202 ATP13A3 Q9H7F0 Polyamine-transporting ATPase 13A3 chr3 Not Cancer Driver No 1 hippie, biogrid 110 49 6 6 1
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
ATP2A2-204 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 hippie, biogrid 106 78 13 13 40
ATP2A3-205 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 92 147 13 13 0
ATP5F1B-201 ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 85 7 7 1
ATP6V0D1-201 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
ATP6V1B2-201 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 hippie, biogrid 38 49 3 3 1
ATP6V1E1-201 ATP6V1E1 P36543 V-type proton ATPase subunit E 1 chr22 Not Cancer Driver No 1 hippie, biogrid 18 28 2 2 2
BCKDHA-201 BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 38 123 17 17 11
BORCS6-201 BORCS6 Q96GS4 BLOC-1-related complex subunit 6 chr17 Not Cancer Driver No 1 hippie 16 270 11 11 0
CANX-201 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie, biogrid 57 334 36 36 0
CHCHD4-202 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 Not Cancer Driver No 1 hippie, biogrid 11 83 3 3 0
COQ10B-201 COQ10B Q9H8M1 Coenzyme Q-binding protein COQ10 homolog B, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 13 10 1 1 0
COQ2-206 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 hippie 16 25 0 0 17
COQ5-201 COQ5 Q5HYK3 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 41 15 2 2 0
COQ8B-202 COQ8B Q96D53 Atypical kinase COQ8B, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 52 117 13 13 8
CORO1C-201 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie, biogrid 41 84 12 12 0
COX4I1-201 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 13 5 1 1 1
COX7A2L-201 COX7A2L O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 11 0 0 0 0
CRELD1-206 CRELD1 Q96HD1 Protein disulfide isomerase CRELD1 chr3 Not Cancer Driver No 1 hippie, biogrid 28 44 6 6 4
CYB5B-201 CYB5B O43169 Cytochrome b5 type B chr16 Not Cancer Driver No 1 hippie, biogrid 16 59 2 2 0
CYC1-201 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 7 intact, hippie, biogrid 44 35 2 2 2
DCTN2-209 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 34 254 23 23 0
DCTN3-201 DCTN3 O75935 Dynactin subunit 3 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 14 3 0 0 0
DCTN4-203 DCTN4 Q9UJW0 Dynactin subunit 4 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 37 138 14 14 0
DCTN5-201 DCTN5 Q9BTE1 Dynactin subunit 5 chr16 Not Cancer Driver No 2 hippie, biogrid 19 0 0 0 0
DCTN6-201 DCTN6 O00399 Dynactin subunit 6 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 17 45 0 0 0
DOCK11-201 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX Not Cancer Driver No 2 hippie, biogrid 222 240 22 22 0
EEF1A1-201 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie, biogrid 98 100 10 10 0
EEF1B2-203 EEF1B2 P24534 Elongation factor 1-beta chr2 Not Cancer Driver No 1 hippie, biogrid 22 71 7 7 0
EEF2-201 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 86 79 9 9 1
EGLN3-201 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 21 13 0 0 0
EMC2-201 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie, biogrid 38 29 2 2 0
EMC4-202 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie, biogrid 8 17 1 1 0
EMC8-201 EMC8 O43402 ER membrane protein complex subunit 8 chr16 Not Cancer Driver No 1 hippie, biogrid 13 21 0 0 0
ENTREP3-202 ENTREP3 P81408 Protein ENTREP3 chr1 Not Cancer Driver No 1 intact 46 302 17 17 0
ERBB3-201 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie, biogrid 265 398 59 59 3
FAM131B-202 FAM131B Q86XD5 Protein FAM131B chr7 Census Yes 1 intact, hippie, biogrid 65 276 48 48 0
FMC1-201 FMC1 Q96HJ9 Protein FMC1 homolog chr7 Not Cancer Driver No 1 intact, hippie 8 30 1 1 0
FUCA2-201 FUCA2 Q9BTY2 Plasma alpha-L-fucosidase chr6 Not Cancer Driver No 1 intact, hippie, biogrid 29 2 0 0 0
GSDME-214 GSDME O60443 Gasdermin-E chr7 Not Cancer Driver No 1 hippie 64 14 2 2 0
HCST-201 HCST Q9UBK5 Hematopoietic cell signal transducer chr19 Not Cancer Driver No 1 hippie, biogrid 5 12 0 0 0
HDAC10-201 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 53 122 11 11 0
HMOX2-208 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 17 74 5 5 0
HTT-201 HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 261 668 51 51 2
ILF3-218 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 57 676 39 39 0
INS-202 INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 7 5 1 1 19
ITFG1-201 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 50 18 3 3 0
KLRC2-202 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 Not Cancer Driver No 1 hippie, biogrid 38 45 11 11 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LONP1-201 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 75 178 16 16 10
LRPPRC-201 LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 99 18 0 0 1
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
MAPK6-201 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 52 166 13 13 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 39 298 24 24 0
MECOM-217 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 225 751 120 120 3
MPV17-203 MPV17 P39210 Protein Mpv17 chr2 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 15
MT-CYB-201 MT-CYB P00156 Cytochrome b chrM Not Cancer Driver No 1 intact 0 0 0 0 0
MTRES1-201 MTRES1 Q9P0P8 Mitochondrial transcription rescue factor 1 chr6 Not Cancer Driver No 1 intact 16 45 2 2 0
MYLK2-201 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 Not Cancer Driver No 1 intact, hippie 92 278 51 51 2
NDFIP1-201 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 Not Cancer Driver No 1 intact, hippie 17 45 3 3 0
NDFIP2-201 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 Not Cancer Driver No 1 intact, hippie 21 198 11 11 0
NDUFA12-201 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 Not Cancer Driver No 1 intact, hippie 14 31 5 5 0
NDUFA8-201 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 1 hippie, biogrid 20 33 1 1 2
NDUFS1-201 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 58 40 3 3 2
NDUFS3-201 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 22 26 2 2 2
NDUFS4-201 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 18 93 12 12 1
NDUFS5-202 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 11 31 3 3 0
NDUFS7-201 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 30 31 2 2 1
NDUFS8-201 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 22 37 3 3 3
NDUFV1-201 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 45 57 3 3 3
NDUFV2-201 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 30 70 10 10 0
NENF-201 NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 12 98 6 6 0
NINL-201 NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 193 891 140 140 0
NNT-202 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 96 47 5 5 11
NPM1-201 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact, hippie 25 249 19 19 0
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 25 34 3 3 0
P2RY6-208 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 40 10 2 2 0
P4HA1-204 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 Not Cancer Driver No 1 hippie, biogrid 47 54 3 3 0
PBXIP1-202 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 69 606 60 60 0
PDHA1-205 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 40 43 4 4 19
PDHB-201 PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 20 4 0 0 2
PEX19-201 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 26 267 23 23 0
PHB2-203 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 25 26 4 4 0
POR-218 POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie, biogrid 49 94 4 4 9
PROC-201 PROC P04070 Vitamin K-dependent protein C chr2 Not Cancer Driver No 1 intact, hippie, biogrid 44 41 9 9 35
PRRG1-201 PRRG1 O14668 Transmembrane gamma-carboxyglutamic acid protein 1 chrX Not Cancer Driver No 1 intact, hippie 29 88 14 14 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 20 67 9 9 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 intact, hippie 61 2 0 0 6
RCN2-203 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie, biogrid 27 125 7 7 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RNF24-202 RNF24 Q9Y225 RING finger protein 24 chr20 Not Cancer Driver No 1 intact, hippie 11 13 2 2 0
RPL4-201 RPL4 P36578 Large ribosomal subunit protein uL4 chr15 Not Cancer Driver No 1 hippie, biogrid 31 222 15 15 0
SCYL3-203 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 Not Cancer Driver No 1 hippie, biogrid 56 250 18 18 0
SDHAF4-201 SDHAF4 Q5VUM1 Succinate dehydrogenase assembly factor 4, mitochondrial chr6 Not Cancer Driver No 1 hippie 12 78 9 9 0
SERPINB1-201 SERPINB1 P30740 Leukocyte elastase inhibitor chr6 Not Cancer Driver No 1 intact, hippie, biogrid 27 14 0 0 0
SFXN1-201 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 21 29 0 0 0
SHLD3-201 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 Not Cancer Driver No 1 intact 2 82 1 1 0
SIRT3-201 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 25 60 2 2 0
SLC11A2-229 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 47 39 4 4 3
SLC15A2-205 SLC15A2 Q16348 Solute carrier family 15 member 2 chr3 Not Cancer Driver No 1 hippie, biogrid 116 37 7 7 0
SLC2A9-201 SLC2A9 Q9NRM0 Solute carrier family 2, facilitated glucose transporter member 9 chr4 Not Cancer Driver No 1 hippie, biogrid 68 49 2 2 6
SLC39A4-202 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 58 116 9 9 9
SMC5-201 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 Not Cancer Driver No 1 intact 94 381 35 35 1
SPPL2B-209 SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 0 101 0 0 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 41 271 24 24 30
SSC5D-201 SSC5D A1L4H1 Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D chr19 Not Cancer Driver No 1 hippie, biogrid 40 1205 34 34 0
TMED2-201 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 16 25 2 2 0
TSPAN10-203 TSPAN10 Q9H1Z9 Tetraspanin-10 chr17 Not Cancer Driver No 1 hippie, biogrid 22 81 5 5 0
TUBB-205 TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 2 intact, hippie, biogrid 29 63 5 5 5
TUBGCP3-201 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie, biogrid 70 157 12 12 0
UQCR10-201 UQCR10 Q9UDW1 Cytochrome b-c1 complex subunit 9 chr22 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 0
UQCRB-201 UQCRB P14927 Cytochrome b-c1 complex subunit 7 chr8 Not Cancer Driver No 3 hippie, biogrid 8 2 0 0 0
UQCRC1-201 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 3 hippie, biogrid 41 55 3 3 2
UQCRC2-201 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 3 hippie, biogrid 31 48 5 5 1
UQCRFS1-201 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 27 47 1 1 1
UQCRQ-203 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 2 hippie, biogrid 8 12 1 1 1
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie, biogrid 74 186 14 14 12