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USP33-203 ,USP33 ,Q8TEY7
  • Number of Interaction partner in intact: 10
  • Number of Interaction partner in biogrid: 75
  • Number of Interaction partner in hippie: 114
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADRB2-201 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 36 35 4 4 0
AKAP1-202 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 77 541 50 50 0
APBA2-213 APBA2 Q99767 Amyloid-beta A4 precursor protein-binding family A member 2 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 151 429 98 98 0
ARRB1-202 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 37 154 11 11 0
ARRB2-201 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 39 122 19 19 0
ASIC5-201 ASIC5 Q9NY37 Acid-sensing ion channel 5 chr4 Not Cancer Driver No 1 hippie, biogrid 87 12 4 4 0
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
AURKA-208 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 25 180 17 17 0
BCAP31-201 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 27 104 13 13 0
BECN1-213 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 36 190 15 15 0
BTRC-202 BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 57 45 3 3 0
CGRRF1-201 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 20 34 4 4 0
CHRM5-201 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 Not Cancer Driver No 1 hippie 51 157 15 15 0
CKAP4-201 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 44 412 36 36 0
CRAMP1-202 CRAMP1 Q96RY5 Protein cramped-like chr16 Not Cancer Driver No 1 hippie 95 999 76 76 0
CT55-201 CT55 Q8WUE5 Cancer/testis antigen 55 chrX Not Cancer Driver No 1 hippie, biogrid 30 40 2 2 0
CTAG2-201 CTAG2 O75638 Cancer/testis antigen 2 chrX Not Cancer Driver No 1 hippie, biogrid 37 201 38 38 0
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 363 288 291 291 11
DDX56-201 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 Not Cancer Driver No 1 hippie, biogrid 40 108 9 9 0
DERL1-201 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 17 12 0 0 0
DIO2-201 DIO2 Q92813 Type II iodothyronine deiodinase chr14 Not Cancer Driver No 1 hippie 61 43 3 3 0
DISC1-209 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 106 520 65 65 0
DNAJC1-202 DNAJC1 Q96KC8 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 50 315 38 38 0
DUSP1-201 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 Not Cancer Driver No 1 hippie 26 7 0 0 0
EBAG9-201 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 27 175 25 25 0
EDEM1-201 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 44 141 5 5 0
EIF6-203 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 22 17 2 2 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
ELOB-203 ELOB Q15370 Elongin-B chr16 Not Cancer Driver No 1 hippie 5 69 3 3 0
ELOC-206 ELOC Q15369 Elongin-C chr8 Not Cancer Driver No 1 hippie 13 25 3 3 0
ELOVL5-201 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 33 25 2 2 2
EMD-202 EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 29 160 18 18 3
EXOC2-201 EXOC2 Q96KP1 Exocyst complex component 2 chr6 Not Cancer Driver No 1 hippie 74 134 10 10 0
GABRG2-215 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 Not Cancer Driver No 1 hippie, biogrid 155 2 0 0 11
GCGR-201 GCGR P47871 Glucagon receptor chr17 Not Cancer Driver No 1 hippie 12 56 2 2 4
GJD3-201 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 2 80 0 0 0
GNAI3-201 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie, biogrid 36 12 0 0 1
GPR17-202 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 Not Cancer Driver No 1 hippie, biogrid 40 16 3 3 0
GRIN2A-201 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 Census, Compendium Yes 1 hippie, biogrid 439 507 172 172 32
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 517 971 113 113 1
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 129 16 2 2 10
HSD17B11-201 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
HSD3B7-202 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 37 27 4 4 2
IFIT5-201 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 Not Cancer Driver No 1 hippie, biogrid 31 19 0 0 0
IL17RA-201 IL17RA Q96F46 Interleukin-17 receptor A chr22 Not Cancer Driver No 1 hippie, biogrid 70 304 14 14 0
IL32-223 IL32 P24001 Interleukin-32 chr16 Not Cancer Driver No 1 hippie, biogrid 19 70 8 8 0
ITGB3BP-201 ITGB3BP Q13352 Centromere protein R chr1 Not Cancer Driver No 1 hippie 15 123 12 12 0
KCNA2-201 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 76 83 12 12 6
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 771 7 2 2 22
KRR1-201 KRR1 Q13601 KRR1 small subunit processome component homolog chr12 Not Cancer Driver No 1 hippie, biogrid 28 194 17 17 0
KRT27-201 KRT27 Q7Z3Y8 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 1 hippie, biogrid 60 144 20 20 0
LDLRAD4-201 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 Not Cancer Driver No 1 hippie, biogrid 52 192 30 30 0
LMNA-205 LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie, biogrid 50 547 34 34 117
LPCAT4-201 LPCAT4 Q643R3 Lysophospholipid acyltransferase LPCAT4 chr15 Not Cancer Driver No 2 hippie, biogrid 38 92 7 7 0
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
LRRN2-203 LRRN2 O75325 Leucine-rich repeat neuronal protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 94 84 16 16 0
LRRTM1-201 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 151 57 16 16 0
MCOLN2-202 MCOLN2 Q8IZK6 Mucolipin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 65 0 0 0 0
MPPED1-203 MPPED1 O15442 Metallophosphoesterase domain-containing protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 55 26 9 9 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
NEURL4-202 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 hippie 145 753 83 83 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NUP155-201 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 128 221 17 17 1
OCIAD1-201 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 25 169 19 19 0
OTULINL-201 OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 34 21 0 0 0
PCGF6-202 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 2 hippie, biogrid 19 142 5 5 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 96 78 14 14 30
PRPF38B-203 PRPF38B Q5VTL8 Pre-mRNA-splicing factor 38B chr1 Not Cancer Driver No 1 hippie, biogrid 21 387 6 6 0
PXMP2-201 PXMP2 Q9NR77 Peroxisomal membrane protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 20 67 9 9 0
RAB7A-201 RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 19 11 0 0 4
RALA-201 RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 29 34 3 3 4
RALB-201 RALB P11234 Ras-related protein Ral-B chr2 Not Cancer Driver No 1 hippie 29 35 4 4 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
ROBO1-202 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 Not Cancer Driver No 1 hippie 245 1125 158 158 0
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 26 3 3 0
RXFP1-201 RXFP1 Q9HBX9 Relaxin receptor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 120 0 0 0 0
SAMM50-201 SAMM50 Q9Y512 Sorting and assembly machinery component 50 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 32 35 0 0 0
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 2 hippie, biogrid 6 60 5 5 0
SEC62-201 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 12 211 9 9 0
SELENBP1-201 SELENBP1 Q13228 Methanethiol oxidase chr1 Not Cancer Driver No 1 intact, hippie 52 31 3 3 2
SKP2-202 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 37 52 5 5 0
SLC25A46-201 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 28 98 2 2 4
SPA17-201 SPA17 Q15506 Sperm surface protein Sp17 chr11 Not Cancer Driver No 2 hippie, biogrid 13 137 12 12 0
SPINT2-201 SPINT2 O43291 Kunitz-type protease inhibitor 2 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 33 25 2 2 1
SPSB4-201 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 35 75 1 1 0
SSR1-201 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 17 115 5 5 0
ST7-201 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 37 64 6 6 0
STIM1-201 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 55 386 35 35 12
STN1-201 STN1 Q9H668 CST complex subunit STN1 chr10 Not Cancer Driver No 2 intact, hippie 34 27 3 3 2
STX4-201 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 39 153 16 16 0
TGFA-201 TGFA P01135 Protransforming growth factor alpha chr2 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
TKTL2-201 TKTL2 Q9H0I9 Transketolase-like protein 2 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 154 71 14 14 0
TLR2-203 TLR2 O60603 Toll-like receptor 2 chr4 Not Cancer Driver No 2 hippie, biogrid 84 0 0 0 0
TMEM134-201 TMEM134 Q9H6X4 Transmembrane protein 134 chr11 Not Cancer Driver No 1 hippie, biogrid 7 72 0 0 0
TMPO-202 TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie, biogrid 50 414 32 32 0
TMX1-201 TMX1 Q9H3N1 Thioredoxin-related transmembrane protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 18 62 6 6 0
TPTE2-211 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 Not Cancer Driver No 1 hippie, biogrid 131 34 9 9 0
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 51 62 5 5 0
TRIM54-202 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 hippie 47 98 11 11 0
TRIM63-201 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie 26 71 6 6 0
TRPC3-202 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 Not Cancer Driver No 1 hippie, biogrid 160 137 16 16 1
USP15-201 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 Not Cancer Driver No 1 hippie 103 260 31 31 0
USP20-203 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 Not Cancer Driver No 1 hippie 87 296 30 30 0
USP21-203 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 Not Cancer Driver No 1 hippie 86 230 44 44 0
USP28-201 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 Not Cancer Driver No 1 hippie 106 311 18 18 0
VAPA-202 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 2 intact, hippie, biogrid 20 184 11 11 0
VAPB-204 VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 3 intact, hippie, biogrid 10 138 7 7 3
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 85 117 15 15 84
VSX2-201 VSX2 P58304 Visual system homeobox 2 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 34 270 18 18 4
ZDHHC12-201 ZDHHC12 Q96GR4 Palmitoyltransferase ZDHHC12 chr9 Not Cancer Driver No 1 hippie, biogrid 15 13 1 1 0
ZFR-201 ZFR Q96KR1 Zinc finger RNA-binding protein chr5 Not Cancer Driver No 1 hippie, biogrid 71 596 44 44 0
ZNRF4-201 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 85 100 19 19 0