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WLS-201 ,WLS ,Q5T9L3
  • Number of Interaction partner in intact: 47
  • Number of Interaction partner in biogrid: 48
  • Number of Interaction partner in hippie: 117
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADORA2A-201 ADORA2A P29274 Adenosine receptor A2a chr22 Not Cancer Driver No 1 intact, hippie 42 93 8 8 0
AGMO-201 AGMO Q6ZNB7 Alkylglycerol monooxygenase chr7 Not Cancer Driver No 1 hippie 105 7 3 3 0
AQP4-201 AQP4 P55087 Aquaporin-4 chr18 Not Cancer Driver No 2 intact, hippie 39 30 5 5 0
ARF6-201 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 16 5 0 0 0
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
BORCS7-201 BORCS7 Q96B45 BLOC-1-related complex subunit 7 chr10 Not Cancer Driver No 1 intact, hippie 8 45 3 3 0
BORCS7-ASMT-201 BORCS7 Q96B45 BLOC-1-related complex subunit 7 chr10 Not Cancer Driver No 1 intact, hippie 8 45 3 3 0
C7orf25-201 C7orf25 Q9BPX7 UPF0415 protein C7orf25 chr7 Not Cancer Driver No 1 intact, hippie 30 66 4 4 0
CAP1-206 CAP1 Q01518 Adenylyl cyclase-associated protein 1 chr1 Not Cancer Driver No 1 intact, hippie 39 157 11 11 0
CCR2-201 CCR2 P41597 C-C chemokine receptor type 2 chr3 Not Cancer Driver No 1 intact, hippie 56 23 2 2 0
CD63-201 CD63 P08962 CD63 antigen chr12 Not Cancer Driver No 2 hippie, biogrid 17 0 0 0 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CGRRF1-201 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 Not Cancer Driver No 1 hippie 20 34 4 4 0
CHORDC1-201 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 37 119 12 12 0
CHP1-201 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 Not Cancer Driver No 1 intact 22 70 13 13 0
CHRNA4-201 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 Not Cancer Driver No 1 hippie, biogrid 112 188 26 26 1
CHRNB1-201 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 Not Cancer Driver No 1 hippie, biogrid 50 45 7 7 2
CHRND-201 CHRND Q07001 Acetylcholine receptor subunit delta chr2 Not Cancer Driver No 2 hippie, biogrid 87 71 18 18 7
CLEC4E-201 CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 2 hippie, biogrid 42 5 2 2 0
CNIH4-205 CNIH4 Q9P003 Protein cornichon homolog 4 chr1 Not Cancer Driver No 2 intact, hippie 11 0 0 0 0
DHFR2-201 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 13 20 0 0 0
DPM2-201 DPM2 O94777 Dolichol phosphate-mannose biosynthesis regulatory protein chr9 Not Cancer Driver No 1 intact, hippie 6 0 0 0 1
DRD2-202 DRD2 P14416 D(2) dopamine receptor chr11 Not Cancer Driver No 1 intact, hippie 91 124 31 31 0
DUOXA2-201 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
EBP-205 EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 intact, hippie 22 9 0 0 7
EMC7-201 EMC7 Q9NPA0 ER membrane protein complex subunit 7 chr15 Not Cancer Driver No 2 intact, hippie 22 54 4 4 0
ERLIN2-204 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 1 hippie 29 22 2 2 0
FAF2-201 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 36 171 11 11 0
FAM241B-201 FAM241B Q96D05 Protein FAM241B chr10 Not Cancer Driver No 1 intact, hippie 21 53 10 10 0
FCER1A-203 FCER1A P12319 High affinity immunoglobulin epsilon receptor subunit alpha chr1 Not Cancer Driver No 1 hippie, biogrid 64 13 0 0 0
FFAR1-201 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
GABRA3-201 GABRA3 P34903 Gamma-aminobutyric acid receptor subunit alpha-3 chrX Not Cancer Driver No 1 hippie, biogrid 103 48 7 7 2
GJD3-201 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 2 80 0 0 0
GPM6A-202 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 Not Cancer Driver No 1 intact, hippie 62 15 2 2 0
GPR182-201 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 38 33 5 5 0
GPR37-201 GPR37 O15354 Prosaposin receptor GPR37 chr7 Not Cancer Driver No 1 intact, hippie 92 204 29 29 0
HNRNPH1-203 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 44 169 20 20 1
HRAS-201 HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 129 16 2 2 10
HRH1-203 HRH1 P35367 Histamine H1 receptor chr3 Not Cancer Driver No 1 intact, hippie 65 122 16 16 0
HTR3A-205 HTR3A P46098 5-hydroxytryptamine receptor 3A chr11 Not Cancer Driver No 2 hippie, biogrid 90 45 12 12 0
HTR3C-201 HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C chr3 Not Cancer Driver No 3 hippie, biogrid 61 35 5 5 0
IRF2-201 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 1 hippie 60 290 52 52 0
KCNJ2-201 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 85 49 7 7 12
KCNK3-201 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 Not Cancer Driver No 1 intact 44 61 6 6 6
KMT2C-201 KMT2C Q8NEZ4 Histone-lysine N-methyltransferase 2C chr7 Census, Compendium Yes 1 intact, hippie 599 3606 368 368 0
KRAS-201 KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 771 7 2 2 22
LAMP3-201 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 57 223 34 34 0
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 10 96 6 6 0
LMBR1L-201 LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
LNPK-201 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 48 256 34 34 0
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
MOV10-203 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 90 103 6 6 0
NCSTN-201 NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 intact, hippie 69 72 10 10 1
NPC1-201 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 113 25 0 0 135
NRAS-201 NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 272 10 0 0 12
NXF1-201 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 85 163 28 28 0
OPRD1-201 OPRD1 P41143 Delta-type opioid receptor chr1 Not Cancer Driver No 1 hippie 53 30 2 2 0
OPRK1-201 OPRK1 P41145 Kappa-type opioid receptor chr8 Not Cancer Driver No 1 intact, hippie 97 18 5 5 0
OPRM1-202 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 4 intact, hippie 71 59 17 17 0
ORAI1-202 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 Not Cancer Driver No 1 intact, hippie 19 101 6 6 5
PCDHB10-201 PCDHB10 Q9UN67 Protocadherin beta-10 chr5 Not Cancer Driver No 2 intact, hippie 183 126 19 19 0
PEX11B-201 PEX11B O96011 Peroxisomal membrane protein 11B chr1 Not Cancer Driver No 1 hippie 22 22 3 3 0
PIGW-204 PIGW Q7Z7B1 Phosphatidylinositol-glycan biosynthesis class W protein chr17 Not Cancer Driver No 2 intact, hippie 25 0 0 0 2
POMK-201 POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 intact, hippie, biogrid 40 30 7 7 3
PORCN-201 PORCN Q9H237 Protein-serine O-palmitoleoyltransferase porcupine chrX Not Cancer Driver No 1 hippie 61 0 0 0 13
RAB2A-201 RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 15 58 3 3 0
RAB35-201 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 16 26 1 1 0
RAB4A-201 RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 15 32 8 8 0
RAB5A-201 RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 20 67 9 9 0
RAB5C-201 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 17 51 2 2 0
RAB9A-202 RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 7 21 0 0 0
RHOA-202 RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 92 46 12 12 2
RHOB-201 RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 50 20 1 1 0
RHOC-202 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 23 53 4 4 0
RNF128-201 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX Not Cancer Driver No 1 hippie 46 123 11 11 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
RNF41-201 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 hippie 36 33 2 2 0
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 26 3 3 0
RPRM-201 RPRM Q9NS64 Protein reprimo chr2 Not Cancer Driver No 1 hippie, biogrid 24 1 0 0 0
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 6 60 5 5 0
SEC62-201 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 12 211 9 9 0
SGIP1-203 SGIP1 Q9BQI5 SH3-containing GRB2-like protein 3-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 168 563 127 127 0
SIDT2-202 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 Not Cancer Driver No 1 hippie, biogrid 75 23 3 3 0
SLC22A9-201 SLC22A9 Q8IVM8 Organic anion transporter 7 chr11 Not Cancer Driver No 1 hippie, biogrid 116 34 9 9 0
SLC6A3-201 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 Not Cancer Driver No 1 intact, hippie 131 31 5 5 2
SMO-201 SMO Q99835 Protein smoothened chr7 Census, Compendium Yes 1 hippie 88 242 20 20 1
SNX8-201 SNX8 Q9Y5X2 Sorting nexin-8 chr7 Not Cancer Driver No 1 hippie, biogrid 42 114 9 9 0
SOX9-201 SOX9 P48436 Transcription factor SOX-9 chr17 Compendium Yes 2 intact, hippie 69 497 66 66 13
STX4-201 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 39 153 16 16 0
STYK1-201 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 67 35 7 7 0
TCTN2-201 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 62 23 2 2 0
TCTN3-203 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 32 71 5 5 1
TMED6-201 TMED6 Q8WW62 Transmembrane emp24 domain-containing protein 6 chr16 Not Cancer Driver No 1 hippie, biogrid 20 43 2 2 0
TMEM134-201 TMEM134 Q9H6X4 Transmembrane protein 134 chr11 Not Cancer Driver No 1 intact, hippie 7 72 0 0 0
TMEM14A-201 TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 Not Cancer Driver No 1 hippie 6 0 0 0 0
TMEM160-201 TMEM160 Q9NX00 Transmembrane protein 160 chr19 Not Cancer Driver No 2 intact, hippie 3 46 0 0 0
TMEM230-201 TMEM230 Q96A57 Transmembrane protein 230 chr20 Not Cancer Driver No 1 intact, hippie 15 0 0 0 0
TMPRSS4-201 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 41 34 1 1 0
TOMM6-201 TOMM6 Q96B49 Mitochondrial import receptor subunit TOM6 homolog chr6 Not Cancer Driver No 1 intact, hippie 1 18 0 0 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 45 226 11 11 0
TVP23B-201 TVP23B Q9NYZ1 Golgi apparatus membrane protein TVP23 homolog B chr17 Not Cancer Driver No 2 intact, hippie 12 21 2 2 0
UBXN4-201 UBXN4 Q92575 UBX domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie 53 303 32 32 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 74 186 14 14 12
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie 25 36 4 4 0
VIPR1-201 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 27 10 0 0 0
WLS-201 WLS Q5T9L3 Protein wntless homolog chr1 Not Cancer Driver No 1 intact, hippie 43 14 1 1 4
WNT1-201 WNT1 P04628 Proto-oncogene Wnt-1 chr12 Not Cancer Driver No 1 hippie 20 25 0 0 8
WNT16-201 WNT16 Q9UBV4 Protein Wnt-16 chr7 Not Cancer Driver No 1 hippie, biogrid 37 29 5 5 0
WNT2-201 WNT2 P09544 Protein Wnt-2 chr7 Not Cancer Driver No 1 hippie, biogrid 53 11 1 1 0
WNT3A-201 WNT3A P56704 Protein Wnt-3a chr1 Not Cancer Driver No 3 intact, hippie, biogrid 60 37 2 2 0
WNT4-201 WNT4 P56705 Protein Wnt-4 chr1 Not Cancer Driver No 3 hippie, biogrid 25 39 2 2 5
WNT5A-201 WNT5A P41221 Protein Wnt-5a chr3 Not Cancer Driver No 3 intact, hippie, biogrid 42 0 0 0 2
WNT5B-202 WNT5B Q9H1J7 Protein Wnt-5b chr12 Not Cancer Driver No 1 intact, hippie 55 23 4 4 0
WNT7A-201 WNT7A O00755 Protein Wnt-7a chr3 Not Cancer Driver No 3 intact, hippie, biogrid 68 18 6 6 4
WNT7B-201 WNT7B P56706 Protein Wnt-7b chr22 Not Cancer Driver No 1 intact, hippie 41 11 1 1 0
WNT8A-202 WNT8A Q9H1J5 Protein Wnt-8a chr5 Not Cancer Driver No 1 hippie 36 3 0 0 0
WNT8B-201 WNT8B Q93098 Protein Wnt-8b chr10 Not Cancer Driver No 1 intact, hippie 39 27 4 4 0
WNT9A-201 WNT9A O14904 Protein Wnt-9a chr1 Not Cancer Driver No 1 intact, hippie 58 44 7 7 0
WNT9B-201 WNT9B O14905 Protein Wnt-9b chr17 Not Cancer Driver No 1 hippie 42 11 6 6 0
YIPF6-204 YIPF6 Q96EC8 Protein YIPF6 chrX Not Cancer Driver No 1 hippie 25 20 3 3 0