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ZZZ3-202 ,ZZZ3 ,Q8IYH5
  • Number of Interaction partner in intact: 36
  • Number of Interaction partner in biogrid: 68
  • Number of Interaction partner in hippie: 116
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTC1-201 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 90 48 14 14 11
AFG3L2-201 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 38 162 5 5 17
ASH2L-201 ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 Not Cancer Driver No 1 hippie, biogrid 71 294 33 33 0
ATN1-202 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 hippie, biogrid 111 1176 109 109 5
BCAT1-201 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 Not Cancer Driver No 2 intact, hippie, biogrid 53 8 2 2 0
BLZF1-203 BLZF1 Q9H2G9 Golgin-45 chr1 Not Cancer Driver No 1 intact, hippie 37 220 17 17 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 167 1466 127 127 34
CARD8-231 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 41 130 5 5 1
CARD9-201 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 Not Cancer Driver No 1 intact, hippie 54 225 26 26 10
CBY2-201 CBY2 Q8NA61 Protein chibby homolog 2 chr13 Not Cancer Driver No 1 intact 73 343 56 56 0
CCT8L2-201 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 196 104 41 41 0
CDH19-201 CDH19 Q9H159 Cadherin-19 chr18 Not Cancer Driver No 2 hippie, biogrid 157 176 35 35 0
CDK8-201 CDK8 P49336 Cyclin-dependent kinase 8 chr13 Not Cancer Driver No 1 intact, hippie 53 152 14 14 7
CHMP4C-201 CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 226 31 31 0
CRYBG2-201 CRYBG2 Q8N1P7 Beta/gamma crystallin domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie 43 1092 9 9 0
CXXC1-201 CXXC1 Q9P0U4 CXXC-type zinc finger protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 89 368 51 51 0
DNAJB11-201 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie 41 141 19 19 2
DR1-202 DR1 Q01658 Protein Dr1 chr1 Not Cancer Driver No 1 hippie, biogrid 18 85 11 11 0
E2F1-201 E2F1 Q01094 Transcription factor E2F1 chr20 Not Cancer Driver No 1 hippie 39 273 17 17 0
EDC4-201 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 109 702 56 56 0
EFHC2-202 EFHC2 Q5JST6 EF-hand domain-containing family member C2 chrX Not Cancer Driver No 1 intact, hippie 65 50 7 7 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 346 223 30 30 1
ELF1-201 ELF1 P32519 ETS-related transcription factor Elf-1 chr13 Not Cancer Driver No 1 hippie 59 473 48 48 0
ELF4-201 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX Census, Compendium Yes 1 intact, hippie 63 487 46 46 2
EPS8-201 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 Not Cancer Driver No 1 intact, hippie 82 461 35 35 0
FAM124A-202 FAM124A Q86V42 Protein FAM124A chr13 Not Cancer Driver No 1 intact, hippie 60 359 33 33 0
FHL2-211 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
GADD45A-202 GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 Not Cancer Driver No 1 hippie, biogrid 8 40 4 4 0
GATA1-202 GATA1 P15976 Erythroid transcription factor chrX Census, Compendium Yes 1 intact, hippie 57 242 34 34 5
GOLGA2-201 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 intact, hippie 84 859 71 71 0
HCFC1-201 HCFC1 P51610 Host cell factor 1 chrX Not Cancer Driver No 1 hippie, biogrid 201 1349 135 135 0
HCFC2-201 HCFC2 Q9Y5Z7 Host cell factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 68 279 28 28 0
HECW2-212 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 272 848 157 157 4
HNF4A-201 HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 113 127 44 44 5
HOXA1-202 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 62 261 44 44 0
HSD17B14-201 HSD17B14 Q9BPX1 17-beta-hydroxysteroid dehydrogenase 14 chr19 Not Cancer Driver No 1 hippie, biogrid 26 42 7 7 0
HSPB2-201 HSPB2 Q16082 Heat shock protein beta-2 chr11 Not Cancer Driver No 1 hippie, biogrid 16 103 7 7 0
HSPB2-C11orf52-201 HSPB2 Q16082 Heat shock protein beta-2 chr11 Not Cancer Driver No 1 hippie, biogrid 16 103 7 7 0
IKBKG-206 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 5 301 4 4 21
IKZF5-201 IKZF5 Q9H5V7 Zinc finger protein Pegasus chr10 Not Cancer Driver No 2 hippie, biogrid 30 283 25 25 0
KANSL1-202 KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 chr17 Not Cancer Driver No 1 hippie, biogrid 127 883 96 96 0
KANSL2-201 KANSL2 Q9H9L4 KAT8 regulatory NSL complex subunit 2 chr12 Not Cancer Driver No 1 hippie, biogrid 38 306 19 19 0
KANSL3-220 KANSL3 Q9P2N6 KAT8 regulatory NSL complex subunit 3 chr2 Not Cancer Driver No 1 hippie, biogrid 70 549 42 42 0
KAT14-202 KAT14 Q9H8E8 Cysteine-rich protein 2-binding protein chr20 Not Cancer Driver No 2 intact, hippie 87 344 39 39 0
KAT2A-201 KAT2A Q92830 Histone acetyltransferase KAT2A chr17 Not Cancer Driver No 3 hippie, biogrid 70 251 11 11 0
KAT2B-201 KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 1 hippie, biogrid 78 268 20 20 0
KAT8-201 KAT8 Q9H7Z6 Histone acetyltransferase KAT8 chr16 Not Cancer Driver No 1 hippie, biogrid 57 156 18 18 4
KDM6A-201 KDM6A O15550 Lysine-specific demethylase 6A chrX Census, Compendium Yes 1 hippie, biogrid 143 648 58 58 0
KLF12-203 KLF12 Q9Y4X4 Krueppel-like factor 12 chr13 Not Cancer Driver No 1 hippie 46 338 38 38 0
KLF3-201 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 1 intact, hippie 43 243 31 31 0
KLF8-204 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 intact, hippie 44 271 32 32 0
KMT2A-201 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 1 hippie, biogrid 342 3148 263 263 0
KMT2B-201 KMT2B Q9UMN6 Histone-lysine N-methyltransferase 2B chr19 Compendium Yes 1 hippie, biogrid 248 1900 136 136 3
KYAT1-201 KYAT1 Q16773 Kynurenine--oxoglutarate transaminase 1 chr9 Not Cancer Driver No 1 intact, hippie 40 5 1 1 0
LMO2-202 LMO2 P25791 Rhombotin-2 chr11 Census Yes 2 intact, hippie, biogrid 24 14 0 0 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 402 91 13 13 20
LZTR1-221 LZTR1 Q8N653 Leucine-zipper-like transcriptional regulator 1 chr22 Census, Compendium Yes 1 intact, hippie 125 106 18 18 26
MAD2L1-201 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie, biogrid 21 12 1 1 0
MAGEA10-202 MAGEA10 P43363 Melanoma-associated antigen 10 chrX Not Cancer Driver No 2 intact, hippie, biogrid 94 170 45 45 0
MAML3-202 MAML3 Q96JK9 Mastermind-like protein 3 chr4 Not Cancer Driver No 1 intact, hippie 85 1128 85 85 0
MBIP-203 MBIP Q9NS73 MAP3K12-binding inhibitory protein 1 chr14 Not Cancer Driver No 4 hippie, biogrid 30 192 13 13 0
MCRS1-201 MCRS1 Q96EZ8 Microspherule protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 47 152 13 13 0
MYC-206 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 72 325 41 41 0
MYOD1-201 MYOD1 P15172 Myoblast determination protein 1 chr11 Census Yes 1 hippie 35 246 26 26 0
NCAPH2-205 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 Not Cancer Driver No 2 hippie, biogrid 48 338 26 26 0
NFIX-214 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 intact, hippie 45 305 26 26 6
PBXIP1-202 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 intact, hippie 69 606 60 60 0
PCBD1-201 PCBD1 P61457 Pterin-4-alpha-carbinolamine dehydratase chr10 Not Cancer Driver No 1 hippie, biogrid 5 7 0 0 3
PCBD2-201 PCBD2 Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 chr5 Not Cancer Driver No 1 hippie 5 3 0 0 0
PFDN4-201 PFDN4 Q9NQP4 Prefoldin subunit 4 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 13 41 3 3 0
PHF20-203 PHF20 Q9BVI0 PHD finger protein 20 chr20 Not Cancer Driver No 1 hippie, biogrid 100 667 61 61 0
PHF20L1-209 PHF20L1 A8MW92 PHD finger protein 20-like protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 109 646 66 66 0
PIAS4-201 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie, biogrid 40 143 18 18 0
PICK1-201 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 intact, hippie 36 49 1 1 0
POLE4-205 POLE4 Q9NR33 DNA polymerase epsilon subunit 4 chr2 Not Cancer Driver No 1 hippie, biogrid 3 45 0 0 0
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 60 44 3 3 3
PPP1R13B-201 PPP1R13B Q96KQ4 Apoptosis-stimulating of p53 protein 1 chr14 Not Cancer Driver No 1 intact, hippie 87 821 70 70 0
PRPS2-202 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie, biogrid 42 4 1 1 0
PSMC3-201 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 3 intact, hippie, biogrid 38 131 8 8 0
PSME3-210 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 16 25 5 5 0
RBBP5-201 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 36 218 12 12 0
RERE-204 RERE Q9P2R6 Arginine-glutamic acid dipeptide repeats protein chr1 Not Cancer Driver No 1 hippie, biogrid 154 1307 131 131 0
RFPL4B-201 RFPL4B Q6ZWI9 Ret finger protein-like 4B chr6 Not Cancer Driver No 3 hippie, biogrid 53 0 0 0 0
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 126 220 23 23 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie, biogrid 9 120 5 5 0
RPL37A-210 RPL37A P61513 Large ribosomal subunit protein eL43 chr2 Not Cancer Driver No 1 hippie, biogrid 4 0 0 0 0
SETD1A-201 SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 Not Cancer Driver No 1 hippie, biogrid 111 1329 99 99 5
SETD1B-202 SETD1B Q9UPS6 Histone-lysine N-methyltransferase SETD1B chr12 Census, Compendium Yes 1 hippie, biogrid 22 1482 18 18 4
SGF29-201 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 5 intact, hippie 25 132 12 12 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 8 70 6 6 0
SUPT20H-201 SUPT20H Q8NEM7 Transcription factor SPT20 homolog chr13 Not Cancer Driver No 1 hippie, biogrid 75 423 43 43 0
SUPT3H-202 SUPT3H O75486 Transcription initiation protein SPT3 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 37 49 2 2 0
SUPT7L-201 SUPT7L O94864 STAGA complex 65 subunit gamma chr2 Not Cancer Driver No 1 hippie, biogrid 31 281 22 22 0
TADA1-201 TADA1 Q96BN2 Transcriptional adapter 1 chr1 Not Cancer Driver No 1 hippie, biogrid 28 116 10 10 0
TADA2A-205 TADA2A O75478 Transcriptional adapter 2-alpha chr17 Not Cancer Driver No 3 intact, hippie, biogrid 39 70 4 4 0
TADA2B-201 TADA2B Q86TJ2 Transcriptional adapter 2-beta chr4 Not Cancer Driver No 1 hippie, biogrid 40 128 13 13 0
TADA3-201 TADA3 O75528 Transcriptional adapter 3 chr3 Not Cancer Driver No 4 hippie, biogrid 42 353 32 32 0
TAF5L-201 TAF5L O75529 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L chr1 Not Cancer Driver No 1 hippie, biogrid 68 70 10 10 0
TAF6L-201 TAF6L Q9Y6J9 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L chr11 Not Cancer Driver No 1 hippie, biogrid 59 246 20 20 0
TAF9-201 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 Not Cancer Driver No 1 hippie, biogrid 19 203 14 14 0
TAF9B-201 TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX Not Cancer Driver No 1 hippie, biogrid 30 189 22 22 0
TERF2IP-201 TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 20 312 12 12 0
TFAP4-201 TFAP4 Q01664 Transcription factor AP-4 chr16 Compendium Yes 1 hippie 49 287 41 41 0
THRSP-201 THRSP Q92748 Thyroid hormone-inducible hepatic protein chr11 Not Cancer Driver No 1 hippie, biogrid 20 47 5 5 0
TP53BP1-201 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 159 1638 131 131 0
TRAF2-201 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 intact, hippie 51 4 1 1 0
TRIM22-201 TRIM22 Q8IYM9 E3 ubiquitin-protein ligase TRIM22 chr11 Not Cancer Driver No 1 hippie 64 27 0 0 0
TRRAP-202 TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 hippie, biogrid 431 402 47 47 8
WDR37-201 WDR37 Q9Y2I8 WD repeat-containing protein 37 chr10 Not Cancer Driver No 1 hippie, biogrid 45 155 11 11 8
WDR5-201 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 4 hippie, biogrid 18 37 1 1 0
YEATS2-201 YEATS2 Q9ULM3 YEATS domain-containing protein 2 chr3 Not Cancer Driver No 2 hippie, biogrid 126 986 91 91 0
YY1-201 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 1 hippie 29 337 21 21 2
ZBTB9-201 ZBTB9 Q96C00 Zinc finger and BTB domain-containing protein 9 chr6 Not Cancer Driver No 1 intact, hippie 52 256 34 34 0
ZNF212-201 ZNF212 Q9UDV6 Zinc finger protein 212 chr7 Not Cancer Driver No 1 intact, hippie 45 289 19 19 0
ZNF496-206 ZNF496 Q96IT1 Zinc finger protein 496 chr1 Not Cancer Driver No 1 hippie 90 391 56 56 0
ZNF513-201 ZNF513 Q8N8E2 Zinc finger protein 513 chr2 Not Cancer Driver No 1 intact, hippie 62 294 40 40 1
ZNF608-209 ZNF608 Q9ULD9 Zinc finger protein 608 chr5 Not Cancer Driver No 1 hippie, biogrid 117 1435 114 114 0
ZNF653-201 ZNF653 Q96CK0 Zinc finger protein 653 chr19 Not Cancer Driver No 1 hippie, biogrid 62 375 41 41 0