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ZMPSTE24-201 ,ZMPSTE24 ,O75844
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 99
  • Number of Interaction partner in hippie: 127
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD14A-201 ABHD14A Q9BUJ0 Protein ABHD14A chr3 Not Cancer Driver No 1 hippie, biogrid 18 18 3 3 0
ADCK5-201 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 hippie, biogrid 39 5 2 2 0
AGR2-203 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 14 20 1 1 1
AKAP1-202 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 77 541 50 50 0
AMPD2-218 AMPD2 Q01433 AMP deaminase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 68 239 23 23 3
APOC3-201 APOC3 P02656 Apolipoprotein C-III chr11 Not Cancer Driver No 1 hippie, biogrid 10 13 2 2 1
ARMCX3-203 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 29 77 7 7 0
ATG2A-201 ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact, hippie 175 891 104 104 0
ATP2A1-201 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 125 80 9 9 1
ATP6V1H-202 ATP6V1H Q9UI12 V-type proton ATPase subunit H chr8 Not Cancer Driver No 1 hippie, biogrid 52 35 2 2 0
B3GAT1-201 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 59 93 24 24 0
BAG3-201 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 30 572 30 30 7
BCAP31-201 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 27 104 13 13 0
CAPZA2-201 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie, biogrid 21 19 0 0 0
CD55-204 CD55 P08174 Complement decay-accelerating factor chr1 Not Cancer Driver No 1 hippie, biogrid 30 128 11 11 1
CDX1-201 CDX1 P47902 Homeobox protein CDX-1 chr5 Not Cancer Driver No 1 intact, hippie 16 243 12 12 0
CENPH-201 CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie, biogrid 20 85 6 6 0
CENPM-201 CENPM Q9NSP4 Centromere protein M chr22 Not Cancer Driver No 1 hippie, biogrid 7 1 0 0 0
CFTR-201 CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact 216 145 9 9 130
CLTC-201 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 132 71 5 5 1
COPZ2-210 COPZ2 Q9P299 Coatomer subunit zeta-2 chr17 Not Cancer Driver No 1 hippie, biogrid 14 39 0 0 0
COX8A-201 COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CYB5R3-201 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 8
CYP1A1-201 CYP1A1 P04798 Cytochrome P450 1A1 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 55 17 1 1 0
CYP2C9-201 CYP2C9 P11712 Cytochrome P450 2C9 chr10 Not Cancer Driver No 1 hippie, biogrid 94 36 12 12 0
DDOST-201 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 20 13 3 3 1
DNAL4-201 DNAL4 O96015 Dynein axonemal light chain 4 chr22 Not Cancer Driver No 1 hippie, biogrid 8 15 4 4 0
DUSP23-201 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 Not Cancer Driver No 1 hippie, biogrid 5 13 0 0 0
ELAVL1-201 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 54 43 5 5 0
EMC1-207 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 77 61 4 4 2
EMC2-201 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 38 29 2 2 0
EMC4-202 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 8 17 1 1 0
EMD-202 EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 29 160 18 18 3
FAM118B-209 FAM118B Q9BPY3 Protein FAM118B chr11 Not Cancer Driver No 1 hippie, biogrid 39 37 3 3 0
FAM20C-201 FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 Not Cancer Driver No 1 hippie 21 188 1 1 8
FDPS-202 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 2 hippie, biogrid 50 0 0 0 1
FGF12-207 FGF12 P61328 Fibroblast growth factor 12 chr3 Not Cancer Driver No 1 hippie, biogrid 62 104 30 30 1
FTSJ1-202 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 intact, hippie 31 89 8 8 0
GALNT2-201 GALNT2 Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 70 122 18 18 2
GDPD5-201 GDPD5 Q8WTR4 Glycerophosphodiester phosphodiesterase domain-containing protein 5 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 56 65 7 7 0
GJB7-203 GJB7 Q6PEY0 Gap junction beta-7 protein chr6 Not Cancer Driver No 1 intact, hippie, biogrid 15 0 0 0 0
GJD3-201 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 2 80 0 0 0
GPR21-201 GPR21 Q99679 Probable G-protein coupled receptor 21 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 24 2 0 0 0
GSX1-201 GSX1 Q9H4S2 GS homeobox 1 chr13 Not Cancer Driver No 1 hippie, biogrid 17 138 10 10 0
GTF2E2-201 GTF2E2 P29084 Transcription initiation factor IIE subunit beta chr8 Not Cancer Driver No 1 intact, hippie, biogrid 21 133 9 9 2
H1-5-201 H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 13 226 13 13 0
HADHB-201 HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 54 41 9 9 12
HK1-202 HK1 P19367 Hexokinase-1 chr10 Not Cancer Driver No 1 hippie, biogrid 90 76 13 13 6
HNRNPF-208 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 hippie, biogrid 48 106 15 15 0
HNRNPUL1-204 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 59 535 22 22 0
HSD17B11-201 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 23 2 0 0 0
HSD3B7-202 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 37 27 4 4 2
IFI16-201 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie, biogrid 102 422 61 61 0
IFITM3-201 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 7 19 2 2 0
IL19-205 IL19 Q9UHD0 Interleukin-19 chr1 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
IL7-201 IL7 P13232 Interleukin-7 chr8 Not Cancer Driver No 1 hippie, biogrid 19 19 3 3 0
ISG15-203 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
KCNA2-201 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 76 83 12 12 6
KCNMB3-201 KCNMB3 Q9NPA1 Calcium-activated potassium channel subunit beta-3 chr3 Not Cancer Driver No 1 hippie, biogrid 18 22 2 2 0
KIAA2013-201 KIAA2013 Q8IYS2 Uncharacterized protein KIAA2013 chr1 Not Cancer Driver No 1 hippie, biogrid 33 78 4 4 0
KLF16-201 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 12 206 7 7 0
KRTAP19-4-201 KRTAP19-4 Q3LI73 Keratin-associated protein 19-4 chr21 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
KRTAP19-7-201 KRTAP19-7 Q3SYF9 Keratin-associated protein 19-7 chr21 Not Cancer Driver No 1 hippie, biogrid 7 0 0 0 0
KRTAP6-1-201 KRTAP6-1 Q3LI64 Keratin-associated protein 6-1 chr21 Not Cancer Driver No 1 hippie, biogrid 0 0 0 0 0
LMNA-205 LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 50 547 34 34 117
LNPK-201 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 48 256 34 34 0
LRRC59-201 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 26 123 13 13 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 402 91 13 13 20
MED21-201 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 8 46 2 2 0
MGST3-205 MGST3 O14880 Glutathione S-transferase 3, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
MME-201 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 intact, hippie 156 40 17 17 4
MORF4L1-201 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 32 163 11 11 0
MRPL40-201 MRPL40 Q9NQ50 Large ribosomal subunit protein mL40 chr22 Not Cancer Driver No 1 hippie, biogrid 17 105 10 10 0
MRPS5-201 MRPS5 P82675 Small ribosomal subunit protein uS5m chr2 Not Cancer Driver No 1 hippie, biogrid 37 158 15 15 0
MS4A15-202 MS4A15 Q8N5U1 Membrane-spanning 4-domains subfamily A member 15 chr11 Not Cancer Driver No 1 hippie, biogrid 30 27 4 4 0
MYLK4-201 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 hippie, biogrid 49 78 9 9 0
MYO1B-204 MYO1B O43795 Unconventional myosin-Ib chr2 Not Cancer Driver No 1 hippie, biogrid 103 35 3 3 0
NDUFB7-201 NDUFB7 P17568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie, biogrid 14 66 6 6 0
NR3C1-203 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 55 364 20 20 11
NRM-203 NRM Q8IXM6 Nurim chr6 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 0
OPTN-202 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie, biogrid 47 475 40 40 6
OR51V1-201 OR51V1 Q9H2C8 Olfactory receptor 51V1 chr11 Not Cancer Driver No 1 hippie, biogrid 92 0 0 0 0
OTULINL-201 OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 34 21 0 0 0
PDIA4-204 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 61 147 18 18 0
PDLIM5-201 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 Not Cancer Driver No 1 hippie, biogrid 56 373 35 35 0
PKMYT1-201 PKMYT1 Q99640 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase chr16 Not Cancer Driver No 1 hippie, biogrid 28 228 14 14 0
PLEKHA4-201 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 115 690 110 110 0
PMAIP1-202 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
PMF1-202 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 7 76 1 1 0
PMF1-BGLAP-203 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 7 100 1 1 0
PRELID1-201 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 16 45 3 3 0
PTPN1-201 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 36 141 17 17 0
RAB10-201 RAB10 P61026 Ras-related protein Rab-10 chr2 Not Cancer Driver No 1 hippie, biogrid 12 28 1 1 0
RAB5C-201 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 17 51 2 2 0
RB1CC1-201 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 150 579 56 56 0
RNF130-205 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 Not Cancer Driver No 1 biogrid 32 43 2 2 0
RNF149-201 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 biogrid 30 103 12 12 0
RNF26-201 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 33 71 5 5 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 9 120 5 5 0
RPL35A-211 RPL35A P18077 Large ribosomal subunit protein eL33 chr3 Not Cancer Driver No 1 hippie, biogrid 5 25 0 0 1
RPN1-201 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 32 69 3 3 0
RPN2-201 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 26 3 3 0
S100A10-202 S100A10 P60903 Protein S100-A10 chr1 Not Cancer Driver No 1 hippie, biogrid 9 3 1 1 0
SEC61B-201 SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 2 hippie, biogrid 6 60 5 5 0
SEC62-201 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 12 211 9 9 0
SLC17A2-201 SLC17A2 O00624 Sodium-dependent phosphate transport protein 3 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 58 12 3 3 0
SLC18A1-202 SLC18A1 P54219 Chromaffin granule amine transporter chr8 Not Cancer Driver No 2 intact, hippie, biogrid 69 28 2 2 0
SLC2A5-202 SLC2A5 P22732 Solute carrier family 2, facilitated glucose transporter member 5 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 55 12 3 3 0
SLC39A3-201 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
SPATA48-201 SPATA48 A4D263 Spermatogenesis-associated protein 48 chr7 Not Cancer Driver No 1 hippie 22 285 10 10 0
SRGAP3-202 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 1 hippie, biogrid 166 551 87 87 0
ST7-201 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 37 64 6 6 0
STX8-201 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 1 hippie, biogrid 16 99 5 5 0
SYNE3-206 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 118 239 37 37 0
SYNJ2BP-201 SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 Not Cancer Driver No 1 hippie, biogrid 21 12 1 1 0
SYT6-209 SYT6 Q5T7P8 Synaptotagmin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 63 137 12 12 0
TCTN2-201 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 62 23 2 2 0
TCTN3-203 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 32 71 5 5 1
TECTB-204 TECTB Q96PL2 Beta-tectorin chr10 Not Cancer Driver No 1 hippie, biogrid 42 2 0 0 0
TMEM106B-202 TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 22 57 4 4 1
TMEM196-201 TMEM196 Q5HYL7 Transmembrane protein 196 chr7 Not Cancer Driver No 1 hippie, biogrid 27 16 2 2 0
TMEM43-201 TMEM43 Q9BTV4 Transmembrane protein 43 chr3 Not Cancer Driver No 1 hippie, biogrid 42 57 8 8 3
TMPRSS12-201 TMPRSS12 Q86WS5 Transmembrane protease serine 12 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 33 45 7 7 0
TNFRSF17-201 TNFRSF17 Q02223 Tumor necrosis factor receptor superfamily member 17 chr16 Census Yes 2 hippie, biogrid 17 1 0 0 0
TOMM6-201 TOMM6 Q96B49 Mitochondrial import receptor subunit TOM6 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 1 18 0 0 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2742 282 1364 1364 60
VAC14-201 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 2 hippie, biogrid 76 117 17 17 3
VDAC1-201 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 25 36 4 4 0
VIRMA-201 VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 157 634 73 73 0
WASHC3-201 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 hippie 18 100 5 5 0
WIF1-201 WIF1 Q9Y5W5 Wnt inhibitory factor 1 chr12 Census Yes 1 hippie, biogrid 62 30 4 4 0