Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABT1-201 | ABT1 | Q9ULW3 | Activator of basal transcription 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 157 | 17 | 17 | 0 |
| AFDN-211 | AFDN | P55196 | Afadin | chr6 | Census | Yes | 1 | hippie | 162 | 1247 | 123 | 123 | 0 |
| ANKRD36B-202 | ANKRD36B | Q8N2N9 | Ankyrin repeat domain-containing protein 36B | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 0 | 812 | 0 | 0 | 0 |
| ANLN-201 | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie | 101 | 771 | 75 | 75 | 2 |
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 23 | 104 | 9 | 9 | 0 |
| ARF6-201 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 5 | 0 | 0 | 0 |
| ARGLU1-203 | ARGLU1 | Q9NWB6 | Arginine and glutamate-rich protein 1 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 246 | 14 | 14 | 0 |
| ATP2A1-201 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 80 | 9 | 9 | 1 |
| B3GAT1-201 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 93 | 24 | 24 | 0 |
| BCAP31-201 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 104 | 13 | 13 | 0 |
| BET1-201 | BET1 | O15155 | BET1 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 8 | 7 | 2 | 2 | 0 |
| BRAF-220 | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | Census, Compendium | Yes | 1 | hippie | 755 | 311 | 30 | 30 | 35 |
| BRD2-201 | BRD2 | P25440 | Bromodomain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 82 | 632 | 63 | 63 | 0 |
| BRD3-201 | BRD3 | Q15059 | Bromodomain-containing protein 3 | chr9 | Census | Yes | 1 | hippie | 64 | 567 | 53 | 53 | 0 |
| C11orf52-201 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 109 | 11 | 11 | 0 |
| CA9-201 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 56 | 276 | 40 | 40 | 0 |
| CAMKV-209 | CAMKV | Q8NCB2 | CaM kinase-like vesicle-associated protein | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 226 | 22 | 22 | 0 |
| CAV1-201 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 2 | 0 | 0 | 0 |
| CCDC8-201 | CCDC8 | Q9H0W5 | Coiled-coil domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 63 | 509 | 62 | 62 | 0 |
| CD3E-201 | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 72 | 6 | 6 | 0 |
| CD44-208 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 58 | 547 | 50 | 50 | 0 |
| CD6-201 | CD6 | P30203 | T-cell differentiation antigen CD6 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 270 | 36 | 36 | 0 |
| CD82-201 | CD82 | P27701 | CD82 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 14 | 3 | 3 | 0 |
| CD83-201 | CD83 | Q01151 | CD83 antigen | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 23 | 49 | 8 | 8 | 0 |
| CDC42-208 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| CKAP4-201 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 412 | 36 | 36 | 0 |
| COX8A-201 | COX8A | P10176 | Cytochrome c oxidase subunit 8A, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 1 | 0 | 0 | 0 |
| CREB3-201 | CREB3 | O43889 | Cyclic AMP-responsive element-binding protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 25 | 169 | 7 | 7 | 0 |
| CXADR-201 | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 99 | 15 | 15 | 0 |
| CYBC1-201 | CYBC1 | Q9BQA9 | Cytochrome b-245 chaperone 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 16 | 17 | 2 | 2 | 0 |
| DERL1-201 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 12 | 0 | 0 | 0 |
| DIRAS3-202 | DIRAS3 | O95661 | GTP-binding protein Di-Ras3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 21 | 2 | 2 | 0 |
| DLG1-269 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 89 | 460 | 48 | 48 | 0 |
| DNAJC1-202 | DNAJC1 | Q96KC8 | DnaJ homolog subfamily C member 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 315 | 38 | 38 | 0 |
| DNAJC16-202 | DNAJC16 | Q9Y2G8 | DnaJ homolog subfamily C member 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 64 | 2 | 2 | 0 |
| DNAJC25-201 | DNAJC25 | Q9H1X3 | DnaJ homolog subfamily C member 25 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 39 | 3 | 3 | 0 |
| DNAJC5-201 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 46 | 5 | 5 | 1 |
| DNAJC5B-201 | DNAJC5B | Q9UF47 | DnaJ homolog subfamily C member 5B | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 31 | 5 | 5 | 0 |
| DPP4-201 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 8 | 0 | 0 | 0 |
| DVL1-201 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 42 | 434 | 16 | 16 | 0 |
| DVL2-201 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 72 | 515 | 52 | 52 | 0 |
| DVL3-201 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 58 | 437 | 31 | 31 | 0 |
| DYRK2-202 | DYRK2 | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 60 | 294 | 33 | 33 | 0 |
| EBAG9-201 | EBAG9 | O00559 | Receptor-binding cancer antigen expressed on SiSo cells | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 175 | 25 | 25 | 0 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | biogrid | 346 | 223 | 30 | 30 | 1 |
| EIF3L-215 | EIF3L | Q9Y262 | Eukaryotic translation initiation factor 3 subunit L | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 41 | 1 | 1 | 0 |
| ELOVL5-201 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 25 | 2 | 2 | 2 |
| EMD-202 | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 29 | 160 | 18 | 18 | 3 |
| EMP3-201 | EMP3 | P54852 | Epithelial membrane protein 3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 0 | 0 | 0 | 0 |
| ENST00000695856 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 21 | 23 | 1 | 1 | 1 |
| EPB41L1-202 | EPB41L1 | Q9H4G0 | Band 4.1-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 579 | 93 | 93 | 1 |
| EPB41L3-201 | EPB41L3 | Q9Y2J2 | Band 4.1-like protein 3 | chr18 | Not Cancer Driver | No | 2 | hippie, biogrid | 240 | 697 | 165 | 165 | 0 |
| EPB41L4A-201 | EPB41L4A | Q9HCS5 | Band 4.1-like protein 4A | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 380 | 41 | 41 | 0 |
| EPB41L5-201 | EPB41L5 | Q9HCM4 | Band 4.1-like protein 5 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 68 | 315 | 32 | 32 | 0 |
| EPHA2-201 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | Compendium | Yes | 1 | biogrid | 147 | 188 | 33 | 33 | 3 |
| EPHA3-201 | EPHA3 | P29320 | Ephrin type-A receptor 3 | chr3 | Census, Compendium | Yes | 1 | biogrid | 285 | 74 | 26 | 26 | 0 |
| EPHA4-201 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | Not Cancer Driver | No | 1 | biogrid | 132 | 141 | 16 | 16 | 0 |
| EPHA5-201 | EPHA5 | P54756 | Ephrin type-A receptor 5 | chr4 | Not Cancer Driver | No | 1 | biogrid | 296 | 84 | 24 | 24 | 0 |
| ERBB4-202 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | Census, Compendium | Yes | 1 | hippie | 376 | 324 | 95 | 95 | 2 |
| ERGIC1-202 | ERGIC1 | Q969X5 | Endoplasmic reticulum-Golgi intermediate compartment protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 26 | 0 | 0 | 0 |
| ERMAP-203 | ERMAP | Q96PL5 | Erythroid membrane-associated protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 48 | 3 | 3 | 0 |
| ESR1-201 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 92 | 198 | 19 | 19 | 2 |
| ESR2-202 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 69 | 92 | 10 | 10 | 1 |
| EVC2-202 | EVC2 | Q86UK5 | Limbin | chr4 | Not Cancer Driver | No | 1 | hippie | 184 | 340 | 56 | 56 | 2 |
| EZR-202 | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | hippie, biogrid | 51 | 296 | 26 | 26 | 0 |
| FBXL19-204 | FBXL19 | Q6PCT2 | F-box/LRR-repeat protein 19 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 350 | 30 | 30 | 0 |
| FBXW11-201 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | Not Cancer Driver | No | 1 | hippie | 41 | 20 | 2 | 2 | 6 |
| FGF8-202 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 27 | 79 | 8 | 8 | 6 |
| FGFBP1-201 | FGFBP1 | Q14512 | Fibroblast growth factor-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 81 | 8 | 8 | 0 |
| FGFR1-214 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | Census, Compendium | Yes | 1 | biogrid | 92 | 231 | 26 | 26 | 69 |
| FGFR2-206 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | Census, Compendium | Yes | 1 | biogrid | 193 | 229 | 34 | 34 | 57 |
| FGFR4-201 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | Census, Compendium | Yes | 1 | biogrid | 101 | 163 | 27 | 27 | 0 |
| FKBP8-206 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 161 | 19 | 19 | 0 |
| FLOT1-201 | FLOT1 | O75955 | Flotillin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 122 | 10 | 10 | 0 |
| FMR1-205 | FMR1 | Q06787 | Fragile X messenger ribonucleoprotein 1 | chrX | Not Cancer Driver | No | 1 | hippie | 92 | 327 | 50 | 50 | 3 |
| GJA1-201 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 111 | 20 | 20 | 43 |
| GJD3-201 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 2 | 80 | 0 | 0 | 0 |
| GMFG-206 | GMFG | O60234 | Glia maturation factor gamma | chr19 | Not Cancer Driver | No | 1 | hippie | 17 | 10 | 1 | 1 | 0 |
| GPR156-202 | GPR156 | Q8NFN8 | Probable G-protein coupled receptor 156 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 91 | 419 | 55 | 55 | 0 |
| HADHA-201 | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 19 | 0 | 0 | 5 |
| HDGFL2-208 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 622 | 26 | 26 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 129 | 16 | 2 | 2 | 10 |
| HSD17B11-201 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 2 | 0 | 0 | 0 |
| HSD3B7-202 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 27 | 4 | 4 | 2 |
| HSPA12A-201 | HSPA12A | O43301 | Heat shock 70 kDa protein 12A | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 88 | 12 | 12 | 0 |
| HSPA12B-201 | HSPA12B | Q96MM6 | Heat shock 70 kDa protein 12B | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 128 | 16 | 16 | 0 |
| IL7R-201 | IL7R | P16871 | Interleukin-7 receptor subunit alpha | chr5 | Census, Compendium | Yes | 1 | hippie, biogrid | 140 | 89 | 40 | 40 | 1 |
| INAVA-201 | INAVA | Q3KP66 | Innate immunity activator protein | chr1 | Not Cancer Driver | No | 1 | hippie | 64 | 570 | 52 | 52 | 1 |
| INO80E-207 | INO80E | Q8NBZ0 | INO80 complex subunit E | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 211 | 15 | 15 | 0 |
| JPH4-201 | JPH4 | Q96JJ6 | Junctophilin-4 | chr14 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 48 | 517 | 47 | 47 | 0 |
| KBTBD7-201 | KBTBD7 | Q8WVZ9 | Kelch repeat and BTB domain-containing protein 7 | chr13 | Not Cancer Driver | No | 1 | hippie | 63 | 107 | 6 | 6 | 0 |
| KCNE3-201 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| KIR2DL1-202 | KIR2DL1 | P43626 | Killer cell immunoglobulin-like receptor 2DL1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 92 | 125 | 39 | 39 | 0 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | hippie, biogrid | 771 | 7 | 2 | 2 | 22 |
| LAMP1-201 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 94 | 8 | 8 | 0 |
| LAMP2-201 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 55 | 4 | 4 | 1 |
| LAMP3-201 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 223 | 34 | 34 | 0 |
| LAMTOR1-201 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 96 | 6 | 6 | 0 |
| LCK-202 | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | Census | Yes | 1 | hippie, biogrid | 76 | 95 | 12 | 12 | 1 |
| LGALS1-201 | LGALS1 | P09382 | Galectin-1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
| LGALS8-206 | LGALS8 | O00214 | Galectin-8 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 32 | 3 | 3 | 0 |
| LMAN1-201 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 223 | 18 | 18 | 1 |
| LNPK-201 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 48 | 256 | 34 | 34 | 0 |
| LRRC59-201 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 123 | 13 | 13 | 0 |
| LUC7L-201 | LUC7L | Q9NQ29 | Putative RNA-binding protein Luc7-like 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 254 | 7 | 7 | 0 |
| LYN-202 | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie, biogrid | 78 | 85 | 10 | 10 | 0 |
| MANSC1-202 | MANSC1 | Q9H8J5 | MANSC domain-containing protein 1 | chr12 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 38 | 209 | 14 | 14 | 0 |
| MARCKS-201 | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 328 | 5 | 5 | 0 |
| MAST1-201 | MAST1 | Q9Y2H9 | Microtubule-associated serine/threonine-protein kinase 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 160 | 1081 | 99 | 99 | 1 |
| MYO6-202 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 335 | 9 | 9 | 3 |
| NAF1-201 | NAF1 | Q96HR8 | H/ACA ribonucleoprotein complex non-core subunit NAF1 | chr4 | Not Cancer Driver | No | 1 | hippie | 48 | 388 | 33 | 33 | 0 |
| NBR1-206 | NBR1 | Q14596 | Next to BRCA1 gene 1 protein | chr17 | Not Cancer Driver | No | 1 | hippie | 88 | 562 | 41 | 41 | 0 |
| NFKBIL1-203 | NFKBIL1 | Q9UBC1 | NF-kappa-B inhibitor-like protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 316 | 26 | 26 | 0 |
| NRAS-201 | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 272 | 10 | 0 | 0 | 12 |
| NT5C3A-209 | NT5C3A | Q9H0P0 | Cytosolic 5'-nucleotidase 3A | chr7 | Compendium | Yes | 1 | hippie | 26 | 0 | 0 | 0 | 8 |
| NTRK1-206 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | biogrid | 133 | 57 | 8 | 8 | 23 |
| NTRK2-246 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | Not Cancer Driver | No | 1 | biogrid | 103 | 117 | 14 | 14 | 1 |
| NTRK3-217 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | Census, Compendium | Yes | 1 | biogrid | 214 | 56 | 15 | 15 | 3 |
| NUAK2-201 | NUAK2 | Q9H093 | NUAK family SNF1-like kinase 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 344 | 48 | 48 | 0 |
| NXF2-202 | NXF2B | Q9GZY0 | Nuclear RNA export factor 2 | chrX | Not Cancer Driver | No | 1 | intact | 40 | 125 | 5 | 5 | 0 |
| NXF2B-202 | NXF2B | Q9GZY0 | Nuclear RNA export factor 2 | chrX | Not Cancer Driver | No | 1 | intact | 40 | 125 | 5 | 5 | 0 |
| OCLN-202 | OCLN | Q16625 | Occludin | chr5 | Not Cancer Driver | No | 1 | biogrid | 44 | 244 | 18 | 18 | 1 |
| OTULINL-201 | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 21 | 0 | 0 | 0 |
| PANX1-201 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 45 | 5 | 5 | 2 |
| PARD3-208 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 148 | 1147 | 128 | 128 | 2 |
| PLCD3-212 | PLCD3 | Q8N3E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 231 | 18 | 18 | 0 |
| PNN-201 | PNN | Q9H307 | Pinin | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 51 | 701 | 48 | 48 | 0 |
| PRG2-201 | PRG2 | P13727 | Bone marrow proteoglycan | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 66 | 13 | 13 | 0 |
| PRICKLE3-206 | PRICKLE3 | O43900 | Prickle planar cell polarity protein 3 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 64 | 277 | 31 | 31 | 1 |
| PRKACA-201 | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | Census | Yes | 1 | hippie, biogrid | 49 | 24 | 0 | 0 | 2 |
| PTPN1-201 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 141 | 17 | 17 | 0 |
| PTPN3-202 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 105 | 214 | 24 | 24 | 0 |
| PXMP2-201 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 0 | 0 | 0 | 0 |
| RAB11A-201 | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 43 | 2 | 2 | 0 |
| RAB2A-201 | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 58 | 3 | 3 | 0 |
| RAB35-201 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 26 | 1 | 1 | 0 |
| RAB3B-201 | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 26 | 6 | 6 | 0 |
| RAB4A-201 | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 32 | 8 | 8 | 0 |
| RAB5A-201 | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 67 | 9 | 9 | 0 |
| RAB5C-201 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 51 | 2 | 2 | 0 |
| RAB7A-201 | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 19 | 11 | 0 | 0 | 4 |
| RAB9A-202 | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 21 | 0 | 0 | 0 |
| RAC1-201 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 61 | 2 | 0 | 0 | 6 |
| RAC2-201 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 2 |
| RAC3-201 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 4 |
| RAPGEF5-202 | RAPGEF5 | Q92565 | Rap guanine nucleotide exchange factor 5 | chr7 | Not Cancer Driver | No | 1 | hippie | 50 | 56 | 9 | 9 | 0 |
| RASSF10-201 | RASSF10 | A6NK89 | Ras association domain-containing protein 10 | chr11 | Not Cancer Driver | No | 1 | hippie | 0 | 373 | 0 | 0 | 0 |
| RASSF9-201 | RASSF9 | O75901 | Ras association domain-containing protein 9 | chr12 | Not Cancer Driver | No | 1 | hippie | 58 | 131 | 17 | 17 | 0 |
| RHBDD1-202 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 29 | 69 | 8 | 8 | 0 |
| RHBDF2-201 | RHBDF2 | Q6PJF5 | Inactive rhomboid protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 73 | 289 | 27 | 27 | 2 |
| RHOA-202 | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 92 | 46 | 12 | 12 | 2 |
| RHOB-201 | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 50 | 20 | 1 | 1 | 0 |
| RHOC-202 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 53 | 4 | 4 | 0 |
| RHOD-201 | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 10 | 0 | 0 | 0 |
| RHOF-201 | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 15 | 11 | 0 | 0 | 0 |
| RHOG-201 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 22 | 3 | 3 | 0 |
| RHOH-201 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 32 | 12 | 3 | 3 | 0 |
| RHOJ-201 | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 0 |
| RHOQ-201 | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 19 | 0 | 0 | 0 | 0 |
| RHOU-201 | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 63 | 6 | 6 | 0 |
| RHOV-201 | RHOV | Q96L33 | Rho-related GTP-binding protein RhoV | chr15 | Not Cancer Driver | No | 1 | hippie | 17 | 48 | 5 | 5 | 0 |
| RMDN3-202 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 198 | 14 | 14 | 0 |
| RND1-201 | RND1 | Q92730 | Rho-related GTP-binding protein Rho6 | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 9 | 1 | 1 | 0 |
| RND2-202 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 17 | 54 | 4 | 4 | 0 |
| RND3-201 | RND3 | P61587 | Rho-related GTP-binding protein RhoE | chr2 | Not Cancer Driver | No | 1 | hippie | 23 | 70 | 7 | 7 | 0 |
| RNF41-201 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | Not Cancer Driver | No | 1 | hippie | 36 | 33 | 2 | 2 | 0 |
| RNPS1-202 | RNPS1 | Q15287 | RNA-binding protein with serine-rich domain 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 305 | 5 | 5 | 0 |
| ROR1-201 | ROR1 | Q01973 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | chr1 | Not Cancer Driver | No | 1 | biogrid | 113 | 281 | 37 | 37 | 1 |
| ROR2-201 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | Not Cancer Driver | No | 1 | biogrid | 164 | 304 | 58 | 58 | 5 |
| RP9-201 | RP9 | Q8TA86 | Retinitis pigmentosa 9 protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 206 | 14 | 14 | 2 |
| RPL22-201 | RPL22 | P35268 | Large ribosomal subunit protein eL22 | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 19 | 15 | 0 | 0 | 0 |
| RPN1-201 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 32 | 69 | 3 | 3 | 0 |
| RPN2-201 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 26 | 3 | 3 | 0 |
| RPS24-214 | RPS24 | P62847 | Small ribosomal subunit protein eS24 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 89 | 5 | 5 | 0 |
| RPS6KA2-201 | RPS6KA2 | Q15349 | Ribosomal protein S6 kinase alpha-2 | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 92 | 13 | 13 | 0 |
| RYK-208 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | Not Cancer Driver | No | 1 | biogrid | 38 | 85 | 3 | 3 | 0 |
| SAP18-207 | SAP18 | O00422 | Histone deacetylase complex subunit SAP18 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 100 | 9 | 9 | 0 |
| SDC1-201 | SDC1 | P18827 | Syndecan-1 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 24 | 263 | 23 | 23 | 0 |
| SDC2-201 | SDC2 | P34741 | Syndecan-2 | chr8 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 33 | 130 | 21 | 21 | 0 |
| SDC4-201 | SDC4 | P31431 | Syndecan-4 | chr20 | Census, Compendium | Yes | 1 | hippie, biogrid | 20 | 111 | 15 | 15 | 0 |
| SEC61B-201 | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 6 | 60 | 5 | 5 | 0 |
| SEC62-201 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 211 | 9 | 9 | 0 |
| SEC63-201 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 267 | 25 | 25 | 0 |
| SIDT2-202 | SIDT2 | Q8NBJ9 | SID1 transmembrane family member 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 23 | 3 | 3 | 0 |
| SLC25A46-201 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 98 | 2 | 2 | 4 |
| SMYD3-214 | SMYD3 | Q9H7B4 | Histone-lysine N-methyltransferase SMYD3 | chr1 | Not Cancer Driver | No | 1 | hippie | 48 | 2 | 0 | 0 | 0 |
| SPRY2-202 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 170 | 19 | 19 | 1 |
| SRPK1-204 | SRPK1 | Q96SB4 | SRSF protein kinase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 52 | 329 | 21 | 21 | 0 |
| SSR1-201 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 115 | 5 | 5 | 0 |
| ST7-201 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 37 | 64 | 6 | 6 | 0 |
| STIM1-201 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 386 | 35 | 35 | 12 |
| STX4-201 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 153 | 16 | 16 | 0 |
| STX6-201 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 78 | 9 | 9 | 0 |
| STX7-202 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 165 | 9 | 9 | 0 |
| STYK1-201 | STYK1 | Q6J9G0 | Tyrosine-protein kinase STYK1 | chr12 | Not Cancer Driver | No | 1 | biogrid | 67 | 35 | 7 | 7 | 0 |
| SYNJ2BP-201 | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 12 | 1 | 1 | 0 |
| SYT12-205 | SYT12 | Q8IV01 | Synaptotagmin-12 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 74 | 10 | 10 | 0 |
| TCTN3-203 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | hippie | 32 | 71 | 5 | 5 | 1 |
| TGOLN2-201 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 39 | 401 | 33 | 33 | 0 |
| THAP2-201 | THAP2 | Q9H0W7 | THAP domain-containing protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 16 | 41 | 1 | 1 | 0 |
| TMEM17-201 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | hippie | 15 | 14 | 1 | 1 | 0 |
| TMEM216-203 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | hippie | 7 | 0 | 0 | 0 | 5 |
| TMPO-202 | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 414 | 32 | 32 | 0 |
| TNFRSF1A-201 | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 38 | 111 | 14 | 14 | 9 |
| TNFRSF1B-201 | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 231 | 21 | 21 | 0 |
| TRIM25-201 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 226 | 11 | 11 | 0 |
| TYROBP-201 | TYROBP | O43914 | TYRO protein tyrosine kinase-binding protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 29 | 6 | 6 | 0 |
| U2AF2-201 | U2AF2 | P26368 | Splicing factor U2AF 65 kDa subunit | chr19 | Compendium | Yes | 1 | hippie, biogrid | 61 | 191 | 24 | 24 | 0 |
| VANGL2-201 | VANGL2 | Q9ULK5 | Vang-like protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 79 | 150 | 13 | 13 | 3 |
| VCP-201 | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 74 | 186 | 14 | 14 | 12 |
| VIRMA-201 | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 157 | 634 | 73 | 73 | 0 |
| ZC3H18-201 | ZC3H18 | Q86VM9 | Zinc finger CCCH domain-containing protein 18 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 929 | 33 | 33 | 0 |
| ZCCHC10-207 | ZCCHC10 | Q8TBK6 | Zinc finger CCHC domain-containing protein 10 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 3 | 144 | 2 | 2 | 0 |
| ZFPL1-201 | ZFPL1 | O95159 | Zinc finger protein-like 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 127 | 16 | 16 | 0 |
| ZNF385C-205 | ZNF385C | Q66K41 | Zinc finger protein 385C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 0 | 0 | 0 | 0 | 0 |
| ZRANB2-202 | ZRANB2 | O95218 | Zinc finger Ran-binding domain-containing protein 2 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 19 | 257 | 11 | 11 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|