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VAMP3-201 ,VAMP3 ,Q15836
  • Number of Interaction partner in intact: 3
  • Number of Interaction partner in biogrid: 143
  • Number of Interaction partner in hippie: 257
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAP1-201 ACAP1 Q15027 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 chr17 Not Cancer Driver No 1 hippie 82 267 34 34 0
AHNAK2-201 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 hippie 765 5691 757 757 0
AIG1-202 AIG1 Q9NVV5 Androgen-induced gene 1 protein chr6 Not Cancer Driver No 1 hippie 11 9 0 0 0
ANKFY1-201 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 70 186 20 20 0
ANLN-201 ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie, biogrid 101 771 75 75 2
APP-201 APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 94 419 52 52 12
AQP6-201 AQP6 Q13520 Aquaporin-6 chr12 Not Cancer Driver No 1 hippie 38 22 4 4 0
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 16 5 0 0 0
ARL13B-203 ARL13B Q3SXY8 ADP-ribosylation factor-like protein 13B chr3 Not Cancer Driver No 1 hippie 48 251 34 34 3
ASPH-203 ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 Not Cancer Driver No 1 hippie, biogrid 80 374 33 33 1
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
ATP4A-201 ATP4A P20648 Potassium-transporting ATPase alpha chain 1 chr19 Not Cancer Driver No 1 hippie 152 122 21 21 0
ATP6V1C2-201 ATP6V1C2 Q8NEY4 V-type proton ATPase subunit C 2 chr2 Not Cancer Driver No 1 hippie, biogrid 45 47 7 7 0
B3GAT1-201 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 59 93 24 24 0
BCAP31-201 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie 27 104 13 13 0
BCL2L13-201 BCL2L13 Q9BXK5 Bcl-2-like protein 13 chr22 Not Cancer Driver No 1 hippie 32 291 18 18 0
BET1-201 BET1 O15155 BET1 homolog chr7 Not Cancer Driver No 1 hippie 8 7 2 2 0
BIK-201 BIK Q13323 Bcl-2-interacting killer chr22 Not Cancer Driver No 1 hippie 10 21 3 3 0
BSCL2-207 BSCL2 Q96G97 Seipin chr11 Not Cancer Driver No 1 hippie 37 126 7 7 5
BSND-201 BSND Q8WZ55 Barttin chr1 Not Cancer Driver No 1 hippie 48 210 31 31 3
C11orf52-201 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 14 109 11 11 0
C8orf82-202 C8orf82 Q6P1X6 UPF0598 protein C8orf82 chr8 Not Cancer Driver No 1 hippie, biogrid 9 11 0 0 0
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
CCDC8-201 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 63 509 62 62 0
CD4-201 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 2 hippie, biogrid 50 56 7 7 0
CD53-201 CD53 P19397 Leukocyte surface antigen CD53 chr1 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 0
CD79A-201 CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 Census Yes 1 hippie 20 28 1 1 0
CD81-201 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 22 0 0 0 0
CDC42-208 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
CDH1-201 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 125 401 70 70 5
CENPA-202 CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 1 hippie, biogrid 12 50 1 1 0
CENPM-201 CENPM Q9NSP4 Centromere protein M chr22 Not Cancer Driver No 1 hippie, biogrid 7 1 0 0 0
CIAO2A-201 CIAO2A Q9H5X1 Cytosolic iron-sulfur assembly component 2A chr15 Not Cancer Driver No 1 hippie 20 28 3 3 0
CLDN7-201 CLDN7 O95471 Claudin-7 chr17 Not Cancer Driver No 1 hippie 8 2 0 0 0
CLEC14A-201 CLEC14A Q86T13 C-type lectin domain family 14 member A chr14 Not Cancer Driver No 1 hippie 115 183 48 48 0
COMT-202 COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 hippie 16 5 0 0 0
COX8A-201 COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CPLX1-201 CPLX1 O14810 Complexin-1 chr4 Not Cancer Driver No 2 hippie, biogrid 17 134 17 17 0
CRYAA-201 CRYAA P02489 Alpha-crystallin A chain chr21 Not Cancer Driver No 1 hippie, biogrid 0 42 0 0 6
CTBP1-201 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 hippie 30 123 8 8 1
CXADR-201 CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 40 99 15 15 0
DERL1-201 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 17 12 0 0 0
DIRAS3-202 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie, biogrid 27 21 2 2 0
DNAJC5-201 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie 19 46 5 5 1
DUSP22-201 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 Not Cancer Driver No 2 hippie, biogrid 76 0 0 0 0
EBAG9-201 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 27 175 25 25 0
EBP-205 EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 hippie 22 9 0 0 7
EIF1B-201 EIF1B O60739 Eukaryotic translation initiation factor 1b chr3 Not Cancer Driver No 1 hippie 10 6 0 0 0
EIF2B2-201 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 Not Cancer Driver No 2 hippie, biogrid 34 83 9 9 9
ELOVL4-201 ELOVL4 Q9GZR5 Elongation of very long chain fatty acids protein 4 chr6 Not Cancer Driver No 1 hippie 44 23 2 2 1
ELOVL5-201 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 33 25 2 2 2
EMP3-201 EMP3 P54852 Epithelial membrane protein 3 chr19 Not Cancer Driver No 1 hippie 14 0 0 0 0
ENPP6-201 ENPP6 Q6UWR7 Glycerophosphocholine cholinephosphodiesterase ENPP6 chr4 Not Cancer Driver No 2 hippie, biogrid 61 7 1 1 0
ENST00000498285 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 Not Cancer Driver No 1 hippie 3 60 1 1 3
ENST00000695856 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 21 23 1 1 1
EPB41-201 EPB41 P11171 Protein 4.1 chr1 Not Cancer Driver No 1 hippie 69 557 48 48 0
EPHB2-204 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 biogrid 149 120 11 11 7
ERGIC1-202 ERGIC1 Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 27 26 0 0 0
ERGIC3-202 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 Not Cancer Driver No 1 hippie 32 23 1 1 0
FAM174A-201 FAM174A Q8TBP5 Membrane protein FAM174A chr5 Not Cancer Driver No 1 hippie 22 140 17 17 0
FAM209A-201 FAM209A Q5JX71 Protein FAM209A chr20 Not Cancer Driver No 1 hippie 17 53 3 3 0
FAM210B-201 FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 Not Cancer Driver No 1 hippie 7 32 0 0 0
FAM24B-202 FAM24B Q8N5W8 Protein FAM24B chr10 Not Cancer Driver No 1 hippie, biogrid 3 0 0 0 0
FAM9C-202 FAM9C Q8IZT9 Protein FAM9C chrX Not Cancer Driver No 1 hippie, biogrid 19 158 17 17 0
FGFR4-201 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 biogrid 101 163 27 27 0
FIS1-201 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 Not Cancer Driver No 1 hippie, biogrid 9 6 0 0 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 62 111 20 20 43
GJD3-201 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 2 80 0 0 0
GOLPH3-201 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 28 72 0 0 0
GORAB-202 GORAB Q5T7V8 RAB6-interacting golgin chr1 Not Cancer Driver No 1 hippie 45 285 35 35 0
GPR183-201 GPR183 P32249 G-protein coupled receptor 183 chr13 Not Cancer Driver No 2 hippie, biogrid 35 25 3 3 0
GPRC5B-201 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 Not Cancer Driver No 1 hippie, biogrid 72 76 19 19 0
GPX8-203 GPX8 Q8TED1 Probable glutathione peroxidase 8 chr5 Not Cancer Driver No 1 hippie 12 4 1 1 0
GSX1-201 GSX1 Q9H4S2 GS homeobox 1 chr13 Not Cancer Driver No 1 hippie, biogrid 17 138 10 10 0
HOXC9-201 HOXC9 P31274 Homeobox protein Hox-C9 chr12 Not Cancer Driver No 1 hippie, biogrid 25 144 12 12 0
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie, biogrid 129 16 2 2 10
HSD17B11-201 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
HSD3B7-202 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 37 27 4 4 2
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 263 2091 107 107 20
ICE2-201 ICE2 Q659A1 Little elongation complex subunit 2 chr15 Not Cancer Driver No 1 hippie, biogrid 78 399 31 31 0
IFITM3-201 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 7 19 2 2 0
IKBKE-203 IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 90 76 10 10 0
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 5 301 4 4 21
IL32-223 IL32 P24001 Interleukin-32 chr16 Not Cancer Driver No 1 hippie, biogrid 19 70 8 8 0
IPPK-201 IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 Not Cancer Driver No 1 hippie, biogrid 32 43 0 0 0
JPH4-201 JPH4 Q96JJ6 Junctophilin-4 chr14 Not Cancer Driver No 1 hippie, biogrid 48 517 47 47 0
KAT5-203 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 hippie 45 174 16 16 3
KCNE3-201 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
KCNK5-201 KCNK5 O95279 Potassium channel subfamily K member 5 chr6 Not Cancer Driver No 1 hippie 73 207 30 30 0
KIFAP3-201 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 Not Cancer Driver No 2 hippie, biogrid 89 71 8 8 0
KIR2DL1-202 KIR2DL1 P43626 Killer cell immunoglobulin-like receptor 2DL1 chr19 Not Cancer Driver No 1 hippie, biogrid 92 125 39 39 0
KIR2DL4-205 KIR2DL4 Q99706 Killer cell immunoglobulin-like receptor 2DL4 chr19 Not Cancer Driver No 1 hippie, biogrid 0 0 0 0 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 hippie, biogrid 771 7 2 2 22
KRTCAP3-201 KRTCAP3 Q53RY4 Keratinocyte-associated protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 14 37 3 3 0
LAMP1-201 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 2 hippie, biogrid 36 94 8 8 0
LAMP2-201 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 29 55 4 4 1
LAMP3-201 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 57 223 34 34 0
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 10 96 6 6 0
LHFPL2-201 LHFPL2 Q6ZUX7 LHFPL tetraspan subfamily member 2 protein chr5 Not Cancer Driver No 1 hippie, biogrid 12 9 0 0 0
LHFPL5-201 LHFPL5 Q8TAF8 LHFPL tetraspan subfamily member 5 protein chr6 Not Cancer Driver No 1 hippie 42 1 0 0 4
LMAN1-201 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 50 223 18 18 1
LMNA-205 LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 50 547 34 34 117
LMO3-215 LMO3 Q8TAP4 LIM domain only protein 3 chr12 Not Cancer Driver No 1 hippie 21 1 0 0 0
LRRIQ1-202 LRRIQ1 Q96JM4 Leucine-rich repeat and IQ domain-containing protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 284 887 143 143 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 78 85 10 10 0
MALL-201 MALL Q13021 MAL-like protein chr2 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
MANSC1-202 MANSC1 Q9H8J5 MANSC domain-containing protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 38 209 14 14 0
MAP1LC3B-201 MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 4 17 0 0 0
MARCKS-201 MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 5 328 5 5 0
MCTS1-202 MCTS1 Q9ULC4 Malignant T-cell-amplified sequence 1 chrX Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
MED21-201 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 8 46 2 2 0
MGST2-201 MGST2 Q99735 Microsomal glutathione S-transferase 2 chr4 Not Cancer Driver No 1 hippie 9 0 0 0 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MLC1-201 MLC1 Q15049 Membrane protein MLC1 chr22 Not Cancer Driver No 1 hippie, biogrid 38 35 7 7 14
MLH1-201 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 Census Yes 1 hippie, biogrid 65 208 13 13 77
MTRF1-203 MTRF1 O75570 Peptide chain release factor 1, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 33 72 4 4 0
MUS81-201 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 Not Cancer Driver No 1 hippie, biogrid 47 235 25 25 0
NAPA-201 NAPA P54920 Alpha-soluble NSF attachment protein chr19 Not Cancer Driver No 2 hippie, biogrid 19 11 0 0 0
NAPG-201 NAPG Q99747 Gamma-soluble NSF attachment protein chr18 Not Cancer Driver No 1 hippie, biogrid 25 57 2 2 0
NCAPD3-212 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 145 305 35 35 1
NELFE-202 NELFE P18615 Negative elongation factor E chr6 Not Cancer Driver No 1 hippie, biogrid 39 352 37 37 0
NEMP1-201 NEMP1 O14524 Nuclear envelope integral membrane protein 1 chr12 Not Cancer Driver No 1 hippie 22 36 3 3 0
NIPAL1-201 NIPAL1 Q6NVV3 Magnesium transporter NIPA3 chr4 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NRSN1-204 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 41 18 6 6 0
OCLN-202 OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 44 244 18 18 1
PANX1-201 PANX1 Q96RD7 Pannexin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 45 5 5 2
PDZK1IP1-201 PDZK1IP1 Q13113 PDZK1-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 13 21 0 0 0
PI4K2A-201 PI4K2A Q9BTU6 Phosphatidylinositol 4-kinase type 2-alpha chr10 Not Cancer Driver No 1 hippie, biogrid 32 130 4 4 0
PIGO-203 PIGO Q8TEQ8 GPI ethanolamine phosphate transferase 3 chr9 Not Cancer Driver No 1 hippie, biogrid 104 141 13 13 5
PINX1-201 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 Not Cancer Driver No 1 hippie 37 329 38 38 0
PLEKHO1-201 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 Not Cancer Driver No 1 hippie 44 343 36 36 0
PMAIP1-202 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
PMS1-213 PMS1 P54277 PMS1 protein homolog 1 chr2 Census Yes 1 hippie, biogrid 86 284 31 31 0
PPM1H-201 PPM1H Q9ULR3 Protein phosphatase 1H chr12 Not Cancer Driver No 1 hippie 60 141 25 25 0
PRKAB1-201 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 21 125 11 11 0
PTGES-201 PTGES O14684 Prostaglandin E synthase chr9 Not Cancer Driver No 1 hippie 6 0 0 0 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 36 141 17 17 0
RAB11A-201 RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 2 hippie, biogrid 12 43 2 2 0
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 15 58 3 3 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RAB3B-201 RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie, biogrid 26 26 6 6 0
RAB4A-201 RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 15 32 8 8 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 2 hippie, biogrid 20 67 9 9 0
RAB5C-201 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 17 51 2 2 0
RAB8A-201 RAB8A P61006 Ras-related protein Rab-8A chr19 Not Cancer Driver No 1 hippie 30 26 3 3 0
RAB9A-202 RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 2 hippie, biogrid 7 21 0 0 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 61 2 0 0 6
RAC2-201 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 24 0 0 0 2
RAC3-201 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 4
RET-202 RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 biogrid 176 108 11 11 91
RETREG3-201 RETREG3 Q86VR2 Reticulophagy regulator 3 chr17 Not Cancer Driver No 1 hippie 33 251 27 27 0
RHBDD1-202 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 Not Cancer Driver No 1 hippie 29 69 8 8 0
RHBDF2-201 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 Not Cancer Driver No 1 hippie 73 289 27 27 2
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 50 20 1 1 0
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RHOD-201 RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 16 10 0 0 0
RHOF-201 RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 15 11 0 0 0
RHOG-201 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 20 22 3 3 0
RHOH-201 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 32 12 3 3 0
RHOJ-201 RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 31 0 0 0 0
RHOQ-201 RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 19 0 0 0 0
RHOU-201 RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 28 63 6 6 0
RHOV-201 RHOV Q96L33 Rho-related GTP-binding protein RhoV chr15 Not Cancer Driver No 1 hippie 17 48 5 5 0
RINT1-201 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 2 hippie, biogrid 58 55 2 2 2
RMDN3-202 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie 33 198 14 14 0
RND1-201 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 Not Cancer Driver No 1 hippie 35 9 1 1 0
RND2-202 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 17 54 4 4 0
RND3-201 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 23 70 7 7 0
RNF11-201 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie, biogrid 11 78 6 6 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 2 hippie, biogrid 30 103 12 12 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RPL35A-211 RPL35A P18077 Large ribosomal subunit protein eL33 chr3 Not Cancer Driver No 1 hippie, biogrid 5 25 0 0 1
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 26 3 3 0
RPS6KA2-201 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 Not Cancer Driver No 1 hippie 110 92 13 13 0
RYBP-201 RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 23 202 22 22 0
SAR1A-204 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 Not Cancer Driver No 1 hippie 14 4 0 0 0
SCAMP5-202 SCAMP5 Q8TAC9 Secretory carrier-associated membrane protein 5 chr15 Not Cancer Driver No 1 hippie 31 2 1 1 0
SCARB2-201 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 2 hippie, biogrid 46 13 3 3 1
SCGN-201 SCGN O76038 Secretagogin chr6 Not Cancer Driver No 1 hippie, biogrid 46 12 1 1 0
SCN3B-201 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 1 hippie 45 16 2 2 3
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 6 60 5 5 0
SERBP1-204 SERBP1 Q8NC51 SERPINE1 mRNA-binding protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 40 408 40 40 0
SERINC2-201 SERINC2 Q96SA4 Serine incorporator 2 chr1 Not Cancer Driver No 1 hippie, biogrid 36 6 0 0 0
SETDB1-201 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 1 hippie 133 598 62 62 0
SFT2D1-201 SFT2D1 Q8WV19 Vesicle transport protein SFT2A chr6 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 0
SLC10A1-201 SLC10A1 Q14973 Hepatic sodium/bile acid cotransporter chr14 Not Cancer Driver No 1 hippie 32 0 0 0 5
SLC16A2-201 SLC16A2 P36021 Monocarboxylate transporter 8 chrX Not Cancer Driver No 1 hippie 65 126 6 6 18
SLC3A2-203 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 44 171 7 7 0
SLCO1B1-201 SLCO1B1 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 chr12 Not Cancer Driver No 2 hippie, biogrid 143 33 3 3 0
SNAP23-201 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 1 hippie 12 180 10 10 0
SNAP29-201 SNAP29 O95721 Synaptosomal-associated protein 29 chr22 Not Cancer Driver No 2 hippie, biogrid 19 249 19 19 0
SNAP47-213 SNAP47 Q5SQN1 Synaptosomal-associated protein 47 chr1 Not Cancer Driver No 1 hippie 38 151 15 15 0
SNRNP27-201 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 2 hippie, biogrid 5 155 5 5 0
SPAST-201 SPAST Q9UBP0 Spastin chr2 Not Cancer Driver No 1 hippie, biogrid 52 270 16 16 62
SRGAP3-202 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 1 hippie, biogrid 166 551 87 87 0
STX11-201 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 2 hippie, biogrid 51 49 5 5 0
STX12-201 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 3 hippie, biogrid 13 156 6 6 0
STX16-206 STX16 O14662 Syntaxin-16 chr20 Not Cancer Driver No 1 hippie 36 120 10 10 0
STX18-201 STX18 Q9P2W9 Syntaxin-18 chr4 Not Cancer Driver No 1 hippie, biogrid 23 176 12 12 0
STX19-201 STX19 Q8N4C7 Syntaxin-19 chr3 Not Cancer Driver No 3 hippie, biogrid 28 67 3 3 0
STX1A-201 STX1A Q16623 Syntaxin-1A chr7 Not Cancer Driver No 1 hippie 29 138 11 11 0
STX2-203 STX2 P32856 Syntaxin-2 chr12 Not Cancer Driver No 1 hippie 32 142 19 19 0
STX3-201 STX3 Q13277 Syntaxin-3 chr11 Not Cancer Driver No 4 hippie, biogrid 37 130 24 24 0
STX4-201 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 2 hippie, biogrid 39 153 16 16 0
STX6-201 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 5 hippie, biogrid 25 78 9 9 0
STX7-202 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 5 hippie, biogrid 21 165 9 9 0
STX8-201 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 2 hippie, biogrid 16 99 5 5 0
STYK1-201 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 biogrid 67 35 7 7 0
SYPL1-201 SYPL1 Q16563 Synaptophysin-like protein 1 chr7 Not Cancer Driver No 2 hippie, biogrid 27 17 3 3 0
SYPL2-201 SYPL2 Q5VXT5 Synaptophysin-like protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 24 48 4 4 0
SYT6-209 SYT6 Q5T7P8 Synaptotagmin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 63 137 12 12 0
TCTN2-201 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 hippie 62 23 2 2 0
TEX101-201 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 39 2 0 0 0
TFRC-201 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie, biogrid 66 80 4 4 1
TGFA-201 TGFA P01135 Protransforming growth factor alpha chr2 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
TGOLN2-201 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 hippie 39 401 33 33 0
TIMMDC1-208 TIMMDC1 Q9NPL8 Complex I assembly factor TIMMDC1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 37 51 4 4 0
TINF2-201 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 Not Cancer Driver No 1 hippie 29 190 13 13 3
TM4SF19-201 TM4SF19 Q96DZ7 Transmembrane 4 L6 family member 19 chr3 Not Cancer Driver No 1 hippie 19 0 0 0 0
TM4SF19-DYNLT2B-201 TM4SF19 Q96DZ7 Transmembrane 4 L6 family member 19 chr3 Not Cancer Driver No 1 hippie 19 0 0 0 0
TM4SF20-201 TM4SF20 Q53R12 Transmembrane 4 L6 family member 20 chr2 Not Cancer Driver No 1 hippie 15 4 0 0 0
TM4SF5-201 TM4SF5 O14894 Transmembrane 4 L6 family member 5 chr17 Not Cancer Driver No 1 hippie, biogrid 24 1 0 0 0
TMEM17-201 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 hippie 15 14 1 1 0
TMEM216-203 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 hippie 7 0 0 0 5
TMEM237-203 TMEM237 Q96Q45 Transmembrane protein 237 chr2 Not Cancer Driver No 1 hippie 28 178 14 14 0
TMEM31-201 TMEM31 Q5JXX7 Transmembrane protein 31 chrX Not Cancer Driver No 1 hippie 16 61 6 6 0
TMEM35A-201 TMEM35A Q53FP2 Novel acetylcholine receptor chaperone chrX Not Cancer Driver No 1 hippie 22 23 6 6 0
TMEM52B-204 TMEM52B Q4KMG9 Transmembrane protein 52B chr12 Not Cancer Driver No 1 hippie 29 34 9 9 0
TMEM63C-201 TMEM63C Q9P1W3 Calcium permeable stress-gated cation channel 1 chr14 Not Cancer Driver No 1 hippie, biogrid 84 85 10 10 0
TMEM86B-201 TMEM86B Q8N661 Lysoplasmalogenase chr19 Not Cancer Driver No 1 hippie 14 1 0 0 0
TMEM98-206 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 Not Cancer Driver No 1 hippie, biogrid 29 28 2 2 2
TMPPE-201 TMPPE Q6ZT21 Transmembrane protein with metallophosphoesterase domain chr3 Not Cancer Driver No 1 hippie 30 19 0 0 0
TMX2-201 TMX2 Q9Y320 Thioredoxin-related transmembrane protein 2 chr11 Not Cancer Driver No 1 hippie 34 40 5 5 3
TNFRSF10B-201 TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 Not Cancer Driver No 3 hippie, biogrid 36 192 15 15 0
TNFRSF10C-201 TNFRSF10C O14798 Tumor necrosis factor receptor superfamily member 10C chr8 Not Cancer Driver No 1 hippie, biogrid 24 120 13 13 0
TPCN2-201 TPCN2 Q8NHX9 Two pore channel protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 43 16 0 0 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TSPAN31-201 TSPAN31 Q12999 Tetraspanin-31 chr12 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
UBA5-202 UBA5 Q9GZZ9 Ubiquitin-like modifier-activating enzyme 5 chr3 Not Cancer Driver No 1 hippie, biogrid 26 127 6 6 7
UBD-203 UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 24 8 1 1 0
USE1-201 USE1 Q9NZ43 Vesicle transport protein USE1 chr19 Not Cancer Driver No 1 hippie, biogrid 27 102 19 19 0
USP47-203 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 Not Cancer Driver No 2 hippie, biogrid 86 426 24 24 0
VAC14-201 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 1 hippie, biogrid 76 117 17 17 3
VAMP2-201 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 Not Cancer Driver No 1 hippie 3 47 0 0 3
VAMP5-201 VAMP5 O95183 Vesicle-associated membrane protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 13 19 1 1 0
VAMP8-201 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 Not Cancer Driver No 1 hippie 7 27 1 1 0
VEGFD-201 VEGFD O43915 Vascular endothelial growth factor D chrX Not Cancer Driver No 1 hippie 38 33 4 4 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 intact, hippie 85 117 15 15 84
VPS50-202 VPS50 Q96JG6 Syndetin chr7 Not Cancer Driver No 1 hippie 116 171 22 22 0
VSIR-201 VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 Not Cancer Driver No 1 hippie 41 135 15 15 0
VTI1A-201 VTI1A Q96AJ9 Vesicle transport through interaction with t-SNAREs homolog 1A chr10 Census Yes 1 hippie 14 138 8 8 0
VTI1B-204 VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 Not Cancer Driver No 3 hippie, biogrid 14 195 12 12 0
WDFY1-201 WDFY1 Q8IWB7 WD repeat and FYVE domain-containing protein 1 chr2 Not Cancer Driver No 2 hippie, biogrid 36 24 1 1 0
WDFY2-201 WDFY2 Q96P53 WD repeat and FYVE domain-containing protein 2 chr13 Not Cancer Driver No 3 hippie, biogrid 38 20 2 2 0
YWHAG-201 YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 21 78 4 4 3
ZC4H2-202 ZC4H2 Q9NQZ6 Zinc finger C4H2 domain-containing protein chrX Not Cancer Driver No 1 hippie, biogrid 51 136 34 34 11
ZDHHC5-201 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 66 463 46 46 0
ZFPL1-201 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 127 16 16 0
ZMYM6-202 ZMYM6 O95789 Zinc finger MYM-type protein 6 chr1 Not Cancer Driver No 1 hippie, biogrid 96 230 21 21 0
ZSCAN21-201 ZSCAN21 Q9Y5A6 Zinc finger and SCAN domain-containing protein 21 chr7 Not Cancer Driver No 1 hippie, biogrid 52 252 28 28 0